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Biomedical subjects

F N Bamford

Publications and source records attributed to F N Bamford.

15 recordsLinked to original sources

Sleep in the first year of life.

The sleep patterns of 174 infants were recorded on one typical day at six, 13, 26 and 52 weeks of age, using a 24-hour log. During the first year of life the number of episodes of sleep was reduced by about 50 per cent, but total sleep time was reduced by only two hours. A circadian rhythm was established by six weeks of age. Smaller infants slept more than larger ones in the first months of life. Sex or birth-order of the child did not affect the duration or number of sleep episodes, but sleep pattern related significantly to whether or not mothers found their infants difficult to feed. Introduction of weaning food at an early stage reduced the number of sleep episodes, but increased the average length of each episode. Socio-economic status showed no significant relationship with number of episodes or total length of sleep.

Circadian Rhythm

Sex difference in fetal head growth.

Growth of the fetal biparietal diameter (BPD) throughout the second and third trimesters was measured in a prospective longitudinal study. Linear-cubic equations were fitted to the data of individual fetuses and from these equations mean growth curves were produced for males and females. The head growth trajectories of males and females were significantly different. The study illustrates why the practice of dating pregnancies by ultrasonic fetal BPD measurement at about 16 weeks gestation can lead to error.

Cephalometry

An adolescent ward.

A ward has been set up for adolescents, who, being neither children nor adults, have special needs. It provides a pleasant and enthusiastic atmosphere that allows the patients to mix together socially alties is important, but not more than 20% should be long-stay patients. Those needing intensive care or specialised investigations and those likely to be a disruptive influence are excluded. No serious sexual problems have been encountered.

Adolescent

Growth hormone deficiency in children with brain tumors.

Nine children with brain tumors are described who have received various combinations of treatment, including surgery, radiotherapy, and chemotherapy. Many of the children were noted to be of short stature. Endocrine assessment was carried out from 2 to 10 years after treatment. The combined results of insulin tolerance and Bovril stimulation tests show an impaired growth hormone response in six of the nine children. Bone age is retarded in all cases, and the present height is below the 10th percentile in five of the six. The cause of this growth hormone deficiency is obscure, but further studies are in progress.

Adolescent

Residual disabilities in children treated for intracranial space-occupying lesions.

A retrospective study of 30 long-term survivors of cranial or craniospinal irradiation for intracranial space-occupying lesions has demonstrated physical and mental handicaps in the majority. This is most severe in those cases treated before the age of 11 years, and is not confined to those children having craniospinal or whole-brain irradiation. The mental handicap also appears to be progressive, but cannot be easily examined in this retrospective study.

Adolescent

Child health and paediatrics in the U.S.S.R.

Observations on child health and paediatrics made during a three weeks' visit to the USSR are recorded. There are separate health services for children and their organization is outlined, as are the training and career structure of the many thousands of paediatricians employed. Provision for handicapped children is briefly discussed and a few comments are made on social aspects of child care.

Adolescent

The community paediatrician in an integrated child health service.

A concept of Community Paediatrics has been described comprising clinical care to individual children including identification, diagnosis, and care of the handicapped child, expertise in preventive paediatric techniques, and the provision of investigation and advice in connexion with social and educational proboems. Its relationship to Community Medicine, General Practice, and Consulting Paediatrics has been discussed and a long-term training scheme is outlined. In the immediate future the deployment is envisaged of senior clinical Medical Officers now employed by Local Authorities.

Child

Pertussis agglutinins in vaccinated children: better response with adjuvant.

Children were immunized with a single batch of pertussis vaccine, either adsorbed on aluminium hydroxide or plain. With a primary course of three injections, adsorbed vaccine produced higher titres of pertussis agglutinins in the serum than did plain vaccine. There was no obvious difference in response between those who received the three doses at intervals of 1-2 months, starting at 3-4 months of age, and those in whom the third dose was delayed until about 6 months after the second, but the number of children in each group was small.

Adjuvants, Pharmaceutic