[Comparison between local treatment with vitamin A acid cream (Tretinoin Roche) and systemic treatment with oxytetracycline in acne vulgaris. A controlled clinical study].
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Biomedical subjects
Publications and source records attributed to F Reymann.
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One hundred ninety-six patients with multiple basal cell carcinoma were studied to clarify the relationship between multiple basal cell carcinoma and internal malignant neoplasms. No substantial deviations between the expected number and the observed number of cases of internal malignant neoplasms were found. On examination of patients who had histories of arsenic intake, a markedly high number of internal tumors were found in women but not in men. The figures are too low to prove that arsenic treatment can cause an increase in the incidence of internal malignant neoplasm, but they do indicate that more comprehensive studies are needed.
The results obtained over a period of more than five years are reported for 171 patients with more than 1,000 basal cell carcinomas treated solely with curettage. This method of treatment gives fine cosmetic results, and the rate of recurrence is very low. Certain aspects in this series make it impossible to state the rate of recurrence as a definite figure. Some patients had innumerable tumors, and others exhibited diffuse skin lesions resulting in pseudorecurrences. The establishment of a special service for patients with multiple basal cell carcinomas has contributed to the low number of recurrences.
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