Search PubMed⌕ Search

Biomedical subjects

F Röpke

Publications and source records attributed to F Röpke.

At least 19 recordsLinked to original sources
PubMed1998

[Determination of prostate-specific antigen (PSA) in cytosol of breast tumors and human endometrium--new diagnostic approaches].

Prostate specific antigen is a highly specific marker of prostatic tissue. Recent studies have shown, that it is present in several other human tissues, tumors and fluids. PSA has been identified as a serine protease and member of the kallikrein family of enzymes. In our study PSA concentration was measured in 97 cytosols of breast cancer tissues and 14 samples, prepared from human endometrium. Cytosols were analysed also for steroid hormone receptors, EGF-receptor, Cathepsin D and pS-2 protein. PSA was found in 84.5% of breast cancer tissues and in 12 endometrium samples. High concentration of PSA were associated with high pS-2 protein levels. No correlation was found between the concentration of steroid hormone receptors and PSA in our material. The results suggest, that PSA in cytosol of human breast cancer and endometrial tissues may be an additional new prognostic indicator.

Biomarkers, Tumor↗
PubMed1994

[HELLP syndrome on the 6th puerperal day. Presentation of case reports].

We show by two case reports, that the HELLP-syndrome is the most severe form of pre-eclampsia and associated with a relative high maternal and perinatal mortality because of the sudden onset of the complications. In the first case report we describe the development of this syndrome after two eclamptical convulsions on the 6th day of puerperal period. A similar case has not been published yet in all literature. In the second report a mother died by rupture of the capsule of liver because of the HELLP-syndrome 72 hours after Section caesarea. We want to show, that caesarean section cannot avoid this complication. It is not in all cases the most advantageous procedure of delivery in patients with HELLP-syndrome.

Adult↗
PubMed1983

[Changes in the automatically analyzed features of fetal heart rate patterns and fetal movements as influenced by atropine sulfate].

The influence of atropine sulphate (0.01 mg/kg body weight of pregnant women i.v.) on several parameters of fetal heart rate was investigated with automatic analysis of FHR. Fetal movements were counted, too. After administration of atropine, there was a first period with an "inverse" effect of atropine in all fetuses: decrease in baseline FHR (5.1%, minimum after 4.5 min) and increase in the amplitude of FHR fluctuation (44.6%). Thereafter, in a second period the "true" atropine effect appeared: increase in baseline FHR (15.5% above the level before atropine maximum after 25.1 min) and decrease in the amplitude of fluctuation (64.5%). In the third period baseline FHR returned to normal values but the amplitude of FHR fluctuation as well as the beat-to-beat irregularity remained small in 12 from 14 fetuses. Fetal movements registered by the mothers decreased significantly in this time. The results demonstrate a dualistic effect of atropine in the fetus. Moreover, the amplitude of FHR fluctuation (amplitude of macrofluctuation) and the beat-to-beat irregularity (microfluctuation) changed in an equal manner and appear to be influenced by similar regulatory processes. The divergence in the reaction of the baseline FHR and the amplitude of fluctuation together with a decrease in fetal movements might be caused by a central nervous effect with a change in the behaviour of the fetus.

Atropine↗
PubMed1979

[Use of types W 401 external tocometer and BMT 504 foetal monitor for external tocography and recording of foetal movements (author's transl)].

Described in this paper is an external tocometer, Type W 401, for complementary use to Type BMT 504 foetal monitor (VEB Messgerätewerk Zwönitz, GDR). Its applications can be expanded by combination with additional measuring and recording instruments of the BMT series. This will widen possibilities for differentiated external tocography and systematic monitoring of foetal movements. Recording examples are given.

Female↗
PubMed1978

[A method for automatically analysis of antenatal cardio-tocograms (author's transl)].

