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Biomedical subjects

F Sato

Publications and source records attributed to F Sato.

At least 397 records · Page 22Linked to original sources
PubMed1983

Cerebral angiographic changes on serial examination of a patient with migraine.

Curious cerebral angiographic changes are described in a 27-year-old female migraine patient. During the period of observation of this patient, both the intracranial carotid artery and the vertebrobasilar artery systems presented unusual and fascinating cerebral arteriographic pictures. In an attack of migraine, angiography showed that all the intracranial secondary and tertiary branches of the carotid arterial system were dilated without showing any changes in the extracranial arteries and when the migraine attack had subsided, all branches of the carotid arteries as well as the vertebrobasilar arteries demonstrated abnormal segmental narrowings or vasospasm. These sequential angiographic changes have not been hitherto reported in migraine.

Adult↗
PubMed1983

Trigeminal neurinoma revealed by intratumoral hemorrhage following a minor head injury.

A trigeminal neurinoma which produced the signs and symptoms of a localized intratumoral hemorrhage without showing any extratumoral hemorrhage successive to a minor head injury is reported here. A 33-year-old man noticed pain and hypesthesia on the right side of the forehead and double vision on the day following an occipital trauma. A computed tomographic scan demonstrated a large high-density mass in the anterior part of the right cerebellopontine angle. A diagnosis of trigeminal neurinoma was made and the tumor was successfully removed. The largest part of the tumor consisted of a blood clot and necrotic tissue. In this case of minor head injury, the intratumoral hemorrhage was thought to have occurred as a result of obliteration of the lumen followed by recanalization of the meningeal vessels enclosed in the tumor by the growing neurinoma and distal vessel necrosis. Such a case of trigeminal neurinoma which revealed itself through intratumoral hemorrhage following a minor head injury has not been previously reported.

Adult↗
PubMed1983

The enzyme histochemistry of the choroid plexus.

Although there is some evidence that extrachoroidal sites for the production of cerebrospinal fluid (CSF) are important, the choroid plexuses in the ventricles contribute the major part of CSF formation. The exact mechanism for CSF production is not fully understood. In order to study this mechanism from the enzyme histochemical standpoint, the previously reported studies are reviewed, in addition to the authors' own electron microscopic enzyme histochemical observations on this tissue. The ultrastructure and enzyme biochemistry of choroid plexus epithelial cells are considered, together with the histochemistry of the following enzymes: alkaline and acid phosphatase, Mg2+-ATPase, Na+, K+-ATPase, glucose-6-phosphatase, thiamine pyrophosphatase, adenylate cyclase, carbonic anhydrase, oxidoreductase, esterase, several hydrolases, and other enzymes. Finally, CSF formation and active transport in the choroid plexus epithelial cells are discussed, mainly in terms of the results of our enzyme cytochemical observations on Na+, K+-ATPase and carbonic anhydrase in this tissue.

Animals↗
PubMed1983

Cholinergic potentiation of isoproterenol-induced cAMP level in sweat gland.

Although methacholine (MCh) and a Ca2+ ionophore A23187 do not enhance the tissue adenosine 3',5'-cyclic monophosphate (cAMP) level by themselves, they markedly potentiate isoproterenol (ISO)-induced tissue cAMP accumulation in isolated simian eccrine sweat glands in a dose-dependent manner. The agonist concentration producing 50% of the maximal response of such a potentiated cAMP accumulation was 2.1 X 10(-7) M for MCh, 2.5 X 10(-7) M for ISO, and 2.9 X 10(-6) M for A23187. Unlike cAMP accumulation induced by ISO alone, MCh-stimulated ISO-induced cAMP accumulation is dependent on extracellular Ca2+. MCh- plus ISO-induced cAMP level is tripled by 10(-2) M theophylline (TH), and while the ISO-induced cAMP level was also elevated by TH, it was not enhanced to the level of ISO-plus MCh-induced cAMP accumulation, indicating that phosphodiesterase inhibition is not the major mechanism for the augmentative effect of MCh. The augmentative effect of MCh was seen only in the secretory portion, whereas that of A23187 was seen in both the secretory portion and the duct. The data suggest that MCh-induced augmentation of ISO-stimulated cAMP accumulation is due to increased cAMP formation, not decreased cAMP degradation, and that it may be mediated by an elevated intracellular Ca2+.

