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Biomedical subjects

F Maitre

Publications and source records attributed to F Maitre.

At least 19 recordsLinked to original sources

[Vascular purpura in a patient with severe sarcoptic acariasis].

INTRODUCTION: The common cutaneous manifestations of human sarcoptic acariasis are erythematous and pruriginous papules. Vascular purpura in patients with scabies has rarely been reported. We report a case of vascular purpura in the presence of a transient elevation of anticardiolipin antibodies. CASE REPORT: A 79 year-old woman was treated with prednisone and chlorambucil for a lymphoma. She was referred to our institution for diffuse sarcoptic acariasis. Clinical examination showed a petechial purpura on her legs. Histology of two biopsies of purpuric papules showed non inflammatory thrombosis of the upper dermis vessels. Investigations revealed a transient elevation of anticardiolipin antibodies, moderate hyperhomocysteinaemia and blood eosinophilia. Treatment consisted in ivermectin and repeated applications of benzyl benzoate lotion. The purpura healed within one month, without specific treatment. DISCUSSION: Histological findings of sarcoptic acariasis with vascular purpura correspond to leukocytoclasic vasculitis. Focal glomerulonephritis has been reported. In our case, histopathology showed a non inflammatory thrombosis of the dermal vessels. We hypothesize that the anticardiolipin antibodies, hyperhomocysteinaemia and blood eosinophilia may have been the cause of vascular thrombosis.

Aged↗

[Duodenal somatostatinomas associated with von Recklinghausen's neurofibromatosis. Apropos of 2 cases].

Somatostatinomas are rare neuroendocrine tumors; they are essentially located in the pancreas and in the duodenum. The association with a neurofibromatosis type I is especially observed when the tumor is located in the ampulla of Vater. These tumors are not associated with a "somatostatin syndrome", but often present with gastrointestinal bleeding, abdominal pain and obstructive jaundice. The diagnosis is confirmed by immunohistochemical studies. The aim of this study is to report 2 cases of metastazing duodenal periampullary somatostatinomas associated with von Recklinghausen's disease and to discuss the prognosis of these tumors. Future genetic research are necessary as point out the familial feature of this association in one of our cases.

Duodenal Neoplasms↗

[Primary cutaneous neuroendocrine carcinoma (Merkel tumor). Clinical and therapeutic update apropos of 4 cases].

The clinical and pathological features of 4 cases of cutaneous neuroendocrine carcinoma are reported. There are unusual malignancies mostly observed in elderly, the prognosis is poor by loco-regional aggressivity and disseminated metastases. They are diagnosed by a pathologist: ultrastructural studies and immunohistochemistry support the diagnosis. A combination of a wild local excision, node dissection and post-operative radiation is recommended.

Aged↗

[Prenatal diagnosis of a placenta praevia percreta with color Doppler. A case report. Review of the literature].

Placenta praevia percreta, with bladder invasion, was diagnosed at 29 weeks of amenorrhoea with colour Doppler which visualized vascular bundles leaving the placenta and reaching the lower part of the bladder. These bundles were identified as including arterial elements with pulsed Doppler. The criteria for the diagnosis of placenta accreta with ultrasonography and colour Doppler have been presented in the literature. This prenatal diagnosis allowed adapted preoperative management and intensive care, however air embolism could not be avoided and the patient died at the end of the operation.

Adult↗

[Metastasis of breast cancer to a uterine leiomyoma].

The authors report a case of metastasis of cancer from the breast in a uterine leiomyoma. The metastases into the body of the uterus from extragenital cancers are rare. If they occur they are usually in the myometrium where they are asymptomatic and where the diagnosis is difficult, or in the endometrium where the diagnosis can be made by biopsy after curettage. A few rare cases of metastases in uterine leiomyoma have been reported in the literature. They can be the cause of very sudden increase in size of fibroids with compression of the pelvic organs.

Adenocarcinoma↗

[Pheochromocytoma of the broad ligament].

The authors report a rare case where a pheochromocytoma which was not in the adrenal gland occurred in the broad ligament. A review of the literature resulted in only three published cases being found. When the symptomatology suggests that there may be a pheochromocytoma in the body one has to research where it is sited and one has to think of such a possibility if a tumour in the broad ligament is found during an operation, so that the risks of operating on these tumours can be lessened.

Adnexal Diseases↗