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F Moya

Publications and source records attributed to F Moya.

At least 55 records · Page 3Linked to original sources
PubMed1985

Ultrasound assessment of the postmature pregnancy.

The use of ultrasound to identify the fetus at risk for postmaturity among postterm pregnancies was evaluated. The ultrasound findings in 85 postterm pregnancies were reviewed. No grade 0 or grade 1 placentas were observed and grade 2 and 3 placentas were found with similar frequency. The incidence of advanced postmaturity was 12.9%. Advanced postmaturity was found with grade 2 and 3 placentas. Oligohydramnios was very common (81.8%) among pregnancies resulting in postmaturity. The neonatal ponderal index was higher with grade 2 placentas than with grade 3 placentas. The presence of immature placentas (grade 0 or 1) is rare after 42 weeks of gestation. Placental grading cannot be used to predict postmaturity.

Adolescent↗
PubMed1981

Treatment of osteoarthritis of the spine and herpetic neuralgia at the Pain Center, Mount Sinai Medical Center.

This presentation will briefly describe the operation of this Pain Center and discuss the two chronic pain problems most commonly seen in our geriatric population: osteoarthritis of the spine and herpetic neuralgia. Osteoarthritis of the spine is the most common radiologic finding in middle-aged and older people with low back pain. 32% of our patients have this diagnosis as the basis of their chronic pain. The typical patient is 72 years old and has a past pain history which includes several years of back pain treated by various physicians with anti-inflammatory agents and analgesics to no avail. Past history of surgery and drug abuse is rare; however, depression is common. Therapy at the Pain Center is primarily the use of an exercise program and epidural and/or subarachnoid steroids. At the last visit, approximately 70% of the patients have had significant improvement. Herpetic neuralgia is found in 13% of all patients seen at the Mount Sinai Medical Center Pain Center. Our typical patient is 73 years old and has had PHN for 10 months unrelieved by various topical and oral medications. Although rarely is there a history of drug abuse or surgery, extreme depression is common. If the duration of the neuralgia is less than one year, 85% of patients get significant or complete relief from the use of sympathetic nerve blocks and/or the subcutaneous infiltration of steroids and local anesthetic. Once the PHN has been present for more than one year, only 55% of the patients are improved.

Florida↗
PubMed1980

Dissociation of cell density and cell cycle effects on the rate of transport of alpha-aminoisobutyric acid in 3T3 cells.

The rate of transport of alpha-aminoisobutyric acid (AIB) has been measured in Swiss 3T3 cells at different cell densities in the range 10(3) to 5 x 10(4) cells/cm2. There is a pronounced increase in the rate of Na+-dependent AIB uptake below 4 x 10(3) cells/cm2, which can be observed both in growing cells (10% serum) or in cells arrested early in the G1 (G0) portion of the cell cycle in medium containing plasma-derived serum. The rate of AIB transport of cells arrested in G0 can be inhibited by the addition of a plasma membrane-enriched fraction prepared from 3T3 cells. The results are interpreted in terms of two elements that control the rate of AIB transport, one dependent on the position in the cell cycle and the other on cell contact. Preliminary observations suggest that BALB 3T3 cells behave in a similar way.

Aminoisobutyric Acids↗
PubMed1980

Schwann cells proliferate but fail to differentiate in defined medium.

Primary cultures of dorsal root ganglia cells from 18- to 21-day rodent embryos were studied for their ability to express Schwann cell function in a defined medium lacking serum and embryo extract. It was confirmed that Schwann cells, but not fibroblasts, are able to proliferate in response to contact with axons when cultured in this defined medium. We here report that in this medium, however, differentiation of Schwann cells was arrested before completion of ensheathment and before initiation of myelin formation. Electron microscopic analysis confirmed this ensheathment failure and showed that the extracellular matrix components (basal lamina and thin collagenous fibrils) normally produced by axon-related Schwann cells had not been formed. This absence of extracellular matrix, as well as the presence in the Schwann cell of an increased cytoplasmic granularity (observed in the light microscope) and numerous distended cisterns of rough endoplasmic reticulum, suggest a failure in Schwann cell secretion. However, within one week after addition of serum and embryo extract to the culture medium, the ensheathment failure was corrected and myelination occurred; electron microscopic observations showed the presence of basal lamina and collagen fibrils in association with Schwann cells. These results suggest the presence in serum or embryo extract (or both) of factors necessary for the full expression of Schwann cell function (although a similar requirement is not present for the expression of oligodendrocyte function in culture). We propose that these observations indicate a linkage between Schwann cell secretion and axonal ensheathment, including myelin formation.

Animals↗
PubMed1979

The relation of temperature and lipid composition to cell adhesion.

We have examined as a function of temperature the effect of changes in the composition of the fatty acid chains of membrane phospholipids on the rate of cell to cell adhesion in the neuronal cell line B103. The rate of cell to cell adhesion in this cell line is highly temperature dependent but is not influenced by changes in the fatty acid composition of the plasma membrane generated by growing the cells either in the presence of oleic acid or elaidic acid. In contrast the temperature dependence of the rate of cell to cell adhesion, measured in a monolayer adhesion assay, is highly dependent on the shear force used during the assay. A two-step model of cell to cell adhesion involving multiple adhesion ligands is presented which can be used to explain these observations.

Cell Adhesion↗
PubMed1978

Low back pain.

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Back Pain↗
PubMed1975

Calcitonin biosynthesis: evidence for a precursor.

Calcitonin biosynthesis has been studied in chicken ultimobranchial glands incubated in vitro in the presence of radioactive amino acids. The results obtained suggest the existence of a biosynthetic precursor of higher molecular weight or procalcitonin. This precursor has been identified by pulse-chase experiments, molecular weight determinations, biological activity measurements and analysis of tryptic peptides. Its molecular weight is about 13000 (calcitonin, about 3500) as determined by polyacrylamide gel electrophoresis. Procalcitonin is present in small amounts in chicken ultimobranchial glands and it is biologically active in rats.

Animals↗