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Biomedical subjects

F Nicolas

Publications and source records attributed to F Nicolas.

At least 109 records · Page 6Linked to original sources
PubMed1976

[Problems posed by anesthesia in the hypertensive treated with beta-blockaders].

The use of beta-blocking agents against hypertension and their rapid extension in daily practice we have to consider the problem of anesthesia of a patient undergoing such treatment. Continuation of the treatment increases the operative risk, discontinuation long before the operation leaves the hypertension to reappear and discontinuation 48 hours before may lead to a coronary or arrhythmic accident. Therefore, except in case of emergency, treatment may be maintained until the day before the operation, and in case or emergency extensive atropinisation is desirable. Finally prescription of selective beta-blocking agents decreases the risks.

Adrenergic beta-Antagonists↗
PubMed1975

A study of the electroencephalogram during surgery with deep hypothermia and circulatory arrest in infants.

Seveteen infants (2 1/2 to 28 months old) were continuously monitored by six-channel electroencephalography (EEG) during the entire surgical procedure of open-heart repair. They were subjected to surface hypothermia supplemented by cold extracorporeal circulation (ECC) down to an average esophageal temperature of 21 degrees C., to cardiac arrest of 40 minutes average (range 19 to 62 minutes), and to ECC rewarming. Survival time of the EEG was correlated to esophageal temperature at the time of arrest. EEG reappeared an average of 26 minutes (5.30 to 50) after the strat of rewarming ECC and became strictly continuous after 44 minutes. Reappearance latency was well correlated with the duration of arrest. Potential normalization was oberved in 13 infants, but true normalization was observed in only 2 infants during the 90 to 120 minute period after ECC. By judging the EEG and by comparing this series with two previous series of moderate and deeper hypothermia in older patients, we concluded that the immediate tolerance of the brain to deep hypothermia and circulatory arrest seems no different in infants and in older patients.

Body Temperature↗