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Biomedical subjects

F P Stuart

Publications and source records attributed to F P Stuart.

At least 127 records · Page 7Linked to original sources
PubMed1968

Rejection of renal allografts: specific immunologic suppression.

Kidneys were transplanted across a major genetic barrier (Ag-B locus), from LewisxBN F(1) hybrid rats into bilaterally nephrectomized Lewis rats. Survival of grafts is prolonged (indefinite?) in rats treated with a combination of (i) intravenous injection of donor spleen cells 1 day before the graft, and (ii) passive immunization with antiserum prepared in rats of the recipient strain against donor spleen and lymph-node cells. The recipient's immune response to other antigens is not impaired.

Animals↗
PubMed1968

Transplantation.

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Animals↗
PubMedDate not supplied

Stress conditioning: a novel approach to organ preservation.

Effective stress conditioning can extend the safe cold storage time of rat kidneys to 48 hours. We demonstrated that planned induction of the stress response, by heat shock, can be used to stress condition the transplant organ and protect it against the damages of cold storage. A powerful and useful protective mechanism exists in a latent form in all cells. This mechanism can be rapidly activated in a controlled and planned way to allow tissues temporarily to resist injury. Through stress conditioning it is possible to provide a high level of protection in situations in which stress can be anticipated and planned for.

Animals↗