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Biomedical subjects

F Marconi

Publications and source records attributed to F Marconi.

50 records · Page 3Linked to original sources

Visuospatial working memory in Turner's syndrome.

Turner's syndrome is a genetic disorder, specific to women, in which one of the X chromosomes is partially or completely deleted. This syndrome is associated with physical features such as short stature or failure in primary and secondary sexual development, together with a specific pattern of cognitive functions. It has been suggested that women affected by Turner's syndrome perform poorly in tasks measuring visuospatial abilities and have a verbal IQ significantly higher than performance IQ. Although this result has received strong empirical support, the nature of the visuospatial deficit is still unclear. Recent studies on visuospatial processes have highlighted that the underlying cognitive structure is more complex than previously suggested and several dissociations have been reported (e.g., visual vs spatial, sequential vs simultaneous, or passive vs active processes). In the present study we analyze in detail the characteristics of the visuospatial deficit associated with Turner's syndrome by presenting four young women with a comprehensive battery of tasks designed to tap all aspects of visuospatial working memory. Results confirm that Turner's syndrome is associated with a general visuospatial working memory deficit, but the pattern of performance of different cases can be different, with a greater emphasis on active visuospatial processes. and on either sequential or simultaneous spatial processes.

Adult↗

[Current orientations in the treatment of bone metastases].

Bone metastases are the most frequently occurring tumours of the skeletal system. Clinically, diagnosis is important but more so the treatment, taking into account the type of lesion, its localization and diffusion. Early and combined treatment by general surgeon, radiotherapist and orthopaedic surgeon will provide a longer survival rate and relative physical and psychological well-being for the patient. Following the diffusion on surgical techniques designed to cope with tumor in different bones the wait-and-see attitude of the past has been abandoned. More vigorous attempts to excise metastatic tumours and aims at reconstruction and substitution of weightbearing bones by means of modern methods of osteosynthesis and application of prostheses, can be achieved. The more controversial clinical and radiological aspects and the results of 281 cases, seen at the Clinica Ortopedica of the University of Padua, are illustrated.

Adult↗

Acute spontaneous subdural haematoma. Description of four clinical cases.

Four cases of acute spontaneous subdural haematoma are described. A review of the literature reveals the rarity of this pathology. The several etiological possibilities are discussed. The clinical onset may simulate other cerebrovascular diseases. The prognosis is correlate to the neurological findings at the operations.

Adult↗

The role of TCD in hemodynamic evaluation of cerebral AVMs.

The cerebral AVMs have a considerable hemodynamic complexity and the transcranial doppler sonography may now provide noninvasively accurate hemodynamic information about these vascular lesions. It provides hemodynamic data like blood flow velocity on feeding arteries, intracranial steal phenomena, cerebral autoregulation disease as illustrated in 19 patients.

Adult↗

[Long-term non-deforming urinary infections in childhood. 2. Proposed treatment and results].

In the second part of the Authors work, they report the results obtained in the treatment of 85 female children with recurrent non malformative urinary tract infections. The first group of 15 female children had been treated with phenoxybenzamine and urinary chemyotherapycs with little satisfaction. The other two groups, both of which consisted of 35 children, one group was treated with only chemyotherapycs and the other with chemyotherapycs associated to oxybutynin chloride. The best results were obtained in the last group regarding the improvement of the symptoms and earlier and higher incidence of sterilization of the urine. At the same time in this group the maximum cystometric capacity and vesical compliance were brought back to normal and the detrusorial instability disappeared.

Anti-Infective Agents, Urinary↗

[Ureterocele: study of 66 cases observed in 60 children].

Ureterocele is an unfrequent urinary malformation in pediatric age, but frequently it is clinically severe. Ureterocele in a double pyelo-ureteral system often presents very difficult treatment problems not uniformely dealt with. Authors report their experience with 66 ureteroceles observed in 60 children; more than a half of which were less than one year old. In the authors experience simple ureterocele does'nt give any surgical problem. On the contrary ectopic ureterocele, almost always associated with a pyeloureteral duplication, frequently gives some problems of surgical treatment. Treatment is always individualized but in our experience the best results have been achieved with unroofing of the ureterocele and upper heminephoureterectomy in one stage. This treatment can be used successfully in the majority of ectopic ureteroceles in pediatric age.

Adolescent↗

[Long-term non-malformative urinary infections in children. (I)].

