Search PubMed⌕ Search

Biomedical subjects

F Morin

Publications and source records attributed to F Morin.

68 records · Page 4Linked to original sources
PubMed1972

A comparative study of the molecular structures of the plasma membranes and the smooth and the rough endoplasmic-reticulum membranes from rat liver.

Plasma-membrane as well as smooth-, rough- and degranulated-endoplasmic-reticulum-membrane fractions were isolated from the microsomal pellet of rat liver. The purity of these fractions, as determined by marker-enzyme activities, electron microscopy, cholesterol content and RNA content, was found to be adequate for a comparative structural study. Major differences in lipid and protein composition were found to exist between the plasma membrane and the endoplasmic reticulum, but not between the smooth and the rough fractions of the endoplasmic reticulum. Differences in the location of membrane protein thiol groups and the mobility of the membrane phospholipids were observed between the plasma membranes and the endoplasmic reticulum, and these could be explained by differences in protein and lipid composition. However, by employing fluorescence and spin-labelling techniques structural changes were also observed between the smooth and the rough endoplasmic-reticulum fractions. These results suggest that the structural heterogeneity existing between the two latter membrane fractions occurs near or on their membrane surfaces and is not due to the greater number of ribosomes bound to the rough endoplasmic-reticulum fraction.

Animals↗
PubMedDate not supplied

Subtalar arthrodesis in children.

We present a clinical and radiological retrospective study of 30 patients (51 feet) with valgus deformity of the feet who had three different types of subtalar extraarticular and intraarticular arthrodesis. Children with cerebral palsy, myelomeningocele, and agenesis of the corpus callosum associated with progressive polyneuropathy were studied. The results were considered excellent and satisfactory in 73% of the feet. The combined Grice-Green-Batchelor procedure gave the best results, with 84% excellent and satisfactory results, with bony union in 96% of the feet. Weight-bearing films of the ankles in the anteroposterior plane are essential to determine the true extent of the deformity before operation.

Agenesis of Corpus Callosum↗
PubMedDate not supplied

[Comparison of the diagnostic performance of students of the old and new medical curriculum at the Laval University].

In the Fall of 1982, the "Université Laval" School of Medicine inaugurated a new undergraduate curriculum consisting primarily in the introduction of problem-based learning to foster the development of clinical reasoning. The purpose of the study was to compare the diagnostic performance of the students of the old (n = 118) and the new (n = 120) program. The measurement instrument consisted of 12 short clinical vignettes. There is no significant difference in the performance of the students from the two programs. In spite of these results, it is advocated to wait before initiating yet another curriculum reform or reversal. Finally and for both classes of students, their performance varied significantly from hospital to hospital. A number of suggestions are made to better standardize the quality of clinical teaching across the different hospital settings.

Canada↗