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Biomedical subjects

F T Fork

Publications and source records attributed to F T Fork.

At least 55 records · Page 3Linked to original sources

Intravenous computed tomographic cholangiography in acute cholecystitis. A comparison with conventional cholangiography.

Forty-nine patients with clinical signs of acute cholecystitis underwent conventional and computed tomographic cholangiography. Among 39 patients with signs of contrast medium in the biliary system at both examinations there was a diagnostic discrepancy in only one patient. Conventional radiography demonstrated cholecystopathy in this patient while contrast medium in the gallbladder and an acute pancreatitis were found at computed tomography. Ten patients with an indeterminate conventional cholangiography had a conclusive computed tomographic examination. Twenty of 30 patients with an abnormal computed tomographic cholangiography underwent cholecystectomy and all had diseased gallbladders. All 17 patients with histopathologically confirmed acute cholecystitis had signs of subserosal edema and/or changes in the omental fatty tissue adjacent to the gallbladder at computed tomography. A layer of tissue of water-density adjacent to the gallbladder and/or changes in omental fatty tissue were also seen in one patient with congestive heart failure and in one with a penetrating duodenal ulcer. None of the 19 patients with a normal computed tomographic cholangiography had a proven acute cholecystitis.

Acute Disease↗

Radiology in primary gastric lymphoma.

Upper gastro-intestinal radiographic studies in 19 patients with primary gastric lymphoma (PGL) were reviewed and compared with studies in matched patients with adenocarcinoma. The very large infiltrating tumour (n = 10) was significantly more often found in patients with PGL, whereas the ulcerative lesion was the predominating feature in patients with adenocarcinoma (n = 15). Furthermore a coarse, irregular mucosal pattern and shallow ulcerations were frequently associated with PGL (n = 18). There was no difference in survival time between the two groups of patients. PGL is a rare disease, with two new cases annually in a population of 230 000, and therefore easily misjudged.

Adenocarcinoma↗

Herniography in atypical inguinal hernia.

In patients with unclear groin pain herniography has revealed hernia in 36% of the patients with a normal physical examination. Most of the hernias detected on herniography are of indirect, direct or femoral type. The former two are found predominantly among men and the latter among women. These types of hernia are defined herniographically according to their location and shape. Whether or not a hernia is present is usually obvious although small hernias may be obscured by pelvic bone and contrast medium in the inguinal fossae and pouch of Douglas. In most patients the hernias are conspicuous and easy to classify correctly. Problems may, however, arise in the precise definition of some types of hernia. In this respect positive contrast herniography contributes to the pre-operative evaluation in patients with inguinal hernia. The aim of the present report is to describe some less well-known herniographic findings. The clinical impact of the particular findings is discussed.

Adolescent↗

Reliability of routine double-contrast examination (DCE) of the large bowel in polyp detection: a prospective clinical study.

A total of 2,118 consecutive patients, examined with double-contrast examination of the large bowel (DCE), were evaluated radiographically, clinically, and endoscopically for up to 48 months. A total of 402 polyps were diagnosed during the follow-up period. Of these, 307 were revealed at the first DCE and 95 at subsequent endoscopy or autopsy. The accuracy of the DCE for demonstrating or excluding patients with polypoid lesions of the colon was 97%, whereas the predictive value of a positive DCE report was 96% and a negative one, 97%. However, the ability to demonstrate every known polyp at DCE was only 63%, although the probability of a polypoid lesion demonstrated at DCE being a true polyp was 92%.

Adenoma↗

Recognition of gas in gallstones in routine computed tomograms of the abdomen.

In a consecutive group of 1,067 noncholecystectomized patients referred for computed tomography including the upper abdomen, gallstones were seen in 13%. In 4% of the patients with gallstones, gas-containing calculi were found. On reviewing the conventional plain films such stones were revealed in less than one-half of the patients.

Cholelithiasis↗

Reliability of routine double contrast examination of the large bowel: a prospective study of 2590 patients.

A total of 2590 consecutive patients referred for double contrast examination (DCE) of the large bowel were followed up radiographically, clinically, endoscopically, and histopathologically during a four year period. The patients were put into two groups on the basis of the presence or absence of radiographic evidence of colonic disease at the first--that is, index examination. By comparing the findings obtained at the index double contrast examination with those obtained during follow up, the sensitivity, specificity, and accuracy of the index double contrast examination were all calculated at 0.84. The predictive value of a positive report was 0.93 and that of a negative report 0.70. If, however, patients with normal double contrast examinations at the start of this series and not examined further during the follow up period were accepted as free from significant colonic disease, the predictive value of a negative report increased to 0.93. Double contrast examination is thus a reliable method for showing the presence of colonic lesions and therefore considerably helps the management of a given case.

Adolescent↗

Double contrast examination in carcinoma of the colon and rectum. A prospective clinical series.

During a 9-month period, 2 590 patients were referred for radiographic examination of the large bowel. All but 55 of these examinations were performed according to the double contrast examination method. The patients were followed prospectively from 40 to 48 months. Carcinoma of the colon or rectum was disclosed in 96 patients and other malignant lesions in 7 others. The carcinomas in 93 patients were diagnosed at the primary DCE. During the follow-up period, carcinoma of the colon was revealed in another 10 patients, the malignancy having been obfuscated by diverticulitis in 3 patients and considered polyps in 6 others. The accuracy of the double contrast method was calculated at 99.3 per cent.

Adenoma↗

Colon cleansing regimens. A clinical study in 1200 patients.