Non malformative long term urinary tract infections affect above all the female sex. The specific anatomic conditions explain only in part the predisposition for the female sex. Other determinants are the individual susceptibility and bacterial virulence. The authors studied 169 pediatric patients with recurrent urinary tract infections; of which 159 where females. The study of the blood group in 70 patients showed a net predominance of the groups B and AB. About one-third of the patients studied presented a scarce symptomatology or complete absence. The urodynamic study in 120 patients has revealed an abnormal pattern in more than 80% of the cases. According to the authors the abnormal urodynamic pattern is related to the long-term infection and is reversible in the cases which are curable. In about one-third of the cases with long-term infections which are resistent to the therapy, the cystoscopy has revealed a cystitis cystica. The study carried out by the authors permits precise indications on the specific tests that must be effectuated in this particular type of pathology and the indications of treatment.

Adolescent↗

[Tissue expansion in head and neck regions].

The Authors describe their experience with the use of 56 tissue expanders implanted in the head and neck regions of 45 patients observed in a follow-up of an average of 25 months. They emphasize the various possibilities of reconstructive surgery with the use of tissue expanders and the different mental approach required in order to organize surgical when this technique is employed. The criteria used in the selection of the type of tissue expanders is outlined and useful advice concerning the formulation of a surgical plan which employs the most favourable approach in making to avoid poor functional or aesthetic results or secondary complications is presented. Furthermore the surgical technique used to obtain adequate pockets for the insertion of tissue expanders in the different anatomical areas of the head and neck is described. The Authors affiem that in order to avoid damage to the surrounding neurovascular structures and to obtain good tissue expansion, the correct level of dissection is imperative. The options of using different anatomical areas during reconstructive surgery are discussed. For example, the insertion of a tissue expander in the forehead permits the availability of a large amount of usable tissue during nasal reconstruction, thus leaving the donor area without tension and with minimal scarring. Many different causes of baldness can be treated with the use of tissue expanders, such as posttraumatic injury, burns or infections. Tissue expansion can be utilized in the cheek area for the reconstruction of the lower eyelids, the paranasal and the mandibular area. Tissue expanders used in the cervical area can be utilized for reconstructive surgery of the lower lip or the mandibular area. In addition, the Authors discuss possible complications of this technique such as infection, suture distension and tissue expander extrusion. Recommendations are discussed in order to prevent these major complications. Having reviewed their personal experience the Authors feel they can confirm the reliability of this revolutionary technique in the field of plastic and reconstructive surgery. The use of tissue expanders permits the surgeon to obtain improved functional and aesthetic results which only a few years ago were not conceivable.

Female↗

[Macromastia in adolescents: notes on clinical aspects and therapy].

The surgical correction of macromastia is justified on both physical and psychological grounds. Hypertrophy of the breast may alter the development of the body, causing severe damage to the spinal cord. It may also condition the psychological or mental development of the patient, even going so far as to bring about fully fledged psychoses. The definitive scars of the surgical correction are generally accepted by the patients.

Adolescent↗

Electrophysiological (EEG-SSEP) monitoring during middle cerebral aneurysm surgery.

SSEPs were monitored during 38 procedures for aneurysms of the middle cerebral artery. In 13 selected patients intraoperative barbiturate protection with sodium thiopental was performed during temporary M1 occlusion. Combined EEG monitoring, showing burst suppression typical pattern of electrical cortical activity, allows a minimal dosage (3-6.5 mg/kg) of thiopental to achieve brain protection. Any patient with TYPE I SSEP changes had a new postoperative neurological deficit. Five patients during temporary middle cerebral artery clipping showed TYPE II SSEP changes and only one, not achieving burst suppression EEG pattern, had transient postoperative neurological deficit. In two other patients, a progressive worsening of TYPE II SSEP was observed; this was due to excessive brain retraction without brain protection and had a prolonged postoperative neurological deficit. Four patients showed TYPE IV SSEP changes during temporary M1 occlusion, one of whom was a 52-year-old woman, who, in spite of brain protection with thiopental, had serious postoperative neurological sequelae. In this patient N20 amplitude and central conduction time did not have full recovery to the preocclusive values. This study suggests that combined electrophysiological monitoring may reduce complications due to excessive retraction of cerebral tissue, make temporary clipping safer and improve the results of middle cerebral artery aneurysm surgery.

Adult↗