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Biomedical subjects

F M Solivetti

Publications and source records attributed to F M Solivetti.

17 recordsLinked to original sources

[Seminal vesicles: echographic findings in 244 subjects. Evaluation of anatomic data and correlations with pathologic prostatic-vesicular parameters].

Over a 2-year period (1989-90), about 400 cases were examined (out of nearly 2,500 US examinations of the prostate), 244 of which had subsequent bioptic, surgical or autoptic confirmation. This paper reports the anatomic, clinical and pathologic data relative to the seminal vesicles of 244 subjects who underwent transrectal US of the prostate for different clinical indications. Our biometric values were slightly different from those reported in literature, the latter being based on autoptic findings. Agenesis and monolateral ectopia were confirmed to be extremely rare: 4 cases only (1.6%) in our series. A typical finding was the nearly perfect symmetry; in size and structure, of the two seminal vesicles in the same subject; as a matter of fact, a loco-regional pathologic condition was detected in all the patients (14) with asymmetry. A hundred per cent agreement was observed between the US patterns of the seminal vesicles and the prostatic patterns in case of acute/subacute prostatic inflammation involving also the 2 glands: this parameter can be used to follow the clinical course of the inflammatory process.

Adult

Transperineal vesiculodeferentography under ultrasound control: first experiences.

Vesiculodeferentography (VDG) plays an important role in diagnosing male infertility and staging of prostatic cancer; the techniques of performing the examination are, today, well codified: 1) retrograde, by endoscopic cannulation of ejaculatory ducts; 2) anterograde, by cannulation of the deferent duct surgically prepared at the scrotum. In order to avoid the difficulties of the first method and the risks in the second (like stenosis and fibrosis of the deferent duct) we propose a new simple and safe method based on the direct transperineal puncture of the seminal vesicle under direct echographic control with a transrectal probe. We have studied 16 patients, mainly in order to stage prostatic cancer; the procedure was easy to perform, well tolerated and without consequences at seminal level. It required only 30 minutes, without anaesthesia and with a very low cost. The method permits a clear visualisation of anatomical structures and of possible pathologies with particular reference to vesicular invasion by a prostatic cancer.

Catheterization

[Echo-guided needle biopsy of the thyroid. An assessment of 52 thyroid neoplasms found in 1042 consecutive patients].

The authors report on a series of 1,043 fine-needle biopsies of the thyroid performed under US guidance; the patients had been selected for thyroid pathologic conditions. Fifty-two neoplasms were observed (46 papillary carcinomas, 1 medullary carcinoma, 2 follicular carcinomas, and 3 metastases), which had been detected by cytology and confirmed by histology or autopsy. The authors focus on 46 cases of papillary carcinoma: their US features were studied which, through a correlation of variables, allow a quick and "safe" recognition of the type of carcinoma (papillary carcinomas account for nearly 60% of thyroid neoplasms). Tumor echogenicity and outline, and the presence/absence of calcifications were evaluated: in most cases, papillary carcinomas presented as focal lesions (alone or associated with other goiter lesions), with irregular and blurred outline, no hypo/anechoic halo and, in about 1/3 of the cases, with calcifications and colliquative areas. In 17% of papillary neoplasms, metastases to loco-regional nodes were observable at US; in 3 cases the carcinoma did involve a loco-regional node but there were no US signs suggestive of it. The incidence of neoplasms on the total of fine-needle biopsies is 4.9%, while in a previous series of 3,038 fine-needle biopsies, without US guidance, on clinically detectable lesions, the figure was about 2%.

Adenocarcinoma

[Color Doppler in the diagnosis of malignant prostatic neoplasia. Preliminary results].

In the field ultrasonic diagnosis the application of color code to the duplex Doppler signal is without doubt the most up-to-date method. The common knowledge according to which all heteroplastic structures need a large quantity of O2 and provoke the formation of new vessels with the angiogenesis factor, with particularly rapid, and tumultuous fluxes due to the presence of shunt, is the basis for the use of color doppler in research on neoplasia in the initial phase. The authors submitted 11 patients considered at risk, to an echocolor Doppler study of the prostate, with a transrectal biplane probe of MHz. The exclusive application of ultrasonography grey scale, permitted the diagnosis of malignant neoplasia in 5 of these subjects. The following "color" exploration led to a cancer diagnosis in 10 patients. A bioptic check carried out through transperineal way color guided allowed the diagnosis of 8 'adenocarcinomas' and 1 undifferentiated CA.

