[Parenteral nutrition before surgery: selection of candidate patients for a preoperative parenteral nutrition plan].
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Biomedical subjects
Publications and source records attributed to F Pardo.
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OBJECTIVE: To evaluate the safety and usefulness of systems for obtaining central venous access. DESIGN: Prospective open study. SETTING: Clinica Universitaria de Navarra, Spain. SUBJECTS: 218 consecutive patients who required long term venous access either for chemotherapy or for total parenteral nutrition, and who had no evidence of infection, a platelet count of over 40 x 10(9)/l, and a life expectancy of three months or more, had 234 devices inserted. INTERVENTIONS: Insertion of either a silicone rubber (Port-A-Cath) or a polyurethane (Implantofix) catheter into the cephalic, jugular or subclavian vein, leaving the tip in the superior vena cava. RESULTS: Between February 1985 and December 1990, 234 devices were implanted in 218 patients aged from 0.9 to 78 years. The median (range) length of time that the catheters functioned was 277 (7-1887) days. The overall incidence of complications was 0.09/100 days inserted, and the complication rates for infection and thrombosis were 0.02 and 0.03/100 days, respectively. Thirty two devices were removed because of complications, and 19 because the treatment had finished. Five of the 218 patients (2%) were lost to follow up. CONCLUSIONS: These devices have a long working life, and a low rate of complications, and are of great value to patients who require long term or cyclical intravenous treatment.
En bloc transplantation of the liver, duodenum and pancreas has been successful in humans for the treatment of tumors requiring exenteration of the upper abdomen. We have developed an experimental model in 40 pigs of en bloc transplantation of the liver, duodenum and pancreas. The surgical technique for organ harvesting and preservation has been correct as the early graft function was excellent. We describe in detail the surgical technique in the recipient animal, the anesthetic model and the autopsy findings. Liver function was excellent and endocrine pancreatic function was normal within 8 hours after transplantation. Absorption and insulin-secreting response was normal in a few animals studied with an oral glucose overdose and with the intravenous glucagon test.
Pyomyositis is an infection of the striated muscle seen frequently in Africa but rarely in Western countries with a temperate climate. Over the last few years it has been observed with increasing frequency, especially in immunocompromised hosts. An unusual case of pyomyositis in a 65-year-old immunocompetent woman is described. The disease emerged during septicemia caused by Staphylococcus aureus. It was associated with pleuropneumonia and affected two different and opposite groups of muscles. Diabetes mellitus, a known predisposing factor, was diagnosed during the infection. The diagnosis of pyomyositis was based on microbiological cultures, computed tomography, and radio-labelled granulocyte scintigraphy. Follow-up until recovery was based on computed tomography. Surgical drainage of abscesses was avoided thanks to early diagnosis and specific antibiotic therapy.