An off-line computer analysis of antenatal cardiotocograms has been developed. The fetal heart period (interbeat interval), the signals from uterine contractions and fetal movements, the maternal heart period and the continuous time are recorded on magnetic tape. A marking of single steps and of special events during this investigation is possible. For data processing the sequence of measuring values must be divided in shorter intervals (as a rule with a length of 30 seconds).--After this the mean value of FHR and of MHR is calculated for each interval. By computation of the standard deviation (S), the index of instantaneous arrhythmia (IAI), and the number of macrofluctuations of these intervals a quantification of the heart rate short-time-variability and long-time-variability can be performed.

Diagnosis, Computer-Assisted↗
PubMed1978

[Dynamics of the dilatation of as uteri during birth].

219 partogramms of primipares and 219 partogramms of multipares were analysed retrospectively. Only normal deliveries after normal pregnancies were taken into consideration. Graphs were plotted of time intervalls against the width of the cervix. The mean duration of dilation were 6 hours for multipares and 9 hours for primipares. All phases of first stage of labour were reduced in multipares. The results were compared with observations of other authors.

Cervix Uteri↗
PubMed1978

[Heart rate during perinatal period].

Observations on heart frequency during the perinatal period. Registrations of the fetal heart rate were carried out on 133 children before and after delivery. 3 different types of heart rate patterns were found, each of them could be subdivided in 2 groups. The several groups are different in the shape and the steepness of fetal heart rate ascent after delivery. Supplementary other fetal parameters were examined (Apgar-score, time of the first breath, moment of first newborn cry, onset of regular respiration). These parameters showed significant associations with the above-mentioned types of the fetal heart rate patterns. For the blood gas parameters however such relations to the heart rate patterns were not found.

Apgar Score↗
PubMed1977

[Intravenous induction of labor with prostaglandins F2alpha].

Report on 60 patients with induction of labour by intravenous infusion of prostaglandin F2alpha. The high rate of success (95%) was attributed to some favourable factors. Side effects were minimal. Moreover no effects on the metabolism were observed. During labour a electronical and biochemical supervision is neccessary.

Blood Glucose↗
PubMed1976

[Clinical problems in extreme fetal retardation].

Three cases of extreme fetal somatic retardation are reported. Fetal retardation is the consequence of chronic placental insufficiency and is affected with a high lethality. It is necessary to recognize suspicious cases by anamnesis and clinical findings; a method of differential diagnostic procedure is described. After demonstrating the placental insufficiency and sufficient fetal maturity the indication for finishing pregnancy is given even though the fetus is extremely small.

Adult↗
PubMed1976

[Electronic urethro-cystometry before and after reconstructive surgery using the Zoedler method].

Electronical measurement of pressure in the bladder and urethra of 9 incontinent women treated by the Zoedler-plastic. A comparison of pre- and postoperative levels yielded the following results: 1. The functional length and the closing-pressure of the urethra show uncharacteristic changes of the levels only. The expected postoperative rise of the levels have not come true. 2. The vesico-urethral quotient at strain (pV max/pU max) is (with the exception of one case) corresponding to the result of the operation. 3. The clinical recovery from incontinence after the Zoedler-plastic is combined with small changes in the pressure-graphs only.

Adult↗
PubMed1975

[Urometry using a biomonitor combination].

Description of an apparatus for electronical measurement of pressure at the efferent urinary passages of the woman is given. The combination may be fitted in a variable way from elements of the biomonitor series of the VEB Kombinat Messgerätewerk Zwönitz. Pressure values can be recorded simultaneously by means of three separate measuring canals. The apparatus is suitable for clinical and scientific examinations such as cystometry, simultaneous cystourethrometry and uretermanometry. Additionally typical pressure graphs are demonstrated.

Female↗
PubMed1975

[Functional studies on the implanted ureter].

Electronical measurements of pressure in 8 successfully implanted ureters (6 Boari-Plastics, 2 direct implantations) yielded the following results. 1. Frequency, amplitude, duration and rate of spreading of the contractions show no differences compared to the normal ureter. 2. In the Boari-plastic the peristaltic activity is transferred also to the area of the anastomosis between bladder-flap and ureter. 3. Increasing pressure of bladder by retrograde filling produced temporary impairments of peristaltic of the implanted ureter in one case only.

Adult↗