Adenocarcinoma

[Transrectal echography and simultaneous uroflowmetry in the study of male urination. Considerations on 254 consecutive cases].

The authors report on a series of 254 consecutive male patients who underwent transrectal US, sometimes combined with uroflowmetry, for the study of micturitonal phase. 170 patients were studied with both techniques. In 118 patients, there was complete agreement between the two methods about presence and degree of flow obstruction; partial disagreement was observed in 48 patients and complete disagreement in 4. On 44/52 patients with partial/complete disagreement diagnostic cystouretrography was performed. Our results demonstrate high agreement between the two techniques, except in case of micturition deficit with columnar hypertrophic bladder and in obstructive pathologic conditions of anterior urethra.

Adult

[Calcifications of the prostate: a transrectal echographic study].

Prostatic lithiasis is a well know phenomenon. It has little clinical significance and is not easily shown by conventional radiography, which has poor sensitivity and specificity. The authors have studied 612 patients with both suprapubic and transrectal US in order to 1) assess US sensitivity and specificity and 2) report the frequency, spatial distribution, number and features of prostatic calcifications with special emphasis on differential diagnosis between prostatic neoplasms and chronic prostatitis. The authors have also studied the relationship between morphology and symptoms and the results agree with those reported in the scanty literature. The authors conclude that the parameters studied are directly related to age, except for a younger group with clear evidence of genital inflammation. The authors emphasize the impossibility to correlate morphology of prostatic calcifications with pathologic conditions: there are no specific symptoms clearly connected with calcification even though the inflammation is often associated with calcifications.

Calcinosis

[Ultrasound-guided prostatic biopsy using biplanar transrectal probe. Our experience].

In the last three years we performed more than 200 echo-guided prostatic biopsies using different probes. Recently, thanks to the availability of a bi-planar transrectal probe we have developed a technique that resulted simple rapid well accepted by the patients and above all able to center small prostatic nodules. We have studied with this technique 96 patients performing 120 biopsies. For the biopsy we used a 19 G cutting-needle introduced under local anaesthesia parallel to the probe (linear array) when the needle is on the target we turn on the axial view and we check the position with respect to the center of the lesion, then, returning to the sagittal view we perform 1 to 3 biopsies for microhistological and cytological examination. With this method we have reached a better accuracy of diagnosis.

Biopsy

[Peyronie's disease. Ultrasonic evaluation].

Peyronie disease, or Induratio Penis Plastica, is characterized by the presence of one or more fibrous plaques at the albuginea penis, on the cavernous bodies or on the intercavernous septum. First of all, Induratio Penis Plastica etiology is described, and its clinics and therapy. Past imaging methods are then considered (i.e. conventional radiology, xerography), and current ones (i.e. conventional radiology, cavernosography, CT and US). The authors report on their 4-year (1983-1987) experience with US in 62 males. Various different probes were employed, especially small-part 7.5 MHz probes. The results are similar to those reported in international literature. The use of high frequency probes allows the evaluation of focal hypoechoic lesions even in the early phase of the disease, thus helping make therapy more effective.

Adult

CT of ischemic infarctions in the territory of the anterior choroidal artery: a review of 28 cases.

The purpose of the present study was to examine the incidence, causal factors, and anatomic localizations of infarction in the territory of the anterior choroidal artery. We studied 28 patients who had CT evidence of infarction in this territory. The affected structures taken into consideration were the posterior limb of the internal capsule, the retrolenticular portion of the internal capsule, the internal portion of the globus pallidus, and the lateral thalamus. Three conclusions are drawn: that ischemic infarcts in the territory of the anterior choroidal artery are rare, representing 2.9% of all cerebral ischemic lesions in our material; that the incidence of a possible embolic origin is significant; and that the posterior two-thirds of the posterior limb of the internal capsule and the retrolenticular segment are the more frequently affected structures, and conversely, that the medial pallidus and the thalamus are less often involved.

Adult