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Biomedical subjects

F Pavani

Publications and source records attributed to F Pavani.

18 recordsLinked to original sources

Reappraising the apparent costs of attending to two separate visual objects.

Support for object-based accounts of visual attention has been drawn from several different types of effect. One effect is found when observers try to restrict their attention to a particular region of a display. Other regions belonging to the same object are often selected as well, suggesting that attention spreads spatially over entire objects. Another effect is found when judging two visual attributes; performance is often less efficient when the attributes belong to separate objects rather than both belonging to a single object. This latter effect has been taken to imply that only one segmented object can be attended at a time. However, it may instead merely be a variant of the first effect. If, as we assume here, attention spreads to task-irrelevant regions of relevant objects, it will encompass a larger spatial region and more information when judging attributes of two objects rather than one. Here we compared judging one versus two objects, while manipulating whether the two objects occupied a wider extent than the single object condition (as in previous work), or not. Costs were found for judging two objects versus one only when together they occupied a wider spatial extent. We conclude that reported difficulties in attending two objects may be due to attention spreading across the entire spatial extent of objects when judging their parts, rather than a fixed inability to process more than object at a time.

Adult↗

Crossmodal links between vision and touch in covert endogenous spatial attention.

The authors report a series of 6 experiments investigating crossmodal links between vision and touch in covert endogenous spatial attention. When participants were informed that visual and tactile targets were more likely on 1 side than the other, speeded discrimination responses (continuous vs. pulsed, Experiments 1 and 2; or up vs. down, Experiment 3) for targets in both modalities were significantly faster on the expected side, even though target modality was entirely unpredictable. When participants expected a target on a particular side in just one modality, corresponding shifts of covert attention also took place in the other modality, as evidenced by faster elevation judgments on that side (Experiment 4). Larger attentional effects were found when directing visual and tactile attention to the same position rather than to different positions (Experiment 5). A final study with crossed hands revealed that these visuotactile links in spatial attention apply to common positions in external space.

Adult↗

Are perception and action affected differently by the Titchener circles illusion?

In the present study, we investigated the effects of the Titchener circles illusion in perception and action. In this illusion, two identical discs can be perceived as being different in size when one is surrounded by an annulus of smaller circles and the other is surrounded by an annulus of larger circles. This classic size-contrast illusion, known as Ebbinghaus or Titchener Circles Illusion, has a strong perceptual effect. By contrast, it has recently been demonstrated that when subjects are required to pick up one of the discs, their grip aperture during reaching is largely appropriate to the size of the target. This result has been considered as evidence of a clear dissociation between visual perception and visuomotor behaviour in the intact human brain. In this study, we suggest and investigate an alternative explanation for these results. We argue that, in a previous study, while perception was subjected to the simultaneous influence of the large and small circles displays, in the grasping task only the annulus of circles surrounding the target object was influential. We tested this hypothesis by requiring 18 subjects to perceptually estimate and grasp a disc centred in a single annulus of Titchener circles. The results showed that both the perceptual estimation and the hand shaping while grasping the disc were similarly influenced by the illusion. Moreover, the stronger the perceptual illusion, the greater the effect on the grip scaling. We discuss the results as evidence of an interaction between the functional pathways for perception and action in the intact human brain.

Adult↗

Neuropsychological evidence of the functional integration of visual, auditory and proprioceptive spatial maps.

We infer the functional integration of the visual, auditory and proprioceptive spatial maps from the behaviour of a patient (G.A.) with left visual neglect, i.e. a derangement of visual space representation. G.A. was required to point manually to left, centre or right acoustic stimuli, under visual control or blindfolded, with the responding hand (left or right) located either on the left, centre or right space. G.A.'s manual pointing responses to left auditory stimuli were strongly influenced by the visual spatial information and by the proprioceptive spatial information related to the position of the responding effector. In the visual control condition, when the patient performed the task with the left effector located on the left, pointing responses to left auditory stimuli were shifted towards the right intact visual space. In contrast, when the visual spatial information was rendered less salient, i.e. in the blindfolded condition, and the effector was again located on the left, manual pointing responses were confined to the previously ignored left space. These findings are consistent with the view that the acoustic representation is modulated by the impaired visual representation and by the proprioceptive spatial map related to the position of the responding effector.

Acoustic Stimulation↗

Moving around objects and recognizing them.

