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Biomedical subjects

F Scheutz

Publications and source records attributed to F Scheutz.

102 records · Page 6Linked to original sources

Saliva secretion rate in a group of drug addicts (short communication).

Stimulated saliva secretion rate was measured in 40 parenteral drug addicts who had a preference for opiates. Illicit drug abuse or intake of legally prescribed medicine within the last 24 h were recorded. Mean saliva secretion rate for the whole group of drug addicts was 1.51 ml/min with no statistical difference from a control group (P greater than 0.30). However, drug addicts who had taken legally prescribed tranquillizers or sedatives had a reduced saliva secretion rate (1.01 ml/min), whereas no decrease was found among the individuals who had taken opiates within the last 24 h (1.42 ml/min, P greater than 0.10).

Adolescent↗

Viral hepatitis among parenteral drug addicts attending a Danish addiction clinic.

100 parenteral drug abusers attending an addiction clinic were studied for past or present infection with hepatitis A and B virus (HAV and HBV) by sensitive serological assays for hepatitis B surface and e-antigen and antibodies to HBsAg, HBeAg, HBcAg and HAV. 44% of the individuals had past HAV infection, which is 4 times as high compared to the general population in Denmark. 83% had evidence of past or present HBV infection with no difference between men and women. This is 30 times higher than in the general population in Denmark. 18% of the subjects studied were positive for HBsAg and/or anti-HBc alone, but only 3 of these were positive for HBeAg (3%). Serum transaminase values were often elevated but this finding could not differentiate between patients with or without HBV infection. Infection with HBV appeared to take place during the first year of the drug addict's career, and to eliminate this major reservoir of HBV infection the main objective will be to prevent new susceptible individuals in getting addicted.

Adolescent↗

Drug addicts and local analgesia--effectivity and general side effects.

The frequency of successful analgesia and the frequency of general side effects during dental treatment of previous and present drug addicts were investigated in a controlled clinical study. A solution of xylocaine/adrenaline (20 mg/ml + 12.5 micrograms/ml) was used in a dose of 1.5 ml for 88 mandibular blocks in order to test the frequency of analgesia. Successful analgesia was recorded only if the patient experienced no pain in the operative area. The number of side effects such as unrest, anxiety, sweating, pallor and palpitation was recorded during another part of the study. The frequency of successful analgesia was lower among the previous and present drug abusers compared to the control group and the difference was statistically significant. A statistically higher number of side effects was recorded in both experimental groups. The need for a higher dosage of local analgesic and the higher number of side effects is attributed to the fear and anxiety among this particular group of patients. In the light of these findings the significance for the management of drug addicts during dental treatment is discussed.

Adolescent↗