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Biomedical subjects

F Oberklaid

Publications and source records attributed to F Oberklaid.

88 records · Page 5Linked to original sources

Hyperactivity. Symptom complex or complex symptom?

The phenomenon of "hyperactivity" is well recognized. Results of long-term follow-up studies show that children diagnosed as "hyperactive" are at risk for severe problems during adolescence and adulthood. However, no common diagnostic criteria exist for "hyperactivity." The term can refer to a number of very different behaviors, and children diagnosed as "hyperactive" may also exhibit one or more concomitant difficulties. A "hyperactive" child should be carefully assessed to determine the nature of the behavioral problem and its source, and the term "hyperactivity" itself should be used with caution.

Attention↗

The Pediatric Examination of Educational Readiness: validation of an extended observation procedure.

The Pediatric Examination of Educational Readiness (PEER) is a standardized observation system for use by health care professionals. It combines a prekindergarten physical examination with a neurodevelopmental and behavioral assessment. The PEER was field tested on 386 children, of whom 22% revealed a "definite concern" in one area of development or behavior, 8% in two, and 14% in three or more areas. (A concern was a finding that required direct intervention, continuing surveillance or further evaluation.) Children with multiple areas of concern were found to have lower teacher rating scores at the end of kindergarten than those with isolated or no concerns. An observation procedure, such as the PEER, can be a productive part of the pediatric assessment of children entering kindergarten.

Child↗

Why colic?

Explore the source record for details and available documents.

Adult↗

Developmental-behavioral dysfunction in preschool children. Descriptive analysis of a pediatric consultative model.

A study of 79 preschool children referred to an interdisciplinary clinic because of behavioral problems and developmental concerns was done. Historical data and information regarding present functioning were collected using standard questionnaires. In addition to medical, neurological, and psychiatric examinations, every child received a neurodevelopmental assessment. When compared with a matched cohort of children from the community, the clinic population had a higher incidence of developmental concerns. Of 37 children referred because of "hyperactivity" or other behavioral concerns, 13 had previously undetected developmental concerns requiring specific interventions. Dysfunction in preschool children may be the result of an ongoing reciprocal interaction between constitutional predispositions and social and environmental factors. A comprehensive, developmentally oriented approach seems to be indicated in the assessment of these children. This may have implications for pediatric practice.

Affective Symptoms↗

Achondroplasia and hypochondroplasia. Comments on frequency, mutation rate, and radiological features in skull and spine.

An attempt was made to ascertain all the dwarfs in the State of Victoria. The incidence of achondroplasia proved to be approximately 1 in 26,000 live births in the period 1969 to 1975 when ascertainment was nearly complete. This indicates a mutation rate of 1.93 X 10(-5) per generation in this locus. Paternal age was shown to influence mutation. Ascertainment in earlier years of the study was low despite the very great effort made to find all cases. Patients with hypochondroplasia were particularly difficult to find. However, 25 cases were found for study. Overlap between hypochondroplasia and achondroplasia was found in all features except the facial appearance (which was the basis of definition). Achondroplasia was more severe in all regards, but some individuals with hypochondroplasia were very short and some had extreme degrees of spinal canal stenosis. The classical measurements used to describe the skull changes in acondroplasia failed to distinguish this condition from hypochondroplasia. More efficient indices were devised, but visual assessment of the size of the facial region compared to that of the cranial valult proved more reliable than any index. The clinical distinction based upon facial appearance remains the arbitrary basis of definition.

Achondroplasia↗

Asphyxiating thoracic dysplasia. Clinical, radiological, and pathological information on 10 patients.

Review of 10 cases of asphyxiating thoracic dysplasia has shown a wide range of clinical effects and some variability in the radiographic features. Respiratory difficulty was severe in 7 babies and lethal in 6 of these. The seventh child is remarkable for his normal stature and excellent health at 15 years of age. 3 babies had no respiratory difficulty but 2 of them subsequently died of renal failure; one remains alive at 3 years. Microscopical abnormalities in the liver and kidneys were very frequent and appeared to increase progressively with age.

Adolescent↗

'Juvenile' myasthenia gravis in early infancy.

A previously well infant developed severe muscle weakness and hypotonia at 6 months of age. This was reversed by anticholinesterase medication. However, she had subsequent further weakness and died at 10 months after an acute respiratory arrest. The clinical pattern was that of the 'juvenile' form of myasthenia gravis rather than the 'congenital' forms which have previously been described in early infancy.

Age Factors↗

The Opitz trigonocephaly syndrome. A case report.

This is the third report, to our knowledge, of a baby with Opitz trigonocephaly syndrome of multiple congenital abnormalities. The unusual facial and palatal abnormalities are diagnostic.

Abnormalities, Multiple↗

Parents, infants and health care: utilization of health services in the first 12 months of life.

OBJECTIVE: To describe patterns of health-service use in the first 12 months of life. METHODS: In this prospective cohort study, 173 first-born infants and their families living in two middle socio-economic urban areas of Melbourne were enrolled consecutively when presenting for their initial maternal and child health nurse (MCHN) visit (at approximately 4 weeks of age). Families kept a daily "health diary" for the entire 12-month period, recording use of all health services for their infant, and reasons for the contact. RESULTS: There was an 87% completion rate of diaries. The mean number of visits to any health service, including medical, hospitals, MCHN services, pharmacists, allied health services and naturopaths, was 35.7 (95% CI 34.7-36.6) during the 12 months. Of these, 31% (mean 10.9 visits) were visits to a general practitioner (GP) and 41.5% (mean 14.3 visits) were visits to the MCHN. Infants' visits to the MCHN were far more frequent in the first 6 months of life compared with the second 6 months (10.3 vs 3.6, P < 0.001). Rates of GP use were constant over the same periods (5.3 vs 5.7, P = 0.8). CONCLUSIONS: In a universal health-care system, this high rate of health-service use equates to approximately one visit to a health service every 2 weeks in the first year of life. The majority of these visits appeared unrelated to illness. This previously undocumented data has implications for future integrated service delivery, health-professional training and policy development for this age group.

Adult↗