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Biomedical subjects

F M Quinn

Publications and source records attributed to F M Quinn.

21 records · Page 2Linked to original sources

Endoscopic management of vesico-ureteric reflux in children with neuropathic bladder secondary to myelomeningocoele.

Vesicoureteric reflux (VUR) is a major cause of morbidity and mortality in children with neuropathic bladders secondary to myelomeningocoele. The majority deteriorate with age and early treatment is necessary to avoid this. Endoscopic subureteric Teflon injection ("STING") allows correction of reflux in small children who would otherwise be difficult to manage. The results of treatment of VUR in 41 ureters in 24 children with neuropathic bladders using "STING" are reported. All ureters had grade III-V VUR. Thirty ureters (73%) showed disappearance of reflux after one injection. Of the remaining 11, VUR disappeared in 7 after a second injection. Apart from failure, the only other major complication was septicaemia in one patient. The mean hospital stay was 1.4 days (1-8 days). At a mean follow-up time of 22 months there was radiological improvement in the upper renal tracts in 27 of the 37 (73%) in which VUR disappeared, none has deteriorated and there has been only one relapse. These results suggest that "STING" should be considered as the method of choice in the management VUR in children with neuropathic bladder in view of the problems associated with open operation in these children.

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Parental attitudes to the unclosed open neural tube defect.

Recent years have seen a trend away from the immediate closure to delayed or nonclosure of the back lesion in open neural tube defects (ONTD). Parental attitudes towards this more conservative surgical policy have not been investigated. We therefore surveyed 70 families in Northern Ireland of children who are still alive, over six months of age who had an ONTD which was not surgically closed immediately after birth. Fifty-eight parents (84%) responded. Most parents (84%) had no difficulty in handling or dressing the back, but three-quarters felt that the lesion was painful and 41% felt that its appearance was disturbing to other members of the family. In those who had delayed closure (n = 15) all parents confirmed that the child was more comfortable and easier to handle afterwards. Eleven of them (73%) felt that the child was more acceptable to the rest of the family and that surgery should have been carried out earlier. A third preferred immediate closure "to make the child more comfortable" and to "improve the general quality of life". However, 46% did not want surgery for fear of upsetting the status quo. This survey suggested that parental attitudes towards the open back lesion differ greatly and that these views should play a greater role in the decisions which influence the timing of closure of ONTD.

Attitude↗