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Biomedical subjects

F Masuda

Publications and source records attributed to F Masuda.

At least 91 records · Page 5Linked to original sources
PubMed1985

[Pancreatic cutaneous fistula as a complication of left nephrectomy].

Intimate anatomical relationship of the pancreas to the left kidney may lead to pancreatic cutaneous fistula as a complication of left nephrectomy. We report 2 cases of pancreatic cutaneous fistulas that developed as a result of surgical trauma to the pancreas during left nephrectomy. The diagnosis was confirmed when amylase in the drainage was increased. Fistulas closed spontaneously by adequate drainage in 55 and 33 days postoperatively.

Adult↗
PubMed1985

[The role of lymphadenectomy in the treatment of renal cell carcinoma].

The usefulness of radical nephrectomy combined with lymphadenectomy for improving the prognosis of renal cell carcinoma was evaluated in 146 patients with this disease during the 21-year period from 1963 to 1983. Eighty-six out of the 146 underwent radical nephrectomy alone, while the remaining 60 patients received radical nephrectomy combined with lymphadenectomy. In cases of stage I and stage IV B, lymphadenectomy produced no improvement in the survival rate. On the other hand, of the 58 patients who had stage II and stage III disease, in the 23 who underwent lymphadenectomy, the survival rate improved significantly as compared to the 35 who did not.

Carcinoma, Hepatocellular↗
PubMed1985

[Diagnosis and treatment of renal angiomyolipoma].

We have hitherto reported 6 cases of renal angiomyolipoma. Recently, we encountered two more such cases. Case 1 is a 34-year-old woman with fever as the chief complaint. DIP revealed a tumor mass in the right upper pelvic pole. This mass showed a strong echo level on ECHO and adipose tissue of low density on CT scan. Therefore, the patient was diagnosed as having renal angiomyolipoma. Since liposarcoma was not ruled out by the examination of frozen sections during operation, nephrectomy was performed. Case 2 is a 40-year-old woman. Diagnosed as having bilateral renal angiomyolipoma, she underwent right nephrectomy 14 years ago. Two years ago, she had heavy hematuria, and had embolization of the left renal artery. She has had no bleeding since the embolization. We are of the view that ECHO and CT can are very useful for diagnosis of renal angiomyolipoma, and embolization for heavy hematuria, a complication, should be performed first of all.

Adult↗
PubMed1985

[5-FU concentration in blood and tissue of patients with renal cell carcinoma after administration of UFT].

UFT (3 capsules; 300mg FT) was administered to five of 10 patients with renal cell carcinoma, and concentrations of FT, 5-FU and uracil in the serum and tissues (normal renal tissues, renal tumor tissues and liver) were determined 5.2 hours on average, after administration. The levels were also compared with these in the five patients administered 300 mg of FT. There was no difference in FT concentration between the serum and the tissues in the group administered UFT, but the concentration of 5-FU in tumor tissues was significantly higher (25.6 times) than that in the serum. The level was also higher (3.2 times) than that in normal renal tissues. There was a positive correlation between the concentration of 5-FU in the tissues and the concentration of uracil in the tissues. Although there was no difference in the concentration of FT between serum and tissues in patients administered UFT or FT, the concentration of 5-FU in patients administered UFT was definitely higher than that in patients administered FT; the concentration of 5-FU in the tumor tissues of patients given UFT was 3.9 times higher than in those given FT. Thus, UFT induced a concentration of 5-FU in tumor tissues that was maintained at a high level, suggesting that an excellent antitumor effect on renal cell carcinoma can be expected with UFT.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1985

[Clinical study of UFT in renal cell carcinoma].

A clinical study of UFT, a mixture of FT and uracil in a molar ratio of 1 : 4, was conducted on 12 patients with renal cell carcinoma. UFT was continuously administered at doses of 300, 400 or 600 mg per day. CR was recorded in 2 patients, PR in 2, NC in 7 and PD in 2, respectively. The overall response rate was 33.3%. Concerning side effects, 2 of the 12 patients suffered from anorexia and stomatitis, but no hepatic disorders or bone marrow suppression was observed. We concluded that UFT therapy was effective for renal cell carcinoma.

Administration, Oral↗
PubMed1985

[The role of preoperative embolization in renal cell carcinoma].

In 84 cases of renal cell carcinoma, the effect of embolization was assessed by dividing the patients into two groups: those having undergone (42 cases) or not having undergone (42 cases) embolization. A 16% decrease in tumor volume following embolization using an MMC-micro capsule was noted. In patients without metastasis at nephrectomy, a tendency was observed for the incidence of postoperative metastasis to be lower with more favorable survival for the group with embolization than that without. On the other hand, among cases with metastasis at nephrectomy, there were more patients who survived for a longer period in the embolization group.

Carcinoma, Renal Cell↗
PubMed1985

[Lymphadenectomy for renal cell carcinoma].

The techniques, results and problems of lymphadenectomy were assessed in 56 cases of renal cell carcinoma. As the approach to the retroperitoneum, the thoracoabdominal approach was used in 22 cases and transabdominal approach in 34 cases. Radical nephrectomy was performed, followed by lymphadenectomy. All of the regional lymph nodes were dissected. The mean time required for lymphadenectomy was 1 hour and 40 minutes and the mean volume of blood loss was 350 ml. As intraoperative complications, vascular injury occurred in 3 cases. In 1 of these cases the left second lumbar vein was injured. Therefore, in lymphadenectomy caution should be exercised not to give injury to this blood vessel. The postoperative complication observed included bleeding and chylous ascites in 1 case each. In performing operations one must ligate the lymphatic vessel carefully. The 5-year-survival rate for 6 cases associated with metastasis to lymph node was 33%. From this fact, it was postulated that lymphadenectomy is helpful to improve prognosis of these patients.

Adult↗
PubMed1985

[Fever in renal cell carcinoma].

Fever developed in 65 (37.8%) out of 172 patients with renal cell carcinoma, being the third most frequent symptom following hematuria and renal mass. Patients who developed fever were associated with symptoms such as palpable renal mass, general malaise anorexia, weight loss, acceleration in ESR, liver dysfunctions and an increase in alpha 2-globulin significantly more frequently than those who did not. Histologically also, high graded cases were more common with a significant. Moreover, the prognosis was significantly more poor.

Adult↗
PubMed1984

Sonographic patterns of renal cell carcinoma with emphasis on relation to tumor size.

The sonographic appearance of 37 renal cell carcinomas was reviewed with particular emphasis on the relationship between the echo pattern of tumor and tumor size. Small carcinomas tended to be solid and hypoechoic; seven lesions less than 5 cm in the largest dimension were either hypo- or isoechoic . The echogenicity level of the solid parts within the lesion, whether it was solid or mixed, tended to increase as the tumor grew. It is important to recognize that the sonographic appearance of renal cell carcinomas varies with the size of the tumor.

Adenocarcinoma↗
PubMed1984

Study of the venous phase on renal angiography in cases of renal carcinoma.

The venous phase on renal angiography was studied in 65 cases of renal carcinoma. Opacification of the renal vein stem was observed in 33 cases (51%). The visualisation rate of the renal vein was lower in high stage than in low stage tumours but there was no difference between these groups if patients with tumour thrombus of the renal vein were excluded from the high stage group. Renal arteriovenous fistulas were observed in six cases (9%), in three of which tumour thrombus of the renal vein was also seen. The thrombus was discovered at operation in 14 of the 65 cases and it was in 10 of these that the striated vascular pattern was observed on renal angiography. Collateral veins were observed in 15 cases (23%), only five of which had tumour thrombus of the renal vein.

Adult↗