Biomedical subjects
F T Fitzgerald
Publications and source records attributed to F T Fitzgerald.
The case for internal medicine.
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Bedside teaching.
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Physical diagnosis versus modern technology. A review.
The role of physical diagnosis in an age of modern diagnostic technology has been evaluated by investigators assessing specific techniques in a number of areas, though there has been no systematic comprehensive study of the sensitivity, specificity, cost-benefit ratio, and reliability of physical diagnosis relative to technologic diagnostic tools. In a review of published studies comparing physical with nonphysical diagnostic techniques, the startling accuracy of physical diagnosticians in some areas contrasts sharply with the extremely poor correlation of physical findings with autopsy or imaging studies in others. In a time of constricting financial resources, physicians-and those who teach or judge physicians' skills-must begin to compare physical and nonphysical diagnostic techniques rigorously so that the best, safest, and least expensive diagnostic test is chosen in each clinical situation.
Alcoholism education.
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A survey on the prevalence of alcoholism among the faculty and house staff of an academic teaching hospital.
We studied the extent of alcoholism among faculty and house staff of an urban, university-based teaching hospital. Of 569 questionnaires sent, 282 (50%) were returned and 271 of these were complete enough to be interpretable. Of those responding, 12 (4%) were classified as alcoholic and 26 (10%) as possibly alcoholic. There was no statistically significant difference in the prevalence of alcoholism in physicians from the different medical specialties or in regard to gender. Nevertheless, with 14% of the respondents to our questionnaire being classified as either alcoholics or possible alcoholics, it appears that this is a pervasive problem in our profession that deserves further study.
Phlegmonous gastritis and Hemophilus influenzae peritonitis in a patient with alcoholic liver disease.
A patient with alcoholic liver disease and ascites had Haemophilus influenzae peritonitis and died in spite of vigorous antibiotic therapy. At autopsy, a phlegmonous gastritis was found as a likely cause of the peritonitis. Phlegmonous gastritis is an uncommon cause of unexplained gastrointestinal symptoms in alcoholics and in the elderly, and it may be pathogenetic in rare patients with bacterial peritonitis of unclear source.
Fever of unknown origin. The general internist's approach.
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Preserving renal function in surgical patients.
Postoperative acute renal failure, especially associated with oliguria, carries a high rate of mortality and morbidity. This complication can frequently be avoided if physicians are knowledgeable about preventable or modifiable risk factors. Patients who have underlying renal disease, sepsis, volume depletion or other conditions associated with renal hypoperfusion, or who have severe liver disease, are at particular risk. Exposure to nephrotoxic agents and wide fluctuations of intravascular volume are key conditions that can usually be minimized. Managing patients with chronic advanced renal failure (creatinine clearance 10 to 25 ml per minute) requires close interaction between the internists, anesthesiologists and surgeons. Understanding associated metabolic and organ system disorders is necessary to prevent complications and preserve remaining renal function. Chronic renal failure should not be a contraindication to an elective or emergent surgical procedure.
Stratification of prognosis in granulocytopenic patients with hematologic malignancies using the APACHE-II severity of illness score.
The APACHE-II (acute physiology and chronic health evaluation) severity of disease classification system was used to stratify prognosis of granulocytopenic patients with hematologic malignancies. A total of 146 admissions were retrospectively reviewed. In 26 ICU admissions, mortality was 69.2%; in 120 admissions to the ward, mortality was 15.8%. The APACHE-II score successfully stratified prognosis in both ward and ICU settings. Respiratory failure and the presence of pneumonia on chest x-ray were identified as poor prognostic factors. ICU patients admitted for monitoring or postoperative care had a better prognosis than those admitted for severe cardiopulmonary compromise. We suggest that the APACHE-II system is useful for stratifying prognosis for clinical research in this group of patients, although it remains to be shown whether it will be useful in predicting the prognosis of individual patients.
The therapeutic value of pets.
While domestic pets are capable of transmitting disease and inflicting injury, they may also be of benefit to human health. Studies suggest that companion animals, in addition to their well-known role as helpers to the handicapped, may alleviate depression, solace the lonely, facilitate psycho-therapy, socialize criminals, lower blood pressure, increase survivorship from myocardial infarction and ease the social pain of aging in our society.
Space-age snake oil. Obesity and consumer fraud.
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Survey on views and knowledge of house officers on medical-legal issues.
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Penetration of oral doxycycline into the cerebrospinal fluid of patients with latent or neurosyphilis.
Five patients with laboratory evidence of latent or neurosyphilis were treated orally with doxycycline (200 mg) twice a day for 21 days. After the seventh dose, the mean level of doxycycline in serum was 5.8 micrograms/ml, with a mean drug level in cerebrospinal fluid of 1.3 micrograms/ml. The mean penetration into cerebrospinal fluid was 26%. These preliminary findings suggest that doxycycline, administered orally at a dose of 200 mg twice a day, reaches a sufficient concentration in cerebrospinal fluid to be worthy of further evaluation as an alternative regimen to penicillin therapy for latent or neurosyphilis.
The classic venereal diseases. Syphilis and gonorrhea in the 80s.
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Trace metals in human disease.
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Science and scam: alternative thought patterns in alternative health care.
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