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Biomedical subjects

F Rusticali

Publications and source records attributed to F Rusticali.

At least 19 recordsLinked to original sources

[Doppler ultrasound in the diagnosis of renal artery stenosis in hypertensive patients: a prospective study].

Renal artery stenosis is the most common surgically or interventionally curable cause of hypertension. Screening and diagnostic tests are still needed to establish the presence of renal artery stenosis. The aim of our study was to evaluate sensitivity, specificity and diagnostical accuracy of renal artery duplex scanning for diagnosis of renal artery stenosis in hypertensive patients. Between January 2, 1988 and December 31, 1989 we performed renal artery duplex scanning in 128 hypertensive patients in whom were present clinical data suggestive of renal artery stenosis. Angiographic evaluation was performed within 3 months in 23 patients with a positive duplex, and in 15 patients with a negative duplex but highly suggestive for renal artery stenosis clinical data. Studies were performed with an Ultramark 8 duplex scanner (ATL). Data of this report are relative to the analyses performed of 76 renal arteries. Duplex scanning had a sensitivity of 90% and specificity of 96% to detect renal artery stenosis. Diagnostic accuracy was 93% for 50% to 60% stenosis and 100% for occlusion or 60% to 99% renal artery stenosis. Duplex scanning for diagnosis of renal artery stenosis shows agreement with angiography. Duplex scanning, which can distinguish high grade stenosis from occlusion, is able to select patients for possible percutaneous transluminal angioplasty before angiography, and we consider duplex scanning a valid, noninvasive screening or diagnostic test for renovascular hypertension.

Adult

[Comprehensive computer-assisted management of a cardiology department].

We are proposing a personal computer local network system for collecting data and managing of both cardiovascular in- and outpatients. The six PCs used as work stations are located in the following areas: reception desk, ergometry, holter, echocardiography, secretarial and coronary care unit and cardiology department. Starting from a commercially available DBMS program, an "Iceberg" applied program was first made in a single personal computer and then transferred to a local network. The tree-structured data base includes the cardiopathies list, the vasculopathies list, some cardiovascular clinical data and all information regarding cardiological instrumental tests. The data are descriptive, numeric, date, text and comment. The operative program allows us to change the data base without the help of the software house staff, so the system is adaptable to cardiological departments with different instrumental equipment and sections. The report of instrumental tests and the issuing of the discharge letter are made with the local work station, with simultaneous compiling, storing and printing. It is then possible, using any work station, to restore and print quickly a summary of all data concerning each patient. This summary permits us, in nearly all cases, to identify the patient's history and present condition, as well as the diagnostical steps taken.

Cardiology

Doppler hemodynamic characteristics of four widely used aortic valve prostheses.

Fifty-one patients with normofunctioning aortic prosthetic heart valves were evaluated by Doppler-Echocardiography to determine type-related flow characteristics. The four mechanical valves tested were: Starr-Edwards (1200-1260 aortic), Bjork-Shiley (60 degrees-60 degrees cc aortic), Medtronic-Hall (aortic) and St. Jude Medical (aortic). The most significant dynamic indexes were calculated: Peak (PG) and Mean (MG) Gradient across the valve, Cardiac Index (CI) or Cardiac Output (CO), Regurgitant Jets, Effective Orifice Area (EOA), Spectral Diagram Systolic Trend (SDST) and PVRT (time required to reach peak velocity during systole)/LVET (left ventricular ejection time) Ratio. Patients with Doppler assessed prosthetic dysfunction were dropped out of the study group. As expected, significant reverse correlation (-0.70) was found when transvalvular pressure gradients were compared with valve size. Significant direct correlation (0.82) was found when EOA was compared with valve size, thus suggesting the high reliability of the continuity equation in the assessment of the real orifice area. The Starr-Edwards valve, when compared with the other prostheses of the same size, showed the highest calculated transvalvular gradient; the St. Jude Medical showed the lowest. On the other hand, the Starr-Edwards valve was not commonly associated with regurgitation, while the St. Jude valve was usually moderately incompetent. Those hemodynamic differences should guide the selection of the ideal prosthetic valve for elective surgical indications. Doppler measurements provided noninvasive information similar to that given by cardiac catheterisation, which was reproducible and specific for valve function. According to this high sensitivity and specificity and to the absolute innocuity of the procedure, Doppler-Echocardiography should be considered the elective technique for long-term follow-up in patients with aortic prosthetic heart valves.

