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Biomedical subjects

F Rudello

Publications and source records attributed to F Rudello.

2 recordsLinked to original sources

Dynamic beam modulation by using a single computer-controlled absorber.

The authors have developed an apparatus able to generate ID intensity-modulated beams, using only one moving absorber within the irradiation field. A procedure for deriving optimized absorber-speed profiles in order to produce the desired fluence/dose profiles has been suggested. Experimental tests show that the system should be sufficiently reliable in reproducing modulated beam profiles of different shape: expected relative doses against measured relative doses have been found to be in agreement in a number of situations within 3% using a nonfocused device. A better agreement should be expected using a focused apparatus (which is currently being developed). Beam modulation by single absorber cannot modulate the beam fluence in any was one wishes, due to physical constraints, which depend on the absorber and field widths and on the shape of the desired fluence profile. However, the authors show that this simple and low-cost tool could offer, with a sufficient degree of accuracy, the possibility of modulating the beam fluence with a high degree of versatility. In particular, a procedure or performing tissue-missing compensation by single-absorber dynamic beam modulation is suggested. Moreover, 'strongly' modulated beam profiles can be created, showing that this simple technique could also have some interesting applications in the field of conformal radiotherapy by non-uniform dose delivery.

Algorithms

New compartmental model approach to dialysis.

Compartmental models are used for solving the problem of the control of dialysis therapy. The inadequacy of the existing monocompartmental model is faced, first with a careful analysis of the physiology of the system, then with a method focused on the construction of a new multicompartmental model. Moreover, impedance techniques allow us to solve the problem of measuring the total body water for each patient.

Body Water