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Biomedical subjects

F Nakajima

Publications and source records attributed to F Nakajima.

At least 91 records · Page 5Linked to original sources
PubMed1991

[Posterior fossa hemorrhage 11 years after the use of silastic dural substitute: case report].

A case of posterior fossa hemorrhage is reported. The hemorrhage occurred 11 years after posterior fossa craniotomy with closure using a graft of silastic dural substitute. This 14 year-old girl underwent suboccipital craniotomy at the age of 3 years because of traumatic posterior fossa hemorrhage. The dura mater was repaired with a piece of dural substitute. Eleven years later, she developed severe headache and vomiting. Computerized tomography scanning revealed a high density area in the right posterior fossa. At exploration, a fresh clot was evacuated between the dural graft and the fibrous scar tissue. The resected fibrous scar tissue was 1cm thick, and was adhering to the duro glial scar tissue. Her postoperative course was uneventful, and she was discharged 2 weeks after surgery. Microscopic examination of the fibrous scar tissue revealed an outer layer of loose connective tissue with numerous capillaries. The inner layer consisted of dense connective tissue. It was speculated that fragile capillaries of fibrous scar tissue caused this hemorrhage. Surgeons should not forget this complication although silastic dural substitute is less used than it used to be.

Adolescent↗
PubMed1990

[Simultaneous occurrence of renal cell and transitional cell carcinoma in the same kidney and ureter. A case report].

An unusual case of 2 concurrent primary renal tumors within the same kidney is reported. A 70-year-old woman presented with gross hematuria when she was in the hospital for cerebral infarction. Excretory urography revealed a marked expansion of the right kidney with no renal function. CT scan showed a mass arising from the right kidney, the hydronephrotic right renal pelvis, and a mass in the lower right ureter. Selective renal angiogram showed marked neovascularity of the mass. There was an encasement of the intrarenal artery to the lower pole. Angiographic findings were highly suggestive of a renal cell carcinoma with a second neoplasm in the renal pelvis. Subsequently, the patient underwent right radical nephroureterectomy and partial cystectomy. Section of the removed specimen revealed a 4.0 X 3.8 cm solid tumor confined to the kidney in the upper pole and a transitional cell carcinoma arising from the renal pelvis. In addition, transitional cell carcinoma was present in the distal ureter.

Aged↗
PubMed1990

[Absorption of tetrahydropyranyl adriamycin administered intravesically immediately after transurethral resection of bladder carcinoma].

Absorption of tetrahydropyranyl adriamycin (THP) administered immediately after transurethral resection of bladder carcinoma (TUR-Bt) has not been reported. In this study, we have examined the absorption of THP and the systemic toxicity in the early post-TUR period. Of 21 patients with bladder carcinoma, 10 had a solitary tumor and 11 multiple tumors. Twenty mg THP in 40 ml of sterile water was intravesically administered on days 1, 3, 5, 7, 14 and 28, and then every 4th week. The THP solution was retained for 2 hours. The blood THP concentration was measured 30 minutes and 2 hours after the intravesical administration on days 1, 7 and 28. No systemic side effects were observed. Thirteen of the 38 (34%) samples contained a detectable level (more than 1 ng/ml) of THP on the post-TUR-Bt on day 1, 8, of 42 (19%) on day 7, and 3 of 18 (17%) on day 28. Altogether, 24 of the 98 (24%) samples contained more than 1 ng/ml THP. The highest blood THP level was 23 ng/ml on day 1. The differences between frequency of detection of blood THP in the samples at 30 minutes and 2 hours were not statistically significant. The difference between average concentration of blood THP of patients with solitary and multiple tumors also was not significant. These results indicate that intravesical THP administration starting within 24 hours after TUR-Bt can not result in significant systemic absorption of THP, and the systemic toxicity can be avoided.

Absorption↗
PubMed1990

[Atresia hymenalis with acute urinary retention: a case report].

We report a case of atresia hymenalis in a 14-year-old girl presenting with a clinical symptom of acute urinary retention. On physical examination she was found to have a lower abdominal mass and an imperforate bulging hymen. She underwent hymenal incision, and subsequently the symptom disappeared. It is very uncommon for atresia hymenalis to manifest itself with acute urinary retention as the first clinical sign, but we should consider this disease if a pubertal girl seeks medical opinion for acute urinary retention.

Acute Disease↗
PubMed1989

Structure of the so-called 'prismless' enamel in human deciduous teeth.

The surface enamel of human deciduous teeth showing a more negative birefringence by polarized light was investigated by differential interference contrast microscopy and by scanning electron microscopy (SEM) following EDTA etching. Though this surface enamel has been generally called the 'prismless' enamel, in this study, the so-called 'prismless' enamel was categorized into 'false', 'moderate', 'essential' and 'complex' types according to whether they took the form of distinct prisms which bended at the subsurface, indistinct circularly based prisms or not. Based on the SEM observations some types of the 'prismless' enamel showed parallel crystallites and no prism boundaries. However, if indistinct prisms showing centripetal crystallites within the circular boundaries are admitted into the prismless enamel, other types except the 'false' one will generally belong to it.