Adolescent

[Value of metabolic studies in diagnosis of ischemic cardiopathy].

10 patients with documented heart disease were undergone to atrial pacing (AP) combined to metabolic study. A negative lactate utilization (-%L) noticed in SC (coronary synus) represents a sure proof of a subordinate pacing ischaemia. As the negative lactate utilization is absent a significative reduction of %L during AP or its persistence in recovery and a rise of L/P are further parameters of a subordinate pacing ischaemia. The Authors consider the usefulness of combining a metabolic study to AP in assessing the RC (coronary reserve).

Angina Pectoris

[Electrophysiological evaluation of the aberrant pathways of intraventricular conduction obtained by means of premature atrial stimulation].

12 patients with normal QRS either in basal condition or during atrial pacing, undergone on single premature atrial stimulation, showed several types of intraventricular aberrancies. These have been revalued with atrial premature stimulation introduced over a progressively increasing frequency of fixed atrial stimulation (extrastimulus method), sometimes after atropine. In 9 cases it was possible to eliminate completely the above mentioned aberrancies, having thus a clear reduction of the refractory periods regarding their responsible structures. In 3 cases this was not possible, owing to a less significant reduction of the refractory periods. Such fenomenon is considered as the only parameter able to identify probable initial organic facts of the His-Purkinje system.

Adult

[Transitory malfunction of an L-Kaster mitral prosthesis. Echocardiographic and polygraphic study].

An unusual instance of transient prosthesis breakdown in a 29-yr-old woman with two L-Kaster disk prostheses for mitro-aortic defect is reported. The ECHO and polygraphic traces observed during and after breakdown are examined. It is considered that the breakdown which occurred in one prostheis only, was attributable to a small, internal thrombosis with embolism of the right lower extremity.

Adult

[Rapid atrial stimulation in therapy of atrial flutter].

Personal experience in 12 cases of atrial flutter treated with various types of atrial electrostimulation is reported. In 6 cases the sinusal rhythm was obtained immediately. In the remaining cases sinusal rhythm was also obtained with atrial fibrillation from a minimum of 2 minutes to a maximum of 48 hours.

Adult

[Recording of the potential of the bundle of His through the veins of the arm].

A new technique for recording His bundle and right branch potential through the veins of the arm instead of by the femoral route is described. Recordings were carried out in 70 patients. In 10, His potential was recorded simultaneously by the femoral and brachial routes. Potentials proved to be similar as regards morphology and duration; A-V conduction time proved identical while there were slight variations in His node conduction time since the atriogram revealed varying intrinsic deflexions. It is thus possible to confirm that the recording of His potential by the brachial route offers various advantages: 1) it takes less time than the femoral route; 2) it is an excellent alternative if, for various reasons, the patient cannot be examined by the femoral route; 3) His potential can be monitored more easily because of the greater stability of the catheter and the provisional electrosimulation using the same catheter when necessary; 4) contemporaneous recording of right branch and His bundle potential is possible in association with the femoral technique with better results than those obtained using multipolar catheters; 5) it is without complications: i.e. the phlebitis, phlebothrombosis, a-v fistula, and pulmonary emboly which, however rarely, may occur when using the femoral route.

Arm

[Evaluation of the parameters concerning the method for determination of the sinus node recovery time. Personal experience (author's transl)].

On the basis of the personal experience of 36 patients with sick sinus syndrome, the role of length, seat, frequency of atrial stimulation (AS) on the duration of correct sinus node recovery time (CSNRT) were examined. The length of AS has little importance for values over 2 minutes. In 2 cases the CSNRT were pathological only if the position had been changed from the lateral wall of the right atrium to the middle right atrium. The frequency of AS is very important for the duration of pathological and maximal CSNRT. Therefore it is better to give every patient the major range of frequencies of AS as for a correct quantitative determination of sinus dysfunction so as not to lose some falsely negative results.

Arrhythmia, Sinus