Biomedical subjects

F Roggero

Publications and source records attributed to F Roggero.

7 recordsLinked to original sources

PubMed1999

Stage-modified international prognostic index effectively predicts clinical outcome of localized primary gastric diffuse large B-cell lymphoma. International Extranodal Lymphoma Study Group (IELSG)

BACKGROUND: The definition of prognostic parameters in early stages of gastric lymphoma is still controversial. The aim of this retrospective analysis was to assess the value of the stage-modified international prognostic index (IPI) in predicting the outcome of a large, consecutive series of patients with PGL of diffuse large B-cell histology (DLCL). PATIENTS AND METHODS: Three hundred twelve consecutive, newly-diagnosed, patients with localized PGL (stages I-IIE according to the 'Lugano staging system for GI lymphomas') referred from April 1972 to December 1997 to eight Italian and one Swiss centers were reviewed and their outcomes updated to June 1998. One hundred three patients were treated with single-modality therapy, while two hundred four received combined-modality treatment, most of which included surgery and short-term chemotherapy. RESULTS: After a median follow-up of 66 months (range 0.6-300 months), 195 (64%) were alive in first continuous complete remission (CCR). The five-year estimates of overall survival (OS) and event-free survival (EFS) were 75% and 67%, respectively. OS and EFS varied according to IPI, from, respectively, 90% and 82% for patients with 0-1 risk factors, to 40% and 35% for patients with > or = 3 risk factors (P = 0.00001). Cox regression analysis showed that IPI was the strongest predictor of survival. CONCLUSIONS: This study shows that stage-modified IPI is an effective predictive model in patients with primary DLCL of the stomach, enabling identification of patients with significantly different outcomes.

Adolescent↗

PubMed1994

[Morgagni-Larrey diaphragmatic hernia. Personal case series].

The diaphragmatic hernia described by Morgagni in 1761 and by Larrey in 1829 is a rare diaphragmatic anomaly that may be considered nearly always congenital. It is called in so many ways, but the authors think that "anterior diaphragmatic hernia of Morgagni-Larrey" is the most correct name. Usually asymptomatic in the first years of life, it may be discovered by chance or cause problems in the adult or elderly patient. The Morgagni-Larrey hernia includes every peritoneal or visceral hernia across an anterior diaphragmatic door limited by the right xifosternal-costal wall and, on the back, by diaphragm, pleura and pericardium. Morgagni-Larrey hernia usually has a peritoneal sac, that distinguishes this hernia from the Bochdalek one. Because of the presence of the sac, Morgagni-Larrey hernia probably begins in the fetal phase of diaphragmatic evolution, when pleura and peritoneum separate and the diaphragm becomes a real muscle. The hernia often contains: transverse colon, liver, epiploon, but sometimes there may also be small bowel, stomach, pancreas, gallbladder. The diagnosis of Morgagni-Larrey hernia is usually radiological; a thoracic radiography can demonstrate the presence of diaphragmatic hernia especially when the viscera contained in the sac contain air. So you can see different images in a second radiography one hour later to the first, depending on variation of contained air.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

PubMed1981