The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit.
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Biomedical subjects
Publications and source records attributed to F Maurer.
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The illness-process of four patients, two with MEN I (Wermer syndrome) and two with MEN IIa (Sipple syndrome) is described and the therapeutical proceeding explained. The fundamental principle of therapy is the extirpation of hormone producing tumors, in the course of which MEN requires a special sequence in surgical proceeding. Although curative therapy was not possible in all cases, all four patients are still alive. The period of observance surveyed amounts from one year up to eleven years. The importance of family screening is shown in the fact that in two families more sick people were to be found.
Cowden's disease, also called multiple hamartoma syndrome, is a clinical entity characterized by hamartomatous tumours of endodermal, mesodermal and ectodermal origin. Although extremely rare, the disease must be known to all internists. A case of Cowden's disease in a 36-year old male patient is reported. The authors insist on the high incidence of digestive disorders and the risk of malignant degeneration of mammary and thyroid tumours. They also describe the cutaneous and mucosal lesions characteristic of the disease.
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