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Biomedical subjects

F Mandell

Publications and source records attributed to F Mandell.

At least 37 records · Page 2Linked to original sources

Cot death among children of nurses. Observations of breathing patterns.

Research into cot death has recently been focused on a search for pre-existing chronic abnormalities rather than on the immediate events before death. Because nurses are trained observers, 30 nurses who had lost children by cot death were questioned. In particular, they were asked about any respiratory symptoms which had been present in the absence of respiratory tract infection. Some (37%) of the nurse mothers had noted unusual respiratory events (wheezing, apnoea, irregular respiration, or cyanosis) in their children during the early months of life. Only 6% on non-nurse mothers who similarly had lost children recalled respiratory difficulties. None of the 60 nurse mothers with healthy infants gave a history of respiratory difficulties in the absence of infection. The importance of taking a careful history from any parent who loses a child by cot death is stressed.

Humans↗

Observations of paternal response to sudden unanticipated infant death.

Support provided to families experiencing the loss of an infant to sudden infant death syndrome has focused on the description of maternal bonding and the consequences to the mother. However fathers also develop significant relationships with their infants, and their responses to the unanticipated loss of their children may be different than those of mothers. In this study 28 fathers who lost infants to SIDS appeared to have identifiable patterns of behavior which were more peculiar to men: (1) the necessity to "keep busy" with increased work; (2) feelings of diminished self-worth; (3) self-blame because of lack of "care" involvement; and (4) a limited ability to ask for help. That men should be stoic and less emotional and that one need not be concerned with the reactions of fathers appears to be a reflection of societal attitudes. However, these paternal behaviors, which emerge at a time of crisis and which obstruct full expression of grief, may unwittingly be promoted by medical and health care providers who are anxious to help fathers fulfill societal expectations of masculine strength.

Adolescent↗

Major coagulopathy and "nonpoisonous" snake bites.

Two florid examples of disseminated coagulopathy following the bite of a rear-fanged snake (normally considered "nonvenomous") are reported. The posibility of clinically significant cases of snakebite envenomation due to "harmless" snakes in the United States is raised because of the diagnostic and therapeutic implications.

Antivenins↗

Acute neonatal subdural hematoma following breech delivery.

We describe two term infants born by complicated breech deliveries, each of whom suffered an acute subdural hematoma. Both infants required repeated subdural taps; in one case a parietal burr hole was needed. Despite stormy neonatal courses, follow-up examination of the first infant at 26 months showed him to be normal, and in the other only a mild left esotropia was found at 22 months. Acute neonatal subdural hematoma is rare, but symptoms and signs are distinctive and the condition is remediable; immediate recognition and treatment is important.

Acute Disease↗

Sudden infant death syndrome. The disease and its survivors.

Sudden infant death syndrome (SIDS) is a peculiar entity in that the self-condemning reactions of the surviving family go far beyond the death itself. The parents should be helped to understand that SIDS is a disease, even though the mechanism of death is not known, and that it is neither preventable nor predictable. Surviving siblings should not be excluded from the mourning process and should be reassured about their good health and blamelessness in causing the death. If parents defer having another child until the grief process is complete, the psychologic environment for subsequent children will be healthier.

Child, Preschool↗

Erythromelalgia.

Erythromelalgia is an extraordinary disease which remains elusive in its pathophysiology and management. Victims suffer intense burning and redness of the hands and feet. In what appears to be the antithesis of Raynaud's disease, the pain is relieved by emersion in cold. A child with erythromelalgia is described whose symptoms began at age 3 years. Pharmacological management trials and thermography are incorporated in the report.

Child, Preschool↗

Sudden infant death syndrome and subsequent pregnancy.

In psychological conditions of mourning and guilt, women who have lost children often attempt to quickly conceive a "replacement" child. This study examines the subsequent pregnancies of 32 women whose children died of sudden infant death syndrom (SIDS). The expected rate of infertility in a normal population is 10%. Spontaneous abortion has an incidence of 12% to 15%. Among the 32 women attempting to conceive after the loss of their child, 10 (31%) had spontaneous abortions and 11 (34%) could not conceive after attempts for at least one year. This association between psychological and biological phenomena require special recognition by physicians who are advising parents who have lost children to SIDS. The management of these families includes compassion, understanding, and regard for the psychological environment of the subsequent pregnancy.

Abortion, Spontaneous↗

Treatment of atypical mycobacterial cervical adenitis with rifampin.

The clinical response of atypical mycobacterial cervical adenitis to standard antituberculous therapy has been disappointing. Surgical procedures in the anterior cervical triangle are difficult and often complete excision is impossible. In each of four children with atypical mycobacterial cervical adenitis in this study, the institution of rifampin therapy was followed by complete resolution. Previously rifampin, a well-tolerated, orally administered drug, had been used effectively with Mycobacterium tuberculosis. The place of this drug as a major alternative to surgical excision in cases of atypical mycobacterial cervical adentis is reviewed.

Antigens↗

The Mauriac syndrome.

Explore the source record for details and available documents.

17-Hydroxycorticosteroids↗

Changes in sleep position during infancy: a prospective longitudinal assessment.

CONTEXT: Prone sleeping by infants has been associated with an increased risk of sudden infant death syndrome. OBJECTIVE: To document the prevalence of and identify risk factors for prone sleeping during the first 6 months of life. DESIGN: Prospective cohort study. SETTING: Eastern Massachusetts and northwest Ohio. STUDY PARTICIPANTS: A total of 7796 mothers of infants weighing 2500 g or more at birth. MAIN OUTCOME MEASURES: Maternal and infant characteristics related to prone sleeping at 1 month and 3 months of age. RESULTS: Between 1 month and 3 months of age, prone sleeping increased from 18% to 29%. At 1 month, prone sleeping was associated with the following maternal characteristics: non-Hispanic black or Hispanic race/ethnicity, younger age, less education, and higher parity. At 3 months, switching from nonprone to prone position was associated with mother's race/ethnicity of non-Hispanic black (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.2-2.3) or Hispanic (OR, 1.5; 95% CI, 1.1-2.2); younger maternal age (compared with mothers >34 years: 18-24 years, OR, 1.6; 95% CI, 1.2-2.2; <18 years, OR, 2.2; 95% CI, 1.2-4.3); increasing parity (compared with 1 child: 2 children, OR, 1.5; 95% CI, 1.2-1.8; > or =3 children, OR, 1.7; 95% CI, 1.4-2.2); and infant sex (male sex, OR, 1.4; 95% CI, 1.2-1.7). CONCLUSIONS: If infant sleeping practices in the study communities are representative of practices throughout the United States, a substantial number of infants who slept nonprone at 1 month sleep prone at 3 months.

Adult↗