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Biomedical subjects

F Maddalena

Publications and source records attributed to F Maddalena.

51 records · Page 3Linked to original sources
PubMed1981

[Early hemodynamic changes after mitral valve replacement with the Hancock prosthesis].

In mitral valve replacement for mitral stenosis the persistence of a depressed cardiac performance immediately after operation has been outlined by several authors. The choice of a porcine central flow prosthesis, that has several theoretical advantages, should allow better acute hemodynamic results. Therefore ten patients have been studied by thermodilution methods and the variations in their hemodynamic parameters has been evaluated with a paired T-Test. Results confirm the persistence of a depressed cardiac function throughout the time span of the study (36 hours). This behaviour could be related to the use of Kirsch solution for myocardial protection. Therefore the authors compare a similar group of nine patients that underwent mitral valve replacement with differently designed prosthesis and the use of a St Thomas analogue cardioplegic solution. They conclude for the persistence, in the acute postoperative period, of an intrinsic myocardial dysfunction.

Adult↗
PubMed1980

Tricuspid atresia with double-outlet left atrium.

Clinical and pathologic findings of an unusual case of cardiac malformation are presented. The main features were those of atresia of the right atrioventricular valve associated with two distinct atrioventricular orifices connecting the morphologically left atrium to the underlying morphologically left ventricle. Other distinguishing characteristics were ostium secundum atrial septal defect, normally related great arteries, with the aorta arising from the main ventricular chamber and the pulmonary artery from the anterior and right-sided outlet chamber, and infundibular and valvular pulmonary atresia.

Abnormalities, Multiple↗
PubMed1975

[Anatomically corrected malposition of the great arteries (author's transl)].

Anatomically corrected malposition of the great arteries is defined as a trunco-conal malformation characterized by an aorta arising anteriorly from a morphologically left ventricle and by the presence of a subaortic muscular conus. This malalignment determines a conotruncal-ventricular discordance: d-loop and l-position or l-loop and d-position of the aorta. Two additional cases of this very rate lesion are reported, both associated with left juxtaposition of the atrial appendages, tricuspid atresia, ventricular malrotation and destrocardia in situs solitus with d-loop. Because of the high frequency of this association, observed also in the majority of the previously published cases, its morphogenetic significance and implications are discussed.

Dextrocardia↗
PubMed1975

[The congenital coronary artery fistula. Observations on seven cases (author's transl)].

The authors report seven cases of congenital coronary artery fistula observed in the Cardiology Department of Padua Medical School. The cardiopathy, the anatomo-histological characteristics, evolution and embriology are described. The anamnesic, clinical, electrocardiographic, X-Ray, phonocardiogram, haemodynamic, and contrastographic findings for each case are given. They are discussed and interpreted in the light of the pathophysiology of the disease.

Adolescent↗
PubMed1975

[Postoperative bacterial endocarditis after cardiac prosthesis (author's transl)].

The infection of an endocardial prosthesis, either valvular or septal patch, is a frequent and dangerous post-operative complication. Eleven patients having postoperative endocarditis (9 on valve prosthesis and 2 on ventricular septal patch) are the subject of this paper. Six of the 7 infected "early" had Gram-negative bacteria in the blood cultures, while staphylococus aureus, streptococcus viridans and klebsiella pneumoniae were responsible for 3 of the 4 "late" infections. In 2 patients, one "early" and one "late" the causative bacteria were not identified. The definite prevalence of Gram-negative flora in post-operative endocarditis may have been facilitated by the routine use of antibiotics after open-heart surgery. Three of the 11 patients survived, one after replacement of the infected prosthesis and two after prolonged specific antibiotic treatment. On the basic of this experience, compared with other written reports, the authors propose to treat postoperative endocarditis medically for approximately 5 weeks, with full doses of specific antibiotics, reserving for surgical treatment only the cases of prosthetic malfunction, left atrial thrombosis, peripheral embolization and in those patients where the medical treatment fails.

Adolescent↗