This research concerned the use of mental rotation in recognizing rotated objects. Instead of the classic Shepard's paradigm in which subjects were still while observing rotated objects, here subjects had to move (or imagine moving) around stationary three-dimensional objects put in the middle of the trajectory. Thus, depending on the viewing positions, such objects were seen under six different perspectives (from 30 degrees to 180 degrees). The latter task has been thought to be closer to everyday life in which we obtain information regarding objects from their spatial properties. The results do not follow the classic rules of mental rotation of an object predicting a linear increase of the time needed to recognize distorted objects as a function of their angular displacement. They also differ from data in the literature about spatial imagery showing that access to spatial information is facilitated more when people actually move through a path than when they imagine moving. A probable explanation of this difference from the literature is discussed in relation to the particular involvement of the body in the experimental task.

Adult↗

[Diagnostic use of the mathematical model of nonlinear regression in the interpretation of the crystalline bilirubin loading test in Gilbert's syndrome].

The results of a study conducted both on subjects affected by constitutional hyperbilirubinaemia (Gilbert's syndrome) and healthy subjects using the charge test with crystalline bilirubin are presented. The parameters which are involved in bilirubin kinetics were established by means of non linear regression methods (the Marquardt method). 19 Gilbert syndrome patients and 12 normal control subjects were studied. Important parameters readily applicable to clinical and diagnostic evaluation of subjects suffering from familial cholemia were identified.

Bilirubin↗

[Abdominal ultrasonography in the staging and follow-up of malignant lymphomas].

During the period September 1980-June 1984, abdominal US was performed by the authors on 103 patients with confirmed malignant lymphomas. The results indicate US has accuracy comparable to that of lymphography for lymph node enlargement; furthermore, US has the added advantages of being able to demonstrate mesenteric, renal hilar and other abdominal lymph nodes that are not commonly filled with contrast medium during lymphography. For these reasons, US is now frequently used in the diagnosis and staging of malignant lymphomas as well as for following up the results of therapy.(US = ultrasonography)

Abdomen↗

[Comparative diagnostic value of echography and oral radiologic examination of the gallbladder in relation to surgical findings].

For nearly 60 years, since it was introduced by Graham and Cole (1924), oral cholecystography (OCG) has been used as the imaging technique of choice in investigation of gallbladder disorders. Recently, the future of OCG has come into doubt, principally as a result of ultrasonography, with the advent of high-resolution real-time scanning. Stones are seen as echoes within the lumen of the gallbladder and are associated with an acoustic shadow, findings which are highly specific. On this basis, to evaluate the accuracy of ultrasonography in detecting cholelithiasis, the A. have performed by real-time cholecystosonography 60 patients with not diagnostic OCG in a group of 546 patients affected by gallbladder diseases. Our results have confirmed that sonography revealed 4 normal gallbladders, 51 gallstones and 1 primary gallbladder cancer, with 5 cases of false positive. The true false negative rate has been difficult to determine, as surgery is usually not performed after a negative study. The accuracy of cholecystosonography for gallstone diagnosis was found to be 88,1% for all three Crade's categories.

Cholecystography↗

[Value and limits of echography and abdominal lymphography in malignant lymphomas].

Diagnostic results obtained by echography and lymphography in the study of abdominal lymphoglandular involvement in patients with lymphomas are compared. The data indicate that while lymphography is more revealing, the two examinations should be used together in staging. Echography, on the other hand, should be used for long-term surveillance, once the lymphographic contrast medium has been absorbed.

Female↗

[Study of intestinal transit using a radioisotope method].

Intestinal transit patterns were studied in 20 normal volunteers. It was found that small changes in transit time occurred in the passage from the caecum to the sigmoid and rectum, and that most subjects evacuated the capsule 38 hr after its ingestion.

Capsules↗

[Changes in intestinal transit time induced by bromopride in functional diseases of the colon].

Intestinal transit time was studied in two groups of 8 patients with irritable colon. In the first group, the time was longer than normal, whereas in the second it was accelerated. Three subjects in each group received a placebo, while the other five received 60 mg/day bromopride for 15 days. No change in transit time was noted in the controls. Two subjects in Group I displayed a significant reduction in transit time after bromopride, while deceleration and normalisation were observed in 4/5 patients in Group II.

Adult↗