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Biomedical subjects

F M Grignolo

Publications and source records attributed to F M Grignolo.

21 records · Page 2Linked to original sources

[Variations of intraocular pressure induced by psychological stress (author's transl)].

Peculiar psychic reactivity of glaucomatous patients detected clinically and widely treated in the literature, has led us to study the behaviour of intraocular pressure in normal and glaucomatous subjects when submitted to various stresses. The data obtained show that prolonged stress increases intraocular pressure in normal subjects, unlike shorter stress which only causes an increase of intraocular pressure in glaucomatous patients. The possible genesis of the phenomenon is discussed.

Adult↗

Fluorescence histochemical demonstration of adrenergic terminations in the human choroid.

With the existing literature on the aspects of anatomic and physiological ocular choroid membrane variables in mind, the authors verify the possibility of applying the methods of Axelsson et al and of Lindvall and Bjorklund, as simplified by Furness and Costa for fluorescent microscopy, to the study of human choroid nerve topographic distribution. The material for the study was obtained from three human eyeballs, two enucleated because of malignant melanoma of the choroid and one because of neoplasia of the ciliary body. A binocular dissecting microscope was used. A fluorescent microscope was used to observe the histological specimens and photographs were taken. The following results are presented and discussed: 1) the fluorescent paravascular nervous fibres and periarterial nervous plexuses divided into preterminal and terminal fibres; 2) in the suprachoroidal layer, there were small groups of polygonal nervous branches with or without this connection; 3) the most intervasal plexus development was in the posterior part of the vascular layer with preterminal and terminal fibres, 4) in the intervascular space, melanocytes and free adrenergic nervous terminations were observed; 5) adrenergic fibres were not observed in the choriocapillaris of the choroid membrane; 6) there were adrenergic neurons in the vascular layer.

Choroid↗

Long-term refractive and phoric changes in visual display unit (VDU) operators.

PURPOSE: This study assessed the phoric and refractive changes possibly caused by visual display unit (VDU) activity. METHODS: In a longitudinal trial nearly 6000 VDU operators received two ophthalmological examinations at intervals ranging from 34 to 43 months. The findings from the two examinations were correlated to VDU work (hours daily and years of VDU work), age and sex. RESULTS: Changes in the refractive state seemed to be mainly age-related. There was a slight tendency toward hyperopia (imbalance of latent hyperopia). CONCLUSIONS: In the analysis of ocular motility, the results show no worsening capable of causing a definitive change from heterophoria to heterotropia. Heterophoric subjects, however, tend to improve both with regular office work and with additional VDU activity.

Adolescent↗