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Biomedical subjects

F Nicolas

Publications and source records attributed to F Nicolas.

170 records · Page 10Linked to original sources

[A prognostic study of 238 cases of chest trauma. Influence of the delay in admission in an intensive care unit (author's transl)].

238 cases of chest trauma were studied according to the same protocol. With this protocol we can perform on the one hand a comprehensive study of the prognosis according to the thoracic lesions and associated lesions and on the other hand a prognostic study according to the delay of admission in a intensive care unit. All our data show that the most serious lesion is the pulmonary contusion and that mortality increases if an associated lesion is present, according to its nature. On the other hand a comparison was performed between the patients directly admitted in the intensive care unit (GI) and the patients hospitalized after a delay (GII) this comparison shows that in G II patients the rate of complications was higher, the mortality more important and respiratory sequelae more frequent than for patients of GI with thoracic lesions of the same importance or less important. These data show that an early admission of chest trauma patients in an intensive care unit is desirable and that the duration of this hospitalization must be at least 3 or 6 days.

Adult↗

[Acute respiratory distress syndrome (ARDS) in cerebral malaria (author's transl)].

Non hemodynamic pulmonary edemas included by some authors in the acute respiratory distress syndrome (ARDS) had been reported in cerebral malaria. We describe a new case. Clinical data, hemodynamic studies with PWP measurement, and anatomic findings are coherent with the diagnosis of ARDS. Although the underlying causal mechanisms--the marked parasitemia and its consequence on permeability of the pulmonary capillary--remain speculative, they seem credible. The pulmonary lesions are provoked by these main factors and worsened by hypoprotidemia and surinfection. Prevention of all these factors can stop the evolution towards refractory hypoxemia but the precocity of quinine treatment remains the most important point.

Acute Disease↗