The purgative effect of bisacodyl, anthraquinone glycosides (Cascara), and sodium picosulfate, alone or in combination with a saline purge and a tap water enema, was studied in 1200 patients. The cleansing effect was scored with regard to retained fecal residue evident on double-contrast studies of the colon. The combination of a contact laxative and a saline purge produced good cleansing effect in 52%-80% of the patients. With an additional tap water enema given 1 hour before the colon examination, however, 96% of the colons were clean. The taste and the effects of the cleansing systems were tolerated favorably by more than 90% of the patients. However, 17% reported restriction in work capacity on the day of bowel cleansing.

Adult↗

The double contrast examination in inflammatory large bowel disease. A prospective clinical, radiographic, and pathologic study.

In a prospective clinical series of 2371 consecutive patients referred for double contrast examination (DCE) of the large bowel, 154 had clinical and/or radiographic signs of inflammatory disease. The patients were followed up from May 1976 until May 1981. At the time of interpretation of the roentgenograms, the radiologist was unaware of clinical and laboratory findings. In 31 patients, organ specimens were studied histologically and in 101 other multiple endoscopic biopsies were available. Basing on the clinical observations and the pathology reports, the accuracy of the DCE was calculated at 99%; the predictive value of a positive DCE at 92, and that of a negative DCE at 99%.

Adolescent↗

Double contrast enema and colonoscopy in polyp detection.

The diagnostic accuracy of double contrast enema was assessed by colonoscopy of 250 consecutive patients with polypoid lesions that were observed at double contrast enema. The enema method detected 90% of all existing polypoid lesions, and gave false positive results in less than 3.5% Colonoscopy revealed 91% of the lesions. Double contrast enema is suitable as a screening procedure and, when used in combination with colonoscopy, only very few polyps will escape detection. The large number of neoplastic polyps detected in this retrospective series emphasises the necessity for a careful radiographic technique combined with colonoscopy to disclose and treat these potentially malignant lesions of the colon.

Adult↗

Ioglycamide acid (Bilivistan) low-dose drip-infusion cholangiography.

Fifty-five anicteric patients with acute upper abdominal pain were examined with low-dose drip-infusion cholangiography using ioglycamide acid (17 ml Bilivistan, 280 mg I/ml) given over two hours. Good visualization of the biliary system was achieved and no adverse effects were recorded. There was good agreement between the cholangiographic diagnostic and the peroperative findings. No false negative findings were disclosed.

Adult↗

Predictive value of small bowel radiography for recurrent Crohn Disease.

Small bowel radiographs of 53 patients who had remote surgery for Crohn disease were reviewed. In 10 of these, the radiographic studies could be compared with pathologic specimens from recent reoperations. The correlation of radiographic features and photographic and histopathologic alterations in these specimens was very close. Normal radiographs were found in 21 patients. In the other 32 patients, various types of inflammatory lesions were recorded. Submucosal edema was seen as broad folds in 23 patients, as irregular folds in 10 patients, and as absence of mucosal folds in nine patients. Superficial ulcerations were seen in 22 patients. Transmural lesions were seen in 14 patients but were seldom pronounced. Patients with normal postoperative small bowel radiographs had no signs of clinical recurrence, whereas 27% (4/15) of those with submucosal edema and superficial ulcerations had clinical signs of recurrence. In 87% (13/15) of patients with transmural lesions, there was clinical recurrence. Local progression could be documented in two of 20 patients. There were no instances of axial progression. Postoperative small bowel radiography seems to have useful predictive value for recurrent Crohn disease.

Adult↗

[The radiologic diagnosis of inguinal hernias. Experience with the use of intraperitoneal iodinated contrast media (author's transl)].

By injecting an iodine contrast medium into the abdominal cavity and by placing the patient in a position with the table somewhat elevated, it is easy to visualize the inguinal region. The examination is performed with the X-ray tube angulated caudally, and exposures are made while the patient is straining. The method is well adapted for patients with obscure pains in the groins, for patients operated for hernias but not cured of pain and for patients in whom symptoms recur postoperatively without clinical evidence of hernial relapse. The value of the methode appears from four short case reports.

Adult↗

Colon of the rat. An anatomic, histologic and radiographic investigation.

The anatomy and radiologic appearance of the colon in rats are described on the basis of 300 animals treated with carcinogenic agents and 40 normal rats. The macroscopic and microscopic appearance of the mucosa varies in the different parts of the colon. Lymphoid plaques are normal structures. The results justify a new anatomic nomenclature.

Animals↗

Roentgenology of the colon in Crohn's disease. Air contrast studies of the lesions and their development.

201 patients with Crohn's disease underwent air contrast examination of the colon. The Diagnosis was histologically confirmed in each case. Most of the pathological changes of Crohn's disease of the colon are manifested as alterations of the mucosal surface. These changes are excellently demonstrated by the air contrast technique. The roentgenologic findings in colonic Crohn's disease are being discussed as well as cecal deformities and rectal changes. Some conditions that may mimic colonic Crohn's disease are summarized. Finally the advantages and disadvantages with the air contrast technique are given.

Air↗

Dynamic aspects of colonic Crohn's disease.

Changing patterns of the lesions in colonic Crohn's disease were studied in 86 patients who underwent multiple consequetive roentgen examinations. Local progression of lesions was seen in 56 out of 86 patients; rapid local advancement from mild to severe lesions was not uncommon. Temporary regression of lesions was only seen in 7%; definitive permanent healing on conservative treatment was not observed. Preoperative extension of lesions was seen in 29%, with ultimate involvement of the rectum in 7% and development of anal fistulae in 17%. Clinical implications of the findings are briefly discussed.

Acute Disease↗