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Biomedical subjects

F Terrier

Publications and source records attributed to F Terrier.

At least 127 records · Page 7Linked to original sources
PubMed1983

[Computer tomography in acute pyelonephritis].

Computer tomography of the kidneys was performed on 30 patients with acute renal infections (acute suppurative pyelonephritis, acute renal abscess, infected cyst, pyelonephrosis, calculus perforation, retroperitoneal abscess). Computer tomography provided more accurate information concerning the extent of the renal and extra-renal inflammatory process than did the urogram or sonogram. This may significantly affect the choice of treatment, particularly concerning the use of drugs or of surgery. Angiography and retrograde pyelography may be used in selected cases, especially where there is a suspicion of acute bacterial nephritis, renal vein thrombosis or ureteric obstruction.

Acute Disease↗
PubMed1983

Morphologic aspects of hepatic abscesses at computed tomography and ultrasound.

The morphologic criteria of hepatic abscesses as demonstrated at computed tomography (CT) and ultrasound (US) were investigated in 27 patients and the diagnostic efficiency of both methods evaluated. Different appearances of hepatic abscess at CT and US were observed and investigated. No specific morphologic signs could be defined, since malignant neoplasms may show similar findings. Therefore, fine needle aspiration of possible hepatic abscesses should be performed to provide specific and bacteriologic diagnosis. US is an accurate method to evaluate patients with possible hepatic abscess. However, CT should be preferred in critically ill patients and postoperatively, since the diagnostic accuracy of CT is not limited by bowel gas, sutures and drainage tubes.

Adolescent↗
PubMed1983

[Computer tomography-guided puncture of the retroperitoneal space].

A CT-guided fine-needle puncture was performed in 42 patients with renal or retroperitoneal space-occupying growths identified by means of computed tomography. In 18 out of 24 patients (75%), CT-guided fine-needle puncture enabled verification of malignant neoplasias, relapses and metastases by means of identification of malignant cells. In 9 out of 13 patients suspected of retroperitoneal abscess, fine-needle puncture helped to establish the diagnosis by a positive bacteriological finding. In 5 cases, CT-guided anterograde pyelography and percutaneous nephrostomy were effected after puncture of the renal pelvis by means of sonography had failed. CT-guided puncture should be used as an additional or complementary examination over and above computed tomography alone whenever a space-occupying growth is present the aetiology of which remains unclear. CT-guided puncture is indicated on principle in retroperitoneal space-occupying growths which cannot be properly defined by sonography.

Abscess↗
PubMed1982

Computed tomography of intraperitoneal abscesses.

Eighty-seven patients with the clinical suspicion of an intraperitoneal abscess were examined by computed tomography. In 83 of these patients CT gave true positive or true negative results in reference to the diagnosis of local intraperitoneal fluids. The final diagnosis confirmed 28 abscesses in 26 patients. Most of these abscesses were in the left subphrenic space, the right subphrenic space, the right anterior subhepatic space, and the pelvis. The morphological criteria for intraperitoneal abscesses, shown by CT, are defined. Direct signs include form, impression on nonintestinal organs, density value, gas collection, pyogenic membrane, and infiltration in surrounding tissue. Indirect signs include ascites and pleural effusion and/or pulmonary infiltration. Differential diagnostic problems of intraperitoneal abscesses are discussed.

Abscess↗
PubMedDate not supplied

Niemann-Pick disease type C: nodular splenomegaly.

Niemann-Pick type C disease (NPCD) is an autosomal recessive storage lipidosis due to a disorder of cholesterol esterification leading to the accumulation of sphingomyelin and cholesterol in the brain, liver, and spleen. The disease is usually diagnosed when neurological symptoms appear. We report an unusual presentation of NPCD in a young asymptomatic adult with isolated nodular splenomegaly.

Adult↗
PubMedDate not supplied

MRI findings in Caroli's disease and intrahepatic pigmented calculi.

This paper reports a case of Caroli's disease confined to the left lobe of the liver that mimicked left portal vein thrombosis on MRI studies because of the very high signal intensity on T1-weighted images of intrahepatic pigmented calculi. The preoperative diagnosis was a cholangiocarcinoma infiltrating the left hepatic bile duct and portal branch. The final macroscopic and histological diagnosis was Caroli's disease of the left liver lobe with wide enlarged left bile duct containing multiple pigmented calculi.

Aged↗
PubMedDate not supplied

Specificity of SPIO particles for characterization of liver hemangiomas using MRI.

