Search PubMed⌕ Search

Biomedical subjects

F Manfredini

Publications and source records attributed to F Manfredini.

23 records · Page 2Linked to original sources
PubMed1989

Reduction of Hb levels during the racing season in nonsideropenic professional cyclists.

Hematological variables of 40 professional cyclists, all receiving intravenous iron supplementation, were followed during a 15-month period. Mean values for red blood cells (RBC), hemoglobin (Hb), and hematocrit (Ht) were significantly lower during the racing season (RS) than during the nonracing periods (NRP) (RBC: RS = 4.53 +/- 0.34 millions/mm3, NRP = 5.09 +/- 0.36 millions/mm3; line 7 of abstract: Hb: RS = 14.2 +/- 0.9 g/dl, MRS = 15.2 +/- 0.9 g/dl; Ht: RS = 40.7 +/- 2.7% NRP = 44.4 +/- 2.9%; P less than 0.001 for all). However, mean values for ferritin and mean corpuscular hemoglobin (MCH) were significantly higher during the racing season (ferritin: RS = 422 +/- 398 ng/ml, NRP = 311 +/- 321 ng/ml, P less than 0.05; MCH: RS = 31.5 +/- 1.3 pg, NRP = 30.0 +/- 1.4 pg; P less than 0.001). These results suggest that the reductions in RBC, Hb, and Ht found in professional cyclists during the racing season are not the consequence of a diminution of iron stores but rather of reduced erythropoiesis and increased RBC destruction.

Anemia, Hypochromic↗
PubMed1987

Chronobiologic aspects of recurrent transient ischemic attack.

An epidemiologic study was conducted from 1979 through 1984 on subjects presenting transitory ischemic attacks (TIA) and admitted into our Institute. We investigated year, season, month, day, and hour of every attack on 80 patients aged between 51 and 88 years. Time-series analysis showed a seasonal pattern of disease onset in early spring. Peaks occurred in March-April, and isolated peaks were also detected in January and October. Concerning TIA-onset day, we observed a peak distribution in the last 10 days of the month. Data on the hour of onset, according to single cosinor (mesor +/- SE = 2.67 + 1.13; amplitude +/- SE = 2.57 + 1.13), yielded a significant (P less than 0.05) acrophase. The acrophase is at -135 degrees (-93 degrees, -245 degrees) for tau = 48 hr.

Aged↗
PubMedDate not supplied

Standard melatonin intake and circadian rhythms of elite athletes after a transmeridian flight.

Many transmeridian travellers, including top athletes, regularly take melatonin to reduce negative jet lag symptoms. Standard (rather than individually tailored) doses are often used. We examined the effects of a standard dose of melatonin on the body temperature rhythms of 12 elite biathletes (eight men and four women) after an eastward transmeridian flight to an international competition. The different effects on body temperature rhythms in men versus women underscore the need for personalized dosing schedules to avoid potential undesirable consequences.

Adult↗
PubMedDate not supplied

[Prevalence of risk factors and prevention of coronary disease in a population of construction workers of the Province of Bergamo].

Authors describe the prevalence of cardiovascular risk factors among 1.348 construction workers, enrolled in a five years lasted health surveillance program. Our results confirm both the high prevalence of cardiovascular risk factors and the need of further examinations other the clinical, laboratory, electrocardiogram and chest X, in order to point out a correct diagnosis and evaluate the fitness to job. Furthermore, we underline the usefulness of training in health education for the prevention of cardiovascular disease, considering the low extent to which individuals perceive their own risk.

Adolescent↗