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Biomedical subjects

F Mazas

Publications and source records attributed to F Mazas.

At least 37 records · Page 2Linked to original sources

[Nontraumatic aseptic osteonecrosis of the femoral head. Etiopathogenic, developmental and therapeutic considerations: review of the literature].

Aseptic non-traumatic necrosis of the femoral head occurs in patients with very unusual general state of health. Despite the fact that the metabolic abnormalities are better known today, many problems with regard to prognosis and treatment remain. According to the author's experience and, review of the literature, the authors consider that the production of tissue repair with hypervascularity is an aggravating factor. Disturbance of lipoproteins plays a major aetiological role. Decompressive forage should be reserved for the early stages. Secondary degenerative arthritis is almost constant after conservative surgery in cases that have been assessed. The authors obtained good results after Luck's adjusted cups and they consider that this is a reliable procedure. They have observed a high level of septic complications after total prosthesis. It is thought that this is related to the general condition of the patient.

Arthroplasty↗

[Total radiocarpal prosthesis. Preliminary study].

The mechanical requirements before satisfactory muscular balance in a total wrist prosthesis have been studied in 25 cadavers. The centre of rotation was determined in X-Rays; it was localised in the sagittal plane crossing the axis of the forearm and in the frontal plane situated in front of the axis of the forearm. A graphic model of the wrist was then established. A total prosthesis was then designed, made up of two components with a torus surface. This prosthesis was found to be compatible with the wrist model. Movement required forces only slightly greater than normal muscular activity. One male was operated on using this prosthesis. The result was satisfactory after one year.

Adult↗

[Isolated traumatic dislocation of the extensor carpi ulnaris tendon].

The authors describe one case of post-traumatic dislocation of the extensor carpi ulnaris tendon. They found eleven other cases reported in the literature. The type of lesion should be looked for in cases of trauma to the wrist without a bony lesion. The treatment should be surgical when function is impaired, either shortly after the initial trauma or if the dislocation becomes habitual. The aim is to reconstruct a tendon sheath. The results were generally satisfactory.

Adult↗

[Recent fractures of the scapula. Apropos of 43 cases].

The authors have studied a series of 43 fractures of the scapula. They confirm the results are generally good. However, 12 displaced fractures of the neck of the scapula have been seen. All were treated conservatively with only one good result, the other results being fair or poor. These results are explained by the fact that displaced fractures of the neck disorganize the coraco-acromial arch. This type of fracture should be surgically treated as an articular fracture by open reduction and plate fixation. Fractures of the glenoid should also be treated surgically.

Adolescent↗

[Carpal tunnel syndrome due to mycobacterium bovis BCG (author's transl)].

A 45-year-old woman, previously in good health developed chronic tenosynovitis with carpal tunnel syndrome a few weeks after wounding herself with a Pasteur pipette containing BCG cultures. She had received two injections of triamcinolone in the anterior annular ligament of the right carpa. The patient recovered after twelve months of antituberculous therapy associating isoniazid (300 mg/day), ethambutol (800 g/day), and rifampicine (400 mg/day). This is the first report of BCG tenosynovitis of the hand. The hazards of steroid injections into the tendon sheaths are pointed out.

Antitubercular Agents↗

A radiological study of the wrist centers of rotation.

To ensure the total replacement of wrist, it seems necessary to determine the main kinematic specifications of mobility and stability of this joint. After a review of the literature, the authors have determined, by the classical X-rays graphic method, the positions of both radial-ulnar deviation and flexion-extension centers, on 26 alive normal wrists. The data, in some ways different from Youm's, introduce to the conditions of stability of any wrist in a functional situation. The center locus (on the forearm axis in a front view, quite anterior in a lateral view) is, in some ways, an answer to the question of muscular equilibrium during prehensile efforts, so to the amount of strains the joint must bear, and consequently to the design of a total wrist prosthesis.

Adult↗

[Total shoulder replacement by an unconstrained prosthesis. Report of 38 cases (author's transl)].

The authors have operated on 38 patients using an original type of unconstrained prosthesis with fixation to the acromion. One prosthesis had to be removed for sepsis, 5 have dislocated and 32 are stable. Most of the cases were improved as regards pain but 14 shoulders remained very stiff. The indications for surgery are discussed, the state of the rotator cuff being particularly important.

Acromion↗

[70 patients operated on for sciatica without herniated disk].

Seventy patients suffering from sciatica were operated in whom no disc herniation was found. In 42 instances, compression of bony origin was found. These cases were either due to general narrowing of the spinal canal with signs in the distribution of several roots with neurological intermittent claudication, or to narrowing of the lateral recess or intervertebral foramen with involvement of only one root. Decompressive surgery was always beneficial for pain. In 20 instances a disc was found to be only bulging; disc excision was performed in 17 of these patients. In 8 instances, no abnormality was found. Some patients were nevertheless cured by disc excision, a single laminectomy being useful. The incidence of additional psychological problems is discussed. It is concluded that the clinical signs should guide the surgeon rather than the radiological findings in decisions for surgical treatment. Patients who have been correctly treated by conservative means for an adequate time should be systematically operated on if they have not shown sufficient clinical improvement.

Adult↗

[Bone penetration of cefazoline (author's transl)].

A single intramuscular dose of one gram of cefazoline was administered to fifty eight patients undergoing total hip replacement. The elimination of the antibiotic in femoral head is parallel to the blood elimination but ten times lower. Twelve hours after injection, levels of 0.5 microgram/g (i.e. higher than MIC of Staphylococcus aureus normally isolated from post surgery infections) are still detected in capsule and femoral head.

Aged↗

Prophylactic cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomised trial.

The effect of five days of antibiotic prophylaxis with cefazolin injections (beginning just before surgery) on postoperative infections (beginning just before surgery) on postoperative infectious complications was evaluated in a double-blind, randomised, placebo-controlled trial in nine centres on 2137 patients undergoing hip replacement. Antibiotic prophylaxis reduced the number of hip infections significantly from 3.3% (placebo) to 0.9% (cefazolin). Positive peroperative blood samples and positive bacteriological examination of the drain were risk factors for hip infection but the prognostic value of obesity, diabetes, or previous hip surgery was not confirmed. Development of a urinary infection was not related to hip infection. Hip infections were less common in the four centres with hypersterile operating theatres, and the benefits of prophylactic antibiotics were restricted to patients having hip replacement operations in conventional theatres.

Aged↗