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Biomedical subjects

F Nödl

Publications and source records attributed to F Nödl.

11 recordsLinked to original sources
PubMed1979

[Spindle-shaped cell blue naevus with lymph nodes "metastases" (author's transl)].

"Metastases" in lymph nodes are not only found from cellular blue naevi but also from their spindle-shaped cell fascicular type. These "metastases" are mostly situated in the fibrous capsule, very rarely in the parenchyma of the lymph nodes. Individually the cells resembled those of the cutaneous tumour. Their occurence in the peripheral sinuses should be verified. Epitheloid vessel-wall cells (glomus-type cells), sometimes pigmented and occasionally found in large cell aggregates, can be noted in the capsule of the lymph nodes. By several authors, these cells are considered to be benign naevus cells. The histopathogenesis and the clinical importance of the "metastases" from blue naevus are discussed.

Aged↗
PubMed1979

[Elastofibroma cutis].

A 9 year old boy sought medical attention because of a cutaneous infiltrate of the nape that could not be diagnosed macroscopically. Microscopic examination showed it to be a fascicular fibroma of a special structure. The striking feature of the stroma was the distinct proliferation and degeneration of the elastic fibers. The alteraions of the elastic tissue are similar to those seen in elastofibroma dorsi. It is discussed if the lesion results from a hyperplasia of true elastic or/and pseudo-elastic fibers.

Child↗
PubMed1978

[The special relations of malignant skin lymphomas to the epidermis and to the epidermal appendages (author's transl)].

Epitheliotropia of malignant skin lymphomas is an unexplained phenomenon which equally affects epidermis and ectodermal appendages. This phenomenon is found especially in tumours of probable T-cell origin. However it can also be observed in B-cell lymphomas (immunocytomas) and is therefore not an exact criterium for the biological origin of a lymphoma. In the case of germinal center tumors we could not find evidence of epitheliotropia. An active invasion of neoplastic cellular infiltrate into the epithelium must be differentiated from the phenomenons caused by passive pressure, resulting from the expansion of the tumor. However, one has to remember that epitheliotropic malignant lymphomas invade the epidermis in all stages of development. It is shown, that Pautrier microabscesses are only a special non specific aspect of epidermotropia.

B-Lymphocytes↗
PubMed1978

[Endothelioma of the skin].

We are reporting on a 71 years old woman suffering from a plaque-like raised nodular neoplasia that existed for two years. The histological changes, though local variable, are characterized by similar structures. The tumor cells are grouped in variably shaped, loose syncytial cords, just by loosing their cytoplasma in vascular-like cavities. Because of their morphological relations to mesenchym Bolck called these tissue-formations "spongiosynchymal" structures. They are considered by this author to characterize the common tissue-attribute of all endotheliomas and similar neoplasias. Additionally the histological pattern of these tumors can show, as in the present case, solid and epitheloid cell formations.

Age Factors↗
PubMed1977

[Loss of hair].

Explore the source record for details and available documents.

Alopecia↗
PubMed1977

[Anastomoses and epitheloid vessel-wall cells of lymph nodes close to the skin (author's transl)].

A report is given on age-related changes found in special morphological areas of the hilus vessels. These vessels, together with the physiological involution of lymph node parenchyma, are of importance for the deposition of melanoma cells. The hyperplasia of epitheloid cells of the vessel walls in the lymph node capsule as well as their possible misidentification as micro-metastases of melanoma cells is discussed.

Aged↗
PubMed1976

[On the effectiveness of lymph-nodes as filter cells in metastasizing melanoma (author's transl)].

Even without previous ray-treatment the mechanical effectivenes of the filtration ability of lymph-nodes may be reinforced by connective tissue growth around metastatic melanoma cells. On the other hand melanoma cells can pass this filter just because of the possibility to get into the lymph stream by means of wide lymphatics even within the first series of regional lymphatic ganglia. This is true also for passing the marginal lymphatic sinus and subsequent entering the vas efferens of the lymph-node. The therapeutical inferences of these observations are discussed.

Humans↗
PubMed1976

[Hemangioperocytoma in the infant. A histogenetic study].

Two children with hemangiopericytomas are reported-one with a congenital tumor, the second hemangiopericytoma was noticed during the first trimenon. Histologically there was no obvious difference to the hemangiopericytomas in adults. Tumor immaturity should not be seen as a nondifferentiation but as an embryonal immaturity. In analogy to other reticulo-histiocytic proliferations, reticular fibers, shown by silver impregnation, can be demonstrated in both cases. The silver stain should not be over-rated in its diagnostic and prognostic significance.

Facial Neoplasms↗