[Controlled study on the efficacy of external treatment in surface-near thrombophlebitis].
The efficacy of an organo-heparinoid ointment (Hirudoid 40,000) compared with a placebo ointment was tested in a double blind trial on 40 patients with post-operative infusion thrombophlebitis. It was possible to provide objective data by means of the 125I-fibrinogen test for accelerated regression of thrombi following treatment with organo-heparinoid. The differences found between the 2 treatment groups were statistically significant. The clinical results conformed largely to the measured data. Especially pain and swelling were favourably affected by treatment with the active compound. 1 case of local allergic reaction to organo-heparinoid was observed. No further side-effects were seen.
Drug Evaluation↗