Animals↗
PubMed1983

Individual variations in structure and function of human eccrine sweat gland.

The mechanisms underlying variations in perspiration rate at the glandular level are still poorly understood. Human eccrine sweat glands were dissected from the back of 12 adults, cannulated, and stimulated in vitro with methacholine (Mch). The maximal sweat rate and pKA for Mch determined from the dose-response curve for each individual were compared with the anatomic dimensions of the isolated secretory tubules. There was significant correlation between Mch sensitivity (pKA) and the size of the sweat gland, sweat rate per gland, sweat rate per unit length of the secretory tubule, and sweat rate per unit glandular volume. The sweat glands from individuals judged to be poor sweaters exhibited smaller size, lower secretory activity both in vivo and in vitro, and decreased Mch sensitivity compared with glands from physically fit individuals. We conclude that the increased Mch sensitivity and glandular hypertrophy are the two important features of functionally active sweat glands and infer that these parameters could improve as a result of acclimatization to physical exercise and/or heat.

Adult↗
PubMed1983

Primary monolayer culture of rat ependymal cells: an ultrastructural study.

Dissociated cerebella of newborn rats were cultured in vitro as a monolayer for a long period, and ependymal cell differentiation was investigated by scanning and transmission electron microscopy. Cells with actively beating cilia were recognized on the 3rd day, and gradually increased in number thereafter. At nine months of culturing, a number of areas appeared, some of which consisted of several hundreds of ciliated cells. Cultured ependymal cells showed a striking resemblance in their fine structure to the intact ependyma. They were always found to grow upon the feltwork of astrocytic processes which served as a subependymal structure, as observed in the intact ependyma. It is possible that astrocytes may play some role in ependymal differentiation. Cultured ependymal cells are helpful in understanding the control mechanism for the metachronal cilial movement.

Animals↗
PubMed1983

Intraventricular cavernous hemangioma. Case report.

A case of intraventricular cavernous hemangioma in a neonate is reported. In over 200 previously reported cases of intracranial cavernous hemangioma, 11 histologically verified cases have been collected and analyzed. The present case is the second occurring in a neonate.

Cerebral Ventricle Neoplasms↗
PubMed1983

[Clinical studies of cefotiam in otorhinolaryngologic infections].

Cefotiam (CTM) was intravenously given to 12 patients with infectious diseases in the field of otorhinolaryngology including 10 cases with chronic suppurative otitis media. Daily doses of CTM were 1 to 4 g. Clinical responses were excellent in 3 patients, good in 5, fair in 1 and poor in 3. The rate of overall clinical effectiveness was 67%. Staphylococcus species were most frequently isolated from the patients and all of them were eradicated by the CTM treatment. No side effects and no abnormal laboratory findings relating to the drug administration were observed.

Adolescent↗
PubMed1982

The localization of the motor neurons innervating the cricothyroid muscle in the adult dog by the fluorescent retrograde axonal labeling technique.

Injection of 4'6-diamidino-2-phenylindol 2 HCl (DAPI) into the cricothyroid muscle of the adult dog resulted in blue fluorescence of cells found exclusively in the rostral part of the ipsilateral nucleus ambiguus. These labeled neurons on the average extended 1.8 mm from the level just caudal the facial nucleus to the caudal extension. In the rostral tip of the nucleus, labeled cells were located in a scattered ventral group of larger neurons of the nucleus.

Animals↗
PubMed1982

The development of intracranial aneurysms associated with pulseless disease.

Two cases of pulseless disease associated with intracranial aneurysms, one located at the tip of the basilar artery and the other at the left internal carotid-posterior communicating artery junction which developed with episodes of subarachnoid hemorrhage due to their rupture, are presented. Whether the aneurysms and pulseless disease occurred independently or whether the aneurysms developed secondarily from the altered hemodynamic flow produced by pulseless disease is unknown; however, it is certain that abnormal intracranial hemodynamic forces play a role in the development of aneurysms.

Adult↗