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Biomedical subjects

F Szubstarski

Publications and source records attributed to F Szubstarski.

At least 19 recordsLinked to original sources

Does the degree of cell lesion in breast cancer after inductive chemotherapy have any prognostic value?

During 1991 and 1992, 77 patients with breast cancer were treated with induction chemotherapy using the CMFV and FAC protocols at the Lublin Oncological Centre. The degree of cancer cell damage in the specimens obtained postoperatively was evaluated by microscopy. Complete or substantial damage of neoplastic cells was found in 29% of the cases; whereas minimal to no damage was found in 71% of specimens. After assessing the 5-year survival periods of our patients in relation to the degree of cancer cell damage after induction chemotherapy, a statistically significant correlation was noted. Five-year survival without cancer symptoms was observed in 64% of cases in which the cell damage was estimated as considerable, and only in 34% in which the damage was slight or not notable. A much weaker correlation was observed between the degree of breast cancer cell damage after inductive chemotherapy and clinical response.

Adult↗

[Angiofollicular lymph node hyperplasia (Castelman's disease) in an adult woman].

Angiofollicular lymph node hyperplasia Castleman's disease) is a rare disorder of unclear etiology and wide spectrum of systemic symptoms. This report describes a case of this disorder of hyalinovascular type in 45-years old woman. The lesions were localized in axillary lymph nodes. The disease was curable by surgical excision.

Castleman Disease↗

[Laryngeal cancer in siblings].

A rare case is described of laryngeal cancer in brother and sister. There have been as yet 21 similar cases in literature reports. The role of habits is discussed as well as certain familial proneness, rarely observed in this type of neoplasm.

Female↗

[Diagnostic difficulties in a case of polyarteritis nodosa].

A case of polyarteritis nodosa is presented in view of diagnostic difficulties which it caused. In a 47-year-old patient, in the clinical picture the following predominated: paroxysmal abdominal pain, symptoms and signs of polyneuropathy, and paralysis of the left peroneal and left radial nerves. Besides that, hypertension, tachycardia, sub-febrile states, significant body weight loss, and skin lesions were observed. In laboratory investigations high ESR, leucocytosis, HBe antigenaemia with the presence of all antibodies, and significant hypergammaglobulinaemia were found. In the differentiation, apart from polyarteritis nodosa, the following was taken into account: porphyria, neoplastic abdominal diseases with polyneuropathy, neurological diseases. Of decisive importance for making the diagnosis was microscopic examination of calf muscle biopsy specimen.

Biopsy↗

[Tuberculosis of the retroperitoneal lymph nodes].

The authors present an extremely rare location of retroperitoneal lymph node tuberculosis, imitating in ultrasonography and computed tomography a neoplastic tumour of this region. The diagnostic difficulties associated with the described case are analysed.

Diagnosis, Differential↗

[9 years' survival of a patient with malignant mesenchymoma].

The authors present diagnostic and therapeutic documentation of a very rare case of a tumour with mesenchymoma malignum texture in a 48-year old woman operated because of uterine myomas. After the surgery (total hysterectomy and adnexectomy by Freund procedure) followed by radiotherapy and chemotherapy, the patient survived nine years. At the bottom of the therapeutic success lies incidental very early discovery of the tumour and combined treatment of this kind of sarcoma, extremely malignant, thanks to operative therapy of uterine myomas.

Female↗