Biomedical subjects

F M Levine

Publications and source records attributed to F M Levine.

11 recordsLinked to original sources

PubMed1983

Stimulus-seeking behavior in hyperactive and nonhyperactive children.

Auditory and visual stimulus-seeking behavior was measured in hyperactive and nonhyperactive youngsters. The design controlled for motor activity level. The results indicate that hyperactive children preferred auditory stimulation more than the control children. There were no differences in stimulus-seeking preferences in the visual modality. The groups did not differ in motor activity. It was concluded that abnormally high needs for stimulation are important in hyperactivity.

Arousal↗

PubMed1981

Are movement disorders the most serious side effects of maintenance therapy with antipsychotic drugs?

This paper concerns assessment of the full range of risks associated with prolonged use of antipsychotic medication. It is generally accepted that the most common side effects of drug therapy involve motor problems. Movement disorders arise because antipsychotics, in a substantial proportion of patients, disrupt the basal ganglia. The basal ganglia, however, are involved in much more than simply motor control. Specifically, this neural system has been implicated in sensory reactivity, attention, memory, and cognition. It follows from this that antipsychotic drugs, in addition to causing motor problems, might also disrupt complex psychological processes.

Animals↗

PubMed1979

Implications of basal ganglionic dysfunction for schizophrenia.

This paper is addressed to presenting evidence that the basal ganglia are involved in mediating schizophrenia. Data from the experimental and clinical literature suggest a basal ganglionic role in higher cognitive processes, affect, and attention. Deficits of these same factors serve to characterize the major symptoms of schizophrenia. Moreover, psychiatric patients tend to have frank motor problems characteristic of basal ganglia lesions and pathological conditions of the basal ganglia manifest psychiatric difficulties as a major symptom. Taken together, these data are in accord with the hypothesis that some dysfunction involving the basal ganglia is a major factor in schizophrenia.

Affect↗

PubMed1973