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Biomedical subjects

F Nager

Publications and source records attributed to F Nager.

At least 73 records · Page 4Linked to original sources
PubMed1975

[Proceedings: Pacemaker implantation bradycardia and cardiac insufficiency. Preliminary report].

The longterm effects of pacemaker therapy have been investigated in 337 patients with bradycardia and congestive heart failure with or without Adams-Stokes syncope. The cumulative survival rate in patients with Adams-Stokes seizures without congestive heart failure (group I) is markedly better than in patients with Adams-Stokes seizures and congestive heart failure (group II). The death rate is highest in patients with congestive heart failure as sole indication for pacemaker implantation (Group III). In the patients from group II (mainly with slight to moderate decompensation) there was a higher percentage of improvement than in those from group III (chiefly with severe congestive heart failure), in whom cardiac decompensation improved in approximately half the cases. These findings do not prompt excessive enthusiasm about the longterm results in patients with bradycardia and severe congestive heart failure. The indication subsists where there is resistance to drug therapy, or digitalis intolerance, or where treatment with a provisional pacemaker produces good results.

Adams-Stokes Syndrome↗
PubMed1975

[Epidemiology and clinical aspects of infectious endocarditis].

There has been a change in the epidemiological, etiological and clinical pattern of infective endocarditis. This changing pattern has been substantiated by comparison of 156 cases of infective endocarditis seen over the period 1947-1957 (period I) and 227 cases treated during the period 1961-1974 (period II). Epidemiologically the pathomorphosis consists in a slight decline in "medical" cases, contrasted with a marked increase of--predominantly acute--cases after cardiac surgery. Etiologically the change is characterized mainly by a reduction of streptococci (61%/33%) and a much higher incidence of virulent organisms, especially staphylococci (3%/21%), as the infective agent. With regard to the clinical picture of infective endocarditis, the changing pattern is apparent in an increase in atypical and misleading features and an often oligosymptomatic presentation. In period II the classical signs were more often absent. The difference in the course of infective endocarditis consists in a higher hospital mortality during period II. In this period the main cause of death was refractory heart failure, often provoked by acute rupture of the aortic valve. The factors which may be responsible for this change and the clinical implications are discussed. The difficulties in early diagnosis and the role of misleading symptoms of this still "malignant" disease are outlined. Special interest is focused on the diagnostic problems involved in recognizing acute endocarditis, right-heart endocarditis and acute rupture of the aortic valve.

Adult↗
PubMed1975

[Pacemaker implantation for heart failure with bradycardia (author's transl)].

The long-term effect of pacemakers in the management of bradycardic heart failure with or without syncope was tested on 337 patients. The cumulative survival rate of patients with Adams-Stokes attacks without heart failure (group I) was 91% at the end of one year, 73% at the end of three and 35% at the end of eight years. Among patients with Adams-Stokes attacks and accompanying heart failure (group II) 81% survived one year, 64% three and 46% five years, but only 25% eight years. Among patients in whom heart failure was the only indication for pacemaker implantation (group III), 70% were still alive after one year, 56% after three and 17% after five years. Related to the severity of heart failure before and after pacemaker implantation, most of the patients of group II (mild or moderately severe failure) had definite improvement, while of those in group III (mainly severe failure) only about half had less cardiac failure. In patients with severe heart failure and bradycardia (without syncope) long-term results are not likely to be very good, as regards both duration of survival and physical capacity.

Adams-Stokes Syndrome↗