Search PubMed⌕ Search

Biomedical subjects

F T Zugibe

Publications and source records attributed to F T Zugibe.

36 records · Page 2Linked to original sources

Metropolitan forensic anthropology team (MFAT) case studies in identification: 3. Identification of John J. Sullivan, the missing journalist.

Skeletal remains removed from an unmarked grave in El Salvador were intensively studied by a team of forensic science experts. Even though the skull, teeth, and several major bones were missing, a positive identification was made of the missing journalist. This was contrary to reports submitted to the State Department by Salvadorian officials. All of the methods used in this investigation, which includes a new method for simultaneously assessing sex and race by discriminant function analysis that was tested by application, are fully described. The international background of this case and information regarding the cause of death is discussed.

Adult↗

Identification of a murder weapon by a peculiar blunt force injury pattern and histochemical analysis.

Attempts to determine the instrument in the brutal killing of a middle-aged male resulted in the positive identification of an auto jack column as the actual instrument used. This was accomplished by the use of three modalities: (1) the edge of the jack column conformed exactly to a multi-curved laceration in the forehead (site of lethal injury), (2) blood found within this edge of the jack column afforded the same blood type as that of the victim, and (3) tissue sections made of the blood and debris from this edge of the jack column revealed tissue fragments containing human keratin (antihuman keratin technique) and positive staining with collagen stains.

Adult↗

Usefulness of Doppler echocardiography in cardiac pacing: assessment of mitral regurgitation, peak aortic flow velocity and atrial capture.

Doppler echocardiographic studies were performed in 14 patients with dual chamber pacemakers. Transmitral flow studies (12 patients) revealed absence of mitral regurgitation (MR) or no change in MR severity in 6, new development or increased MR during VVI and/or short or long AV interval lengths compared to more normal AV intervals (150-160 ms) in 5, and appearance of MR when the pacing mode was changed from VVI to DVI with a fixed AV interval of 250 ms in 1 patient. Aortic peak flow velocity measurements (7 patients) showed significant increases in stroke volume (range 9 to 25%, mean 19.5%) in all patients with DVI/VDD pacing compared to VVI pacing (4 patients) or to shortest available AV interval (3 patients). Presence of Doppler left atrial systolic flow correlated with evidence of atrial depolarization in all 7 patients in whom high quality 12-lead surface electrocardiograms were obtained. Our preliminary study demonstrates the value of Doppler echocardiography in the "fine tuning" of cardiac pacemaker parameters by assessment of presence, absence, or change in severity of MR, estimation of relative changes in stroke volume, and determination of atrial capture in different pacing modes and at various AV intervals.

Arrhythmias, Cardiac↗

Sudden death related to the use of psychotropic drugs.

Analysis of data regarding deaths related to psychotropic drugs suggests that many unrecognized or unreported deaths have occurred in psychiatric hospitals. Since the adverse effects of psychotherapeutic drugs can occur in the therapeutic range, critical recommendations for monitoring must be initiated, more trained personnel implemented, and current personnel given additional training as indicated.

Airway Obstruction↗

Arthrodentoosteodysplasia: a genetic "acroosteolysis" syndrome.

From one personal patient and 13 reported in the literature, arthrodentoosteodysplasia (ADOD) is defined as a heritable disorder of connective tissue with the main clinical manifestations of laxity of joints, early loss of teeth, and multiple osteolytic lesions, including acroosteolysis on roentgenographic examination. These lesions probably represent "pseudoosteolysis" with faulty primary bone formation rather than true osteolysis of previously normal bone. ADOD is an example of relational pleiotropism with most clinical manifestations representing secondary effects and deformities. The cranial sutures frequently remain uncalcified and contain multiple wormian bones in unusual places. Secondary deformities may be progressive and affect primarily the skull, spine, fingers and fingernails. Pathologic fractures are clinically the most important manifestation of ADOD. In one family the mother and four of her six children were affected. The other nine case reports describe sporadic instances. ADOD is presumed to be caused by an autosomal dominant gene, the sporadic cases representing new mutations.

Abnormalities, Multiple↗

Gunshot wound to the back of the head--self defence vs homicide.

A police officer attended the scene of a burglary in progress and, following a pursuit through the house with his gun in hand, short the burglar in the back of the head. the officer pleased self-defense alleging that the burglar had whirled around holding what was perceived as a gun in this left hand and that he had reflexively pulled the trigger of his own gun. When he examined the body, a black yarmulke was present near the outstretched hand of the burglar. The results of a reconstruction were consistent with the details of the police officer's deposition.

Craniocerebral Trauma↗