We investigated the specificity of superparamagnetic iron oxide (SPIO)-enhanced T1-weighted spin-echo (SE) magnetic resonance (MR) images for the characterization of liver hemangiomas. When imaging liver hemangiomas, which are the most frequent benign liver tumors, a method with very high specificity is required, which will obviate other studies, follow-up, or invasive diagnostic procedures such as percutaneous biopsy. Eighty-three lesions were examined by MR imaging at 1.5 T before and after intravenous injection of SPIO particles. Lesions were categorized as follows according to the final diagnosis: 37 hemangiomas, nine focal nodular hyperplasias (FNHs), 19 hepatocellular carcinomas (HCCs), and 18 metastases. Their signal intensity values were normalized to muscle and compared. The only lesions showing a significant increase in signal intensity ratio (lesion to muscle) on postcontrast T1-weighted SE images were hemangiomas (p < 0.001). The signal intensity ratio of hemangiomas increased on average by 70%. Based on receiver operating characteristic analysis and using a cutoff level of 50% signal increase, the specificity and sensitivity of SPIO-enhanced MR imaging for the characterization of hemangiomas would be 100% and 70%, respectively. The T1 effect of SPIO particles can help differentiate hemangiomas from other focal liver lesions such as FNHs, HCCs, and metastases and may obviate biopsy. When using SPIO particles for liver imaging, it is useful to add a T1-weighted sequence to T2-weighted images, thereby providing additional information for lesion characterization.

Adult↗
PubMedDate not supplied

Treatment of gastrointestinal hemorrhage.

BACKGROUND: We assessed the value of selective arteriography in the diagnosis and management of acute gastrointestinal hemorrhage. METHODS: We reviewed the records of 107 consecutive patients who had gastrointestinal hemorrhage and underwent selective arteriography between January 1992 and October 2003: 10 had upper gastrointestinal bleeding, 79 had lower gastrointestinal bleeding, and 18 had varicose bleeding with portal hypertension. Selective embolization was attempted in 15 patients to obtain hemostasis. Angiographic findings were reviewed and prospective reports were compared with the final diagnosis and outcome. RESULTS: Of 129 angiographic studies, 36 correctly revealed the bleeding site and 93 were negative. Extravasation was seen in 24 cases at the level of stomach (n = 2), duodenum (n = 1), small bowel (n = 5), or colon (n = 16). Indirect signs of bleeding sources were identified in 12 patients (stomach in one, small bowel in four, large bowel in four, liver in three). Transcatheter embolization induced definitive hemostasis in 11 of 15 patients (73%), namely in the stomach (n = 2), small bowel (n = 3), colon (n = 7), and liver (n = 3). Three patients required surgery after embolization. CONCLUSION: Abdominal arteriography may localize gastrointestinal bleeding sources in approximately one-third of cases. Selective embolization may provide definitive hemostasis in most instances.

Adolescent↗
PubMedDate not supplied

Ablation of hepatocellular carcinoma by percutaneous ethanol injection: imaging findings.

Since PEI is a treatment based on imaging techniques, the radiologist should be familiar with the various findings that may be observed after PEI on US, CT, and MR images immediately after treatment and during later follow-up. Although US is well suited for performing PEI, contrast-enhanced CT currently is the most commonly used imaging method to evaluate the effect of PEI. Residual, nodular areas of contrast enhancement correlate well with residual tumor and warrant additional treatment. Although the findings on MR images obtained after PEI are more complex, MR imaging may be used as an alternative to CT.

Antineoplastic Agents↗
PubMedDate not supplied

[Occult breast cancer. Detection and radioguided surgery with 99mTc-MIBI].

We include those patients who present with an isolated metastasis of axillary adenopathy in the occult primary breast cancer group. Presumably, the primary tumor is a primitive breast carcinoma, unsuspected until this moment and not clinically demonstrable by mammography or ultrasonography. When no method succeeds in confirming the primary breast lesion, the patients are usually treated assuming the existing of breast cancer. Several diagnostic methods have been used to find the primary breast lesion. Magnetic Resonance imaging (MRI), Positron Emission (PET) and Doppler sonography have been used in this way and several papers present the results reached with them. Our group incorporates detection and radioguided surgery with 99mTechnetium (99mTc) methoxyisobutil isonitrile into the study of these patients. We perform a planar scintimammography and SPECT (Single Photon Emission Computed Tomography) with 99mTc-MIBI. If the radioisotopic method shows a functional image compatible with a carcinoma, a gamma detecting probe is then used to locate the lesion and guide its surgical removal. In this paper, we present the application of the technique in 5 cases and describe the technique and its possibilities. Its advantages are explained in comparison with other methods. The dosimetric values found in the performance of the technique are reported. We consider that detection and radioguided surgery with 99mTc-MIBI in the diagnosis and treatment of occult breast cancer adds an effective tool and means progress in the approach to this disease.

