Biomedical subjects

F Rooney

Publications and source records attributed to F Rooney.

7 recordsLinked to original sources

PubMed2001

Structure revision and assignment of absolute stereochemistry of a marine C21 bisfuranoterpene.

The C21 bisfuranoterpene (-)-isotetradehydrofurospongin-1 (6), previously isolated from a Western Australian Spongia sp., has been reisolated from a specimen of Spirastrella papilosa collected during scientific trawling operations in the Great Australian Bight. A 2D NMR analysis of 6 has prompted reassignment of the published structure 5, while degradation and chiral HPLC analysis have allowed determination of the absolute stereochemistry.

Animals↗

PubMed2001

Mirabilin G: a new alkaloid from a southern Australian marine sponge, Clathria species.

A Clathria sp. collected during scientific trawling operations in the Great Australian Bight, Australia, has yielded the new alkaloid mirabilin G (1). A structure was secured for 1 by detailed spectroscopic analysis and comparison to known marine alkaloids.

Alkaloids↗

PubMed2000

1,9-Dimethylhypoxanthine from a southern Australian marine sponge spongosorites species.

A Spongosorites sp. collected off southern Australia has yielded 1, 9-dimethylhypoxanthine (4). The structure for 4 was solved by spectroscopic analysis.

Animals↗

PubMed2000

Clathrins A-C: metabolites from a Southern Australian marine sponge, clathria species.

A Clathria sp. collected in the Great Australian Bight has yielded the novel metabolites clathrins A (6), B (7), and C (8). Structures were assigned to clathrins A-C on the basis of spectroscopic analysis. Clathrin A (6) represents a plausible biosynthetic intermediate that provides an inferred link between marine sesquiterpene/benzenoids and mixed terpene/shikimate biosynthesis.

Animals↗

PubMed1998

Callyspongynes A and B: new polyacetylenic lipids from a southern Australian marine sponge, Callyspongia sp.

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Acetylene↗

PubMed1998

Dragmacidins: new protein phosphatase inhibitors from a southern australian deep-water marine sponge, spongosorites sp

A Spongosorites sp. collected during trawling operations off the southern coast of Australia returned the new alkaloid dragmacidin E (3), the structure of which was secured by detailed spectroscopic analysis. Dragmacidin E (3), and its co-metabolite dragmacidin D (1) have been identified as potent inhibitors of serine-threonine protein phosphatases.

Journal Article↗

PubMed1992

Community assessment.

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Community Health Nursing↗