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Biomedical subjects

F Peyre

Publications and source records attributed to F Peyre.

30 records · Page 2Linked to original sources
PubMedDate not supplied

[Neuropsychiatric aspects of HIV infection and AIDS].

Neurotropism of H.I.V. has recently been recognized. More than one third of Aids patients have neurological complications (infections, tumors, multifocal progressive leuko-encephalopathy...) attributed to immunological failure. Necropsy reveals more frequent neuropathology (75%). "AIDS Dementia Complex" (A.D.C.) has been described. Neuropsychological impairment (and personality alteration) is frequent (20-40%) even in asymptomatic patients. H.I.V. infects the C.N.S. early in the course of viral infection and prior to the development of classical associated neurological abnormalities. Mental disorders are frequent: anxiety, depression, suicidal behavior, etc. They can be psychological reactions, although they are often already present before H.I.V. infection in "high risk groups". The signification of psychosis is discussed. Overview of literature.

AIDS Dementia Complex↗
PubMedDate not supplied

[Potentiation of antidepressive treatment by thyroid hormone therapy. Review of the literature].

The association of thyroid hormone and antidepressant has been proposed for about twenty years, mainly for refractory depression treatment. Review of ten trials made since 1969 does not bring positive arguments in favor of this association (most of these trials have poor or no methodology). It is necessary to undertake double-blind placebo controlled studies on refractory depressed inpatients, in order to ascertain the real usefulness of this association.

Antidepressive Agents↗
PubMedDate not supplied

[Predictive factors in the bipolarization of depressive disorders].

Since 1966 maniac-depressive illness has been divided into bipolar disorder (BP) and unipolar disorder (UP). Both groups are still in the process of subtyping (bipolar I,II,III and the tentative subtyping of unipolar group by Winokur). When affective disorder begins with depressive episodes is it possible to predict future mania and anticipate BP diagnosis? Are they variables of good predicting value for bipolarization? The issue is of importance since handicap, evolution, prognosis, treatment are somewhat different for UP and BP. Several studies indicate some possible predictors of bipolarization: pharmacological mania, bipolar familial antecedents, postpartum first episode, hypersomnia and psychomotor retardation, psychotic depression, etc. Special attention is given to switch to mania during antidepressant treatment.

Adult↗