Adenocarcinoma↗
PubMedDate not supplied

[MRI evaluation of carpal tunnel morphology after carpal tunnel release by a retinaculum lengthening technique].

AIM: The benefits of maintaining the pulley function of the flexor retinaculum in carpal tunnel release by lengthening or reconstructing it have been described. Quantitative MR imaging was used to investigate the morphological changes after open carpal tunnel release by such a retinaculum lengthening technique. METHOD: Ten patients had bilateral carpal tunnel MRI pre- and postoperatively. The MRI examinations were performed with a 1.5 Tesla imaging system and wrist coils. Carpal tunnel volume, carpal arch width, median nerve position and flexor tendon position in relation to the hamate-trapezial axis were recorded . RESULTS: Like other methods of carpal tunnel release with complete division of the flexor retinaculum, the retinaculum lengthening technique showed a significant postoperative increase of carpal tunnel volume. Carpal arch width increased only slightly. There was a significant palmar displacement of the median nerve but not of the flexor tendons. CONCLUSION: The findings support the hypothesis that maintenance of the pulley function of the retinaculum may lead to an early postoperative recovery of grip strength. In spite of some difficulties in application quantitative MR imaging may be a useful tool in evaluating the carpal tunnel morphology.

Adult↗
PubMedDate not supplied

MR imaging of body fluid collections.

To evaluate the potential of magnetic resonance (MR) to characterize body fluids in vivo, we determined the relaxation times and the relative MR signal intensities of 42 body fluid collections in 42 patients. Twelve normal volunteers served as controls. We also studied albumin solutions at different concentrations and blood at various periods in vitro. Because of their long T1 relaxation times, most nonhemorrhagic fluid collections had low to intermediate intensity on images obtained with short repetition time (TR) and short echo time (TE) settings. Although the relaxation times and relative MR signal intensities of noninfected collections differed from those of infected collections, the values overlapped. On images obtained with short TR and short TE, blood in acute hemorrhages had intermediate signal intensity and serum in subacute hemorrhagic collections was the only pathologic fluid producing high signal intensity. Because of their relatively long T2 values, all the fluid collections were intense on images obtained with long TR and long TE settings; consequently, differences in intensity were less evident than on images obtained with short TR and short TE settings. Magnetic resonance allows reliable discrimination of subacute hemorrhagic collections from collections of other types, but the differentiation between acute hemorrhagic collections; nonhemorrhagic, noninfected collections; and nonhemorrhagic, infected collections is less accurate.

Adolescent↗
PubMedDate not supplied

Two- and three-dimensional phase contrast MR angiography of the abdomen.

Protocols for two- and three-dimensional phase contrast magnetic resonance angiography of the major vessels in the abdomen were developed and demonstrated in healthy volunteers. Phase contrast imaging provides excellent suppression of stationary tissue signal and can be used to quantify the speed and direction of flow in a given vessel. The two-dimensional protocols provide rapid breath-held images, which proved useful for anatomical localization. The three-dimensional studies required longer acquisition times but provided superior image quality. Artifacts from bowel and respiratory motion were not significant with either protocol. Vasculature detected includes the renal, splenic, hepatic, and mesenteric systems as well as the aorta and inferior vena cava.

Abdomen↗
PubMedDate not supplied

Enhancement of liver hemangiomas on T1-weighted MR SE images by superparamagnetic iron oxide particles.

OBJECTIVE: Superparamagnetic iron oxide (SPIO) particles are phagocytosed by cells of the macrophage-monocytic phagocytic system. They are usually used in MRI as a negative contrast agent, because of their strong T2* effect, to improve detection of tumors in the liver and spleen. However, they also have a potent T1 relaxivity. In the current study, we describe this T1 effect in liver hemangiomas. MATERIALS AND METHODS: Twelve patients (nine women and three men, aged from 38 to 76 years) with liver hemangiomas were examined by means of MRI at 1.5 T before and after intravenous administration of SPIO particles at a dose of 15 mumol Fe/kg body wt. Signal intensity was measured from regions of interest. RESULTS: Whereas on postcontrast T2-weighted SE images the hemangiomas showed on average a signal drop of 20% (p = 0.011) and 49% (p = 0.001) (first and second echo, respectively), their signal increased by 106% (p = 0.001) on postcontrast T1-weighted SE images. CONCLUSION: The T1 effect (signal enhancement) we observed in liver hemangiomas after infusion of SPIO particles could prove to be a useful new diagnostic feature that would help characterize these common lesions and differentiate them from other liver tumors.

