Search PubMedSearch

Biomedical subjects

F Roth

Publications and source records attributed to F Roth.

At least 19 recordsLinked to original sources

[Benefits and side effects of preoperative autologous blood donation in 11 heart surgery patients].

Patients scheduled for cardiac surgery are prone to adverse reactions during blood donation due to hemodynamic instability. 11 selected patients donated three units of red blood cell concentrates and three units of fresh frozen plasma (FFP) preoperatively in 11-day intervals under careful hemodynamic monitoring. 24 hours preoperatively autologous plasmapheresis (500 ml) was carried out in 10 patients at bedside. No complications were seen in any patients. The patients' mean hemoglobin concentrations were 142 +/- 11, 133 +/- 6, 128 +/- 7 and 126 +/- 7 g/l (mean +/- 1 SD) before each autologous blood donation and before the plasmapheresis respectively. No significant changes were noted in major hematological and chemical screening tests. Serum iron, iron-binding capacity and ferritin levels remained within the normal range. Due to additional perioperative blood saving methods, such as reinfusion of centrifuged oxygenator-blood (559 +/- 119 ml) and shed mediastinal blood (518 +/- 353 ml), only two patients needed additional transfusion of 1 homologous red cell unit each. On average 2.18 autologous red cell concentrates were retransfused per patient.

Blood Chemical Analysis

[Intrahospital transportation in large hospitals].

In July 1989 an enquiry was conducted among all intensive care units with more than 6 beds regarding their experience of intrahospital transport of critically ill patients. The results are presented and commented on. The study then deals with some of the specific problems which arise when critically ill patients have to be moved within the hospital. Recent publications and our own experience concerning transport of ventilator-dependent patients suggest that there should at least be monitoring of expiratory volumes. Ventilation of the patient by portable mechanical ventilator has proven superior to manual ventilation since mechanical ventilation is more consistent and therefore fewer hemodynamic complications are to be expected. A simple device is described involving suction (by means of an injector run on oxygen) and an oxygen delivery system including an outlet into which the respirator can be plugged direct. A small shelf which can be easily attached to the bed has proven helpful during transport.

Continuity of Patient Care

[A hemagglutination inhibition test for control of the quality and effectiveness of highly-purified C. chauvoei toxoid vaccine].

To control quality and efficiency of a highly purified C. chauvoei vaccine which has been developed in Göttingen a haemagglutination-inhibition test is presented. Laboratory and field trials did demonstrate the value of the test. Vaccinated guinea pigs which presented positive HIT titers survived the challenge. Cattle, vaccinated with the vaccine in Germany, Madagascar and Mexico showed positive titers which could be boostered through repeated vaccination.

Animals

[Cast composite veneers].

No matter the reason, patients will no longer tolerate any malformation or staining of anterior teeth. One can not ignore the fact, that with time, esthetics and a pretty smile have become important issues for most individuals. When indicated and properly placed, composite veneers can probably rectify these situations (at least as a temporary measure due to their moderate cost and the minor amount of tissue which has to be destroyed). Professor Françoise Roth, who was one of the first individuals to study this procedure, allows us to profit from her experience with the assistance of Doctor Michel Gouvernet.

Composite Resins

Prophylactic treatment of acute gastroduodenal stress ulceration. Low-dose antacid treatment without and with additional ranitidine.

Low-dose antacid treatment without and with additional ranitidine in the prevention of acute gastroduodenal stress ulceration in high-risk patients was compared in a randomized, double-blind clinical trial with endoscopic examination of the upper gastrointestinal tract before entry and after the 7-day study period. Of 67 patients who entered the study, 56 could be evaluated. Only one patient, allocated to antacid and placebo, had massive acute upper gastrointestinal bleeding, arising from a gastric ulcer. Although gastric intraluminal pH was better controlled with additional ranitidine treatment, the occurrence of mucosal lesions did not depend on the assigned treatment. We conclude that there is no significant difference between the two regimens in terms of endoscopically visible lesions and clinical outcome.

Acute Disease

Abnormal humoral immune response to Staphylococcus aureus in patients with Staphylococcus aureus hyper IgE syndrome.

Patients with the S. aureus hyper IgE syndrome (SAHIGES) have an abnormal IgE response to cell wall and surface antigens of S. aureus. In this paper we describe the detection of IgE antibodies to soluble antigens of staphylococci (S. aureus and S. epidermidis) and qualitative abnormalities of the IgG response to soluble S. aureus antigens in patients with SAHIGES. These findings may be of pathogenetic importance and help to delineate SAHIGES from other diseases.

Adult

[X-Ray findings of the complications of central venous catheters (author's transl)].

The increasing use of central venous catheters requires knowledge of possible hazards. Complications such as pneumothorax, hemothorax, hematomas in the chest wall or mediastinum and pulmonary emboli caused by the catheter are easily seen on plain chest films. Cardiac tamponade, perforation of vessels, air emboli and thrombosis have to be considered as a possible cause in case of sudden deterioration of a patient.

Adult