[The course of infectious bronchopulmonary complications during polychemotherapy for bronchogenic carcinoma in immunodepressed patients].
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Adult↗
Biomedical subjects
F Salvati
Publications and source records attributed to F Salvati.
[The Pelger-Huet granulocytic anomaly: first report of 2 homozygous subjects in the same family].
Pelger-Huet granulocyte anomaly is characterized by the presence of granulocytes with a non segmented nucleus and thick nuclear chromatin gathered in large lumps. In human we known two forms of the anomaly: the heterozygous form often described by many authors, and the homozygous form, very rare. With regard to morphology, the homozygous form is characterized by granulocytes with round nucleus and very coarse chromatin. In this report the presence of two homozygous carriers of the anomaly in the same family is discussed.
Aged↗
Combined treatment with thymosin-alpha1 and low-dose interferon-alpha after ifosfamide in non-small cell lung cancer: a phase-II controlled trial.
22 patients with advanced non-small-cell lung cancer were randomized to receive chemotherapy (ifosfamide) or chemotherapy followed by thymosin alpha1 + low-dose IFNalpha. Chemo-immunotherapy induced an enhanced response rate compared with chemotherapy alone (33% and 10% respectively). Although these differences were not significant, the difference in time to progression was (p=0.0059). CD4+, CD8+ and NK cell counts were significantly depressed after two cycles of chemotherapy, while no difference in cell count were seen in chemo-immunotherapy treated patients. Hematologic toxicity was reduced by the immunotherapy, with no grade 3/4 toxicity seen compared to 50% in patients treated with chemotherapy alone.
Adenocarcinoma↗