Adult↗
PubMedDate not supplied

Long-term changes induced by high-dose irradiation of the head and neck region: imaging findings.

High-dose irradiation is an effective treatment for tumors in the head and neck. Radiation-induced complications are uncommon but may result in chronic, progressive symptoms months or years after therapy. In 19 (1%) of 1,950 patients who underwent successful high-dose irradiation of head and neck tumors over a 5-year period, delayed radiation-induced changes were documented with imaging. These changes can be categorized as soft-tissue, bone, and cartilage necrosis; fibrosis leading to functional disorders; arteriopathy; central nervous system reactions, delayed myelopathy, and cranial nerve palsies; and the development of meningiomas. Radiologic features of radiation-induced soft-tissue, bone, and cartilage necrosis include inflammatory swelling adjacent to the area of involvement; deep gas-containing ulcerations; sclerotic appearance of the involved cartilages; fragmentation and sloughing of necrotic bone or cartilage; and abscess and fistula formation. Masticator muscle fibrosis appears as an area of diffusely increased signal intensity on T2-weighted images and of enhancement on postcontrast T1-weighted images. Radiation arteriopathy may manifest as occlusion, subocclusive sclerotic or atheromatous plaque, localized mural thrombus, aneurysm, or, rarely, spontaneous rupture. In central nervous system reactions, imaging findings include demyelination foci in the white matter, focal radiation necrosis, and severe brain atrophy. Radiation-induced meningiomas display the same imaging features as non-radiation-induced meningiomas at computed tomography, magnetic resonance imaging, and angiography, although follow-up examinations may reveal their more aggressive biologic behavior. Knowledge of the radiologic appearance of radiation-induced changes may prevent misinterpretations and facilitate treatment.

Aged↗
PubMedDate not supplied

Non-squamous cell neoplasms of the larynx: radiologic-pathologic correlation.

A variety of benign and malignant non-squamous cell neoplasms may affect the larynx. Most of these uncommon laryngeal neoplasms are located beneath an intact mucosa, making diagnosis difficult with endoscopy alone, and sampling errors may occur if only traditional superficial biopsies are performed. In some laryngeal neoplasms, radiologic evaluation allows the correct diagnosis. Hemangiomas have very high signal intensity at T2-weighted magnetic resonance (MR) imaging and strong enhancement at both computed tomography (CT) and MR imaging after administration of contrast material. Phleboliths, which are pathognomonic for hemangiomas, are easily identified at CT. Chondrogenic tumors typically manifest with coarse or stippled calcifications at CT. Because of their high water content, chondrogenic tumors have very high signal intensity on T2-weighted MR images, whereas only moderate enhancement is observed after administration of contrast material. Lipomas typically manifest at both CT and MR imaging as homogeneous nonenhancing lesions. They are isoattenuating to subcutaneous fat at CT and isointense relative to subcutaneous fat with all MR pulse sequences. Metastases from renal adenocarcinoma typically demonstrate strong contrast enhancement and flow voids at MR imaging, and metastases from melanotic melanoma usually have high signal intensity on T1-weighted MR images and low signal intensity on T2-weighted images owing to the paramagnetic properties of melanin. Although radiologic findings are nonspecific in most other non-squamous cell neoplasms of the larynx (eg, Kaposi sarcoma, hematopoietic tumors, tumors of the minor salivary glands, metastases from amelanotic melanoma), cross-sectional imaging can play an important role in the diagnostic work-up of these unusual tumors by delineating the extent of submucosal tumor spread and directing the endoscopist to the appropriate site for the deep, transmucosal biopsies needed to establish the diagnosis. In addition, CT and MR imaging are crucial for posttherapeutic monitoring and early detection of local recurrence.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Treatment of hepatocellular carcinoma at the dawn of the third millennium: liver transplantation and its alternatives.

Hepatocellular carcinoma is one of the most frequent tumors worldwide, and its frequency is increasing. The management of hepatocellular carcinoma has changed in recent years, this because screening allows to discover tumors at an earlier stage, and because of effective treatments are available, such as liver transplantation, liver resection, percutaneous ablation and transarterial chemoembolization. Each one of these treatments has its own advantages and drawbacks, and range of application according to the stage of the tumor and of the underlying liver disease. This review summarizes the recent progress in the management of HCC and the practice in our unit.

Carcinoma, Hepatocellular↗