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Biomedical subjects

F T Nichols

Publications and source records attributed to F T Nichols.

40 records · Page 3Linked to original sources

The droopy shoulder syndrome.

We found that patients with thoracic outlet syndrome have: (1) low-set, "droopy" shoulders and long swan neck; (2) pain in the neck, shoulder, chest, arms, or hands; (3) aggravation of symptoms by downward traction and relief by propping up the arms; (4) occurrence in women; (5) absence of abnormal vascular, neurologic, and electrical findings; (6) a Tinel's sign over the brachial plexus; and (7) T-2 vertebra visible above the shoulders on lateral cervical spine films. In our experience, droopy shoulder syndrome has accounted for most cases of thoracic outlet syndrome but is largely unrecognized by physicians. Recognition of this syndrome should lead to a better understanding of the underlying pathophysiology and prevent unnecessary surgery.

Adult↗

Irreversible neurologic complications of metrizamide myelography.

Metrizamide, a major contrast agent for myelographic procedures, has rarely been reported to cause irreversible neurologic complications. The major transient neurologic alterations include neuropsychological reactions, generalized tonic-clonic seizures, and headaches. Two cases of irreversible spinal neurologic deficits resulting from metrizamide myelography are reported, and the factors that may increase the risks of complications in metrizamide myelographic studies are discussed, including preexisting dehydration, patient positioning, and the concentration of contrast agent.

Adult↗

Mitral valve prolapse and stroke: echocardiographic evidence for a missing causative link.

There is general acceptance of a causal connection between mitral valve prolapse and systemic embolic events. The precise mechanism, however, remains controversial, with current hypotheses favoring the embolization of thrombotic deposits from the abnormal mitral valve. It might be surmised that echocardiography could easily document the presence of such thrombi, but actually, this has never been reported previously. Described herein is a patient with a severe cerebrovascular accident in whom echocardiography clearly demonstrated a mass of high embolic potential attached directly to the prolapsing mitral valve leaflet.

Adult↗

MR and CT investigation of cerebrovascular disease in sickle cell patients.

Stroke is a common complication of sickle cell disease. Using MR and CT, we studied 10 patients with sickle cell disease and a history of stroke and compared these findings with those of 10 sickle cell patients without stroke. The purpose was to determine if MR could visualize the large vessel vasculopathy previously seen on angiography and to estimate the incidence of asymptomatic abnormalities in the nonstroke group. MR consistently demonstrated the major intracranial arteries and showed three cases with occlusion and three with stenosis of either the internal carotid or middle cerebral arteries. Infarctions were better delineated on MR but were also seen on CT. Seven cases with and two without stroke had high-signal white matter lesions on MR. Further research using cranial MR to develop noninvasive means of identifying sickle cell patients at risk for stroke is warranted.

Adolescent↗