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Biomedical subjects

F S Chew

Publications and source records attributed to F S Chew.

At least 127 records · Page 7Linked to original sources
PubMed1991

Radiologic manifestations in the musculoskeletal system of miscellaneous endocrine disorders.

The manifestations of endocrine derangements in the musculoskeletal system in infancy and childhood are disturbances in growth and maturation and in adulthood are disturbances in maintenance and metabolism. Hypercortisolism during skeletal immaturity suppresses growth. In the adult, hypercortisolism leads to osteoporosis, osteonecrosis, and muscle wasting. Deficiency of growth hormone during skeletal development results in short stature. An excess of growth hormone in a skeletally immature individual results in gigantism, an excess in a skeletally mature individual results in acromegaly. Patients with gigantism have extreme height with normal body proportions. Musculoskeletal manifestations of acromegaly include soft-tissue thickening, vertebral body enlargement, characteristic hand and foot changes, and enthesal bony proliferation. Hyperthyroidism causes catabolism of protein and loss of connective tissue, which manifest as muscle wasting. Deficient levels of thyroid hormone cause defects in growth and development. Severe growth retardation from congenital hypothyroidism is rare because neonatal screening recognizes the disorder and leads to early treatment. The skeletal manifestation of hypergonadism in children is precocious growth and early skeletal maturation. Although the initial precocious growth spurt results in a tall child, early closure of the growth plates results in a short adult. Hypogonadism in the prepubertal child results in delayed adolescence and delayed skeletal maturation. Diabetes mellitus in childhood results in decreased growth, a phenomenon presumed to be secondary to nutritional abnormalities. Generalized osteoporosis and short stature are common. In the adult, generalized osteoporosis may accompany insulin-dependent diabetes mellitus if obesity is absent. Calcification of interdigital arteries of the foot is common in diabetics and uncommon in other conditions. Additional skeletal manifestations relate to complications of diabetes such as peripheral neuropathy and diabetic foot disease.

Adult↗
PubMed1990

Advanced microcomputer-aided medical illustration.

In a visually oriented field such as diagnostic radiology, illustrations, diagrams, and other types of art-work can complement verbal description and photographs, simplify the description of anatomic concepts, and add interest and aesthetic value to a presentation or manuscript. The vast potential of the microcomputer for creating high-quality art and graphics is being realized by the availability of high-level illustration programs running on fast computer systems. Advanced microcomputer applications for illustration have the tools to compose and execute drawings of virtually unlimited detail and complexity. Digitized images can be used as drawing templates or as components of finished art. Text is easily incorporated. Each individual element of a drawing can be changed or edited without altering other portions of the drawing. finished art can be output to laser-xerographic printers, film recorders, and photo imagesetters.

Computer Graphics↗
PubMed1988

Gastrostomy tube pancreatitis.

Acute pancreatitis developed in a child following inadvertent placement of a gastrostomy tube balloon in the descending duodenum. After a gastrostomy tube is inserted, radiologic confirmation of correct tube position is recommended to help avoid this rare iatrogenic complication.

Acute Disease↗
PubMed1988

How research becomes knowledge in radiology: an analysis of citations to published papers.

The process by which research becomes generally disseminated knowledge in radiology was studied by an analysis of reference citations. A citation is the event that occurs when one paper is listed as a reference by another paper. Analysis of the citations received by 30 diagnostic radiology journals in 1985 showed that five journals received 73% of the citations. Approximately half of the citations were made to papers over 5 years old. Analysis of the citations received by the 1977 issues of eight journals over a 9-year period showed a rapid rise in the number of citations received, a peak in the third year after publication, and a slow, exponential decline. Analysis of citations to a group of individual papers showed that 10% of the papers received nearly 50% of the citations. This information suggests that citations to the radiology literature are concentrated among a handful of papers in a few journals. The citation activities of individual journals reflect in part their editorial policies. Parameters of citation activity may be relevant to selecting journals for subscription, reading, or publication. The radiology literature has lasting relevance and receives citations for many years. Advancement of the science of radiology follows the lead of a very few works; the most frequently cited papers concern practical techniques and procedures.

Periodicals as Topic↗
PubMed1987

The continuum of pulmonary developmental anomalies.

The classic features of six common pulmonary developmental anomalies have been presented. In addition, several overlap cases, each demonstrating features of more than one anomaly, have been illustrated. Such cases serve to emphasize that pulmonary developmental anomalies exist as a continuum, often frustrating our attempts at discrete classification. Future advances in pulmonary embryology may further elucidate the pathogenesis of these entities.

Adult↗
PubMed1986

The scientific literature in diagnostic radiology for American readers: a survey and analysis of journals, papers, and authors.

The scientific literature in diagnostic radiology for American readers was surveyed by studying the recent growth of its journals, papers and authors. The number of journals has increased rapidly, following the growth in the production of papers. Of the 36 scientific diagnostic radiology journals available at a university medical center, 18 began publication in 1973 or later. The proliferation of new journals should moderate as the size of the American diagnostic radiology research community stabilizes and the newer journals publish a growing share of the papers. Citation analysis, a method of studying interrelationships between papers and journals, showed that citations from papers published in clinical journals to papers published in diagnostic radiology journals accounted for 6% of total citations made in those clinical journals. This observation indicates that research in diagnostic radiology has considerable relevance to research in clinical medicine. Although the number of papers from American diagnostic radiology researches increased from 468 papers in two journals in 1960 to 2861 papers in 16 journals in 1984, the number of researchers increased more rapidly, resulting in a decline in aggregate productivity. At the same time, the average number of authors per paper increased from 2.15 in 1960 to 4.36 in 1985. The first authorship of a scientific paper appears to be the most suitable quantitative measure of research productivity. Study of a sample of 130 diagnostic radiology researchers showed that, on average, each researcher published 3.8 papers as first author in the 5 years from 1980 to 1984. The most prolific 15% of the authors published 52% of the papers.

Authorship↗