Birefringence↗
PubMed1989

Distribution patterns of the surface "prismless" enamel in human deciduous incisors.

Distribution patterns of the "prismless" enamel were investigated in the labial, lingual, and proximal surfaces of human deciduous incisors under transmitted light through a differential interference contrast. The "prismless" enamel was generally either a short-length (0.2-0.3 mm) type, including island-like and isolated step-like shapes, or a long, band-like type, including relatively short (0.5-1 mm) and longer (2-5 mm) shapes. The island-like type was commonly observed at various intervals in the surfaces; the isolated step-like type was relatively rare. The longer band-like type was found in the maxillary labial and maxillary and mandibular proximal surfaces, but, in the other surfaces, this type was not seen. The surface enamel possessing the longer band-like type was also higher in the ratio of the total length of the "prismless" enamel to the whole surface length than the other surfaces. The frequency of the "prismless" enamel tended to be higher in the cervical region and lower towards the incisal edge.

Child↗
PubMed1988

Acute spontaneous subdural hematoma of arterial origin.

Acute spontaneous subdural hematoma of arterial origin is very rare. We have encountered two such cases and verified the arterial origin of the bleeding at operation. Both patients had no history of head trauma and developed progressive neurological deficits, becoming comatose. The source of bleeding was identified as a cortical artery located on the temporal lobe near the Sylvian region. This type of lesion is reviewed in the literature and the etiology is discussed.

Acute Disease↗
PubMed1988

Infantile chronic subdural hematoma with local protrusion of the skull in a case of osteogenesis imperfecta.

Osteogenesis imperfecta with infantile chronic subdural hematoma is extremely rare and has not been previously described in the literature. Our patient was a baby girl suffering from osteogenesis imperfecta tarda (Type I) who had an acute subdural hematoma at birth and who developed a progressive chronic subdural hematoma with local protrusion of the overlying skull. She was treated surgically with a good result. This rare complication is due to weakness of an insufficiently calcified skull, which is peculiar to this disorder of bone and connective tissue development.

Chronic Disease↗
PubMed1987

Subdural empyema occurring 20 years after trauma: case report.

The authors report a case of subdural empyema that occurred 20 years after a severe closed head injury and was treated surgically with good results. Traumatic subdural empyema of this late onset is rare. The literature is reviewed, and the mechanism of a delayed presentation is discussed.

Brain Injuries↗
PubMed1987

[Endoscopic ethanol injection treatment for bladder cancer].

One invasive and 4 superficial bladder cancers were treated by local injection of absolute ethanol through an endoscope. With the patient placed in the lithotomy position, an endoscope was introduced after mucosal anesthesia with xylocaine jelly. According to the usual manner of retrograde catheterization, a 23G syringe needle attached to a 5F ureteral catheter was advanced into the base of the tumor and through the needle absolute ethanol was injected. This treatment is characterized by endoscopic delivery of ethanol as with sclerotherapy for esophageal varices to obtain a potent necrotizing effect as achieved by transcatheter embolization of ethanol for the treatment of renal cell carcinoma. As a rule, this technique does not require any anesthesia other than mucosal anesthesia with xylocaine jelly and can be done repeatedly and very easily, thus having a high cost effectiveness. This treatment serves as a good palliative therapy for invasive bladder cancers, because of its rapid achievement of hemostasis and reduction of the tumor masses. Furthermore, this treatment is just as effective as standard transurethral resections to eradicate superficial bladder cancer, even though the treatment may have to be repeated.

Administration, Intravesical↗
PubMed1987

[A case of adrenal ganglioneuroma].

A 40-year-old female was admitted to the department of internal medicine of our hospital for evaluation of left sided diaphragm elevation, cardiomegaly and splenomegaly. CT scan incidentally revealed a 5 X 5 cm solid mass in the right adrenal and the patient was referred to our department of urology. Endocrinological studies and angiography indicated a non-functioning right adrenal tumor without any remarkable signs of malignancy. Right adrenalectomy was performed. The tumor was smooth-surfaced, measured 6 X 5 X 5 cm and weighted 50 g. The cut surface was yellow-white and demonstrated interlacing bundles of fibers. Histopathological examinations revealed a typical structure of ganglioneuroma. Ganglioneuroma is a very rare tumor most of which arise in the posterior mediastinum. To the best of our knowledge, this is the 17th case of adrenal ganglioneuroma in the Japanese literature.

Adrenal Gland Neoplasms↗
PubMed1987

[A case of bilateral synchronous renal cell carcinoma managed with radical nephrectomy and ex-vivo tumor enucleation].

A 61-year-old female presented with gross hematuria and left flank pain. The arteriogram and CT scan revealed a large left renal tumor and multiple small right renal metastatic tumors. A chest X-ray and Ga scintigram showed no other metastatic lesions. A left radical nephrectomy and a right renal bench surgery were performed at the same time. The right multiple tumors were enucleated and the right kidney was autotransplanted into the right iliac fossa. The postoperative course was uneventful and the patient was free of tumor with good renal function. Renal preservation surgery was considered more beneficial for this patient than bilateral nephrectomy followed by hemodialysis.

Carcinoma, Renal Cell↗