Search PubMed⌕ Search

Biomedical subjects

F R Hendrickson

Publications and source records attributed to F R Hendrickson.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

Treatment of carcinoma of the hypopharynx.

In a review of 80 patients with hypopharyngeal squamous-cell carcinoma, 43 patients were found to have had lesions arising in the pyriform sinus, 34 had lesions arising on the postcollateral wall of the hypopharynx, and 3 had lesions in the postcricoid area. Therapeutic modalities included radical radiation therapy in 56 patients, radiation plus surgery in 13 patients, and planned combined therapy in 11 patients. The five-year determinate survival rate of all the patients was 20%. Patients with posterolateral wall tumors had a 23% rate of cure, but those with pyriform sinus tumors had only a 13% rate of cure. The five-year determinant survival rate was 12.5% for patients undergoing radical radiation therapy, 15.4% for those undergoing unplanned radiation and surgery (salvage therapy), and 55.6% for those with planned combined therapy. Over 40% of the patients had a recurrence of their disease; an additional 20% developed distant metastatic spread which usually occurred within the first year. The type of therapy did not alter the rate of recurrence but did affect the rate of distant metastatic spread, with planned combined therapy greatly improving control of the primary lesion. This study suggests that, even with advanced disease, the most effective therapy for hypopharyngeal carcinoma is planned combined radiation therapy and surgery.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Accuracy in patient setup and its consequence in dosimetry.

Analysis of 5575 settings on a computer-monitered Theratron-80 60Co unit demonstrates that human error does occur in treating patients with radiation. The errors are due to inaccurate setting of such parameters as field size, gantry angle, collimator rotation, treatment time, etc. The error rate per parameter was found to be about 3%, and more than two-thirds of the patients monitored with the PDP 11/45 computer had at least one error at some stage during the full course of treatment. Both the dose and the dose distribution may be affected by these errors and have been studied in a few typical cases. The errors in timer setting have the largest effect on the prescribed dose and may change the probability of local control appreciably.

Cobalt Radioisotopes↗