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Biomedical subjects

F Shishido

Publications and source records attributed to F Shishido.

At least 145 records · Page 8Linked to original sources
PubMed1980

[Clinical study of adrenal imaging with 123I-labeled-6 beta-iodomethyl-19-norcholesterol (author's transl)].

Although adrenal scintigraphy with 131I-6 beta-iodomethyl-19-norcholesterol (NCL-6-131I) was used for the first noninvasive imaging of the adrenal glands, it has the disadvantages. These are: (i) relatively high radiation dose to patients, (ii) the long time required for completion of the scan. To solve these problems, 123I-labeled 6 beta-iodomethyl-19-norcholesterol (NCL-6-123I) was synthesized and was used for adrenal scintigraphy in 6 cases. Successful images were obtained with 185 MBq (5 mCi)-260 MBq (7 mCi) of NCL-6-123I, and optimal time required for the satisfactory scan was 2-3 days after the administration. The estimate radiation dose was reduced by using 185 MBq (5 mCi) of NCL-6-123I instead of 18.5 MBq (0.5 mCi) of NCL-6-131I. From the result of this clinical study, NCL-6-123I was preferred for the adrenal scintigraphy.

Adosterol↗
PubMed1978

[The upper gastrointestinal imaging and the gastrogram using 99mTc-pertechnetate (author's transl)].

99mTc-pertechnetate was used for the diagnoses of the upper gastrointestinal tract. Oral administration was useful for the detection of the stenosis and obstruction on the esophagus and the pylorus to the poor risk patients. Mucosal imaging of the stomach was clearly revealed by intravenous administration, and the scintigram of the patient with stomach cancer showed a cold region. Taking the gastric scintiphoto, temporal radioactivity in the stomach region was recorded (gastrogram). This seems to be a new and prospective approach to the clinical gastroenterology.

Administration, Oral↗
PubMed1978

Semiquantitative 67Ga scanning of lung cancer by scintiscoring: its usefulness in diagnosis of localization, therapeutic effectiveness, radiation pneumo-mediastinitis and recurrence.

Attempts were made to attain a semiquantitative evaluation of therapeutic effectiveness of lung cancer by scintiscoring of the liver as well as the tumor lesion. A relative counting ratio of tumor to liver was computed, and this was found useful: in areas of active tumorous growth, higher ratios were obtained. The ratios returned to the control levels following irradiation with or without an anti-inflammatory regimen including prednine. The technic is simple, and yet invaluable especially when the tumor locates in the mediastinum escaping from radiological detection. Satisfactorily frequent repetition would be competent enough in early diagnosis of developing radiation pneumo-mediastinitis and regrowths in the mediastinum and fibrotic abnormal shadows as well. The principle would be best rewarded by use of a whole-body scanner equipped with a digital computer.

Evaluation Studies as Topic↗