Biomedical subjects

F Sacco

Publications and source records attributed to F Sacco.

At least 19 recordsLinked to original sources

PubMed1990

[Transvaginal estrogen therapy in urinary stress incontinence].

Thirty-four postmenopausal stress incontinence patients were divided in two groups: 17 were treated with 0.5 mg oestriol vaginal cream for 90 days, 17 controls were treated with moisturizing cream. All had low urethral pressures and dystrophy. Treated patients showed improvement of maximum urethral pressure, urethral closure pressure, and volume at first sensation of fullness. Dystrophy was cured in most patients; in 17% incontinence was cured and in 41% subjectively improved.

Estriol↗

PubMed1988

[Blood folates in pregnancy and therapy with high-dose folinic acid].

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Female↗

PubMed1984

Platelet activation in patients with benign and malignant ovarian diseases.

Plasma concentration of beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) were measured by radioimmunoassay in 45 patients with benign and malignant ovarian diseases. All patients with ovarian carcinoma showed increased beta-TG and PF4 levels. Among benign ovarian diseases the patients with serous cystadenoma more frequently showed signs of platelet activation, whereas those with endometriotic cyst and mucinous cystadenoma generally had normal beta-TG and PF4 values. These results indicate that an increased platelet activation is consistently associated with malignant tumors of the ovary, whereas benign tumors show a different capacity to induce platelet activation.

Adult↗

PubMed1982

["In vivo" and "in vitro" immunological monitoring in carcinoma of the uterine cervix].

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Carcinoma↗

PubMed1981

The treatment of 48 patients affected by ovarian carcinoma at stages III and IV F.I.G.O.

The Authors analyzed the treatment of 28 patients in stage III (FIGO) and 20 patients in stage IV affected by epithelial ovarian cancer. In these cases, surgery was based on the criterion of cytoreduction and, where possible, maximum radicality. Within a month from surgery, all patients underwent a program of combined chemotherapy (VCR + 5 FU + CTX) envisaging successive cycles, every four weeks. Minimal side effects were generally observed. 13/28 (46.4%) responses were recorded in stage III and 4/14 (28.6%) in stage IV. The highest percentage of responses, 80%, was obtained in patients with a residual tumor less than 2 cm, all belonging to stage III. Stage III and stage IV patients with a residual tumor greater than 2 cm responded in 45% and 33% of the cases respectively. Patients who underwent explorative laparotomy showed negligible responses. There was a statistically significant difference survival between stage III and stage IV patients (p less than 0.001), among patients with a similar residual tumor greater than 2 cm, but in different stages (p less than 0.05), and among stage III patients who responded or not to chemotherapy (p less than 0.001).

Adenocarcinoma, Mucinous↗

PubMed1981

Sertoli cell adenoma in Morris syndrome.

An unusually large Sertoli cell adenoma was detected in a patient with Morris syndrome and there is a description of the uncommon hormonal data found in this particular case which are not typical for this kind of neoplasia. The patient is alive and well at the present time which is now three years after surgical intervention.

Androgen-Insensitivity Syndrome↗

PubMed1981

Sertoli cell adenoma in Morris syndrome.

Androgen-Insensitivity Syndrome↗

PubMed1981

Urinary diversion by ileal conduit in gynecologic oncology.

In the decade 1967-1977, 663 patients with different gynecologic neoplasms were admitted and treated at our Department. Because of the involvement of the urinary tract, urinary diversion was required in 41 cases. Ileal conduit was performed in 25 patients (20 affected by carcinoma of uterine cervix, 4 by adenocarcinoma of endometrium, 1 by carcinoma of vulva). In 19 patients such procedure was performed immediately after radical surgical therapy; in 6 patients ileal conduit was indicated because of post irradiation fistulas. Few complications were observed and all of them successfully cured. Authors conclude that Bricker operation is still an effective procedure in gynecologic oncology, both as a complement to radical surgery (in selected patients), and as a complementary treatment of recurrences and complications of radiation therapy.

Adenocarcinoma↗

PubMed1980