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Biomedical subjects

F M Danza

Publications and source records attributed to F M Danza.

At least 37 records · Page 2Linked to original sources

[Hemobilia: comparison of diagnostic technics. Considerations on 14 patients].

Fourteen cases of hemobilia of traumatic (six), vascular (six) or neoplastic (two) origin were reviewed. Eleven patients obtained correct diagnosis only be integration of at least two diagnostic procedures out of Ultrasonography, Computed Tomography, arteriography and cholangiography. Although US and CT are extremely useful as screening procedures, correct diagnosis should be only possible by integration of more diagnostic technics. Arterial embolization represents a successful alternative to surgical intervention; moreover US may also be helpful for follow-up of treated patients.

Cholangiography↗

[Comparison between isteropac and a new non-ionic contrast medium for hysterosalpingography (B-15000)].

The authors refer the results of a double blind hysterosalpingographic study with a traditional ionic contrast medium (Isteropac) and a new non-ionic one (B-15000). Both the contrast have provided good quality images, without significant intolerance. Moreover the new non-ionic contrast medium has shown an easier utero-tubal transit with a sensible reduction of the examination length and a better diagnostic result.

Adult↗

Rounded atelectasis: considerations on its radiological diagnosis.

Rounded atelectasis is a particular form of peripheral lung collapse, adjacent to the pleura and causing a pulmonary opacity, often resembling a neoplastic mass. Its early identification avoids further investigations with more invasive techniques, especially unnecessary thoracotomy. The aim of this report is to contribute some case studies to the body of information which characterizes this radiographic and tomodensitometric entity; aspiration biopsy can possibly be performed to resolve diagnostic uncertainties.

Adult↗

[A new medico-nuclear outlook for the diagnosis and treatment of pheochromocytomas: 131I-meta-iodobenzylguanidine (131I-MIBG). Comments on results obtained].

The diagnostic and therapeutic potential of 131I-MIBG, the new imaging agent with structural similarity to norepinephrine, was evaluated in 23 patients with a suspect pheochromocytoma. Seven out of 8 benign pheochromocytomas (2 ectopic) were correctly localized with 131I-MIBG scintigraphy (1 false negative). In 2 catecholamine-secreting malignant pheochromocytomas both the primary tumor and the metastases (1 case) were demonstrated. One uncommon case of dopamine-secreting malignant pheochromocytoma, as expected, was not shown. In the remaining 12 cases, found to be "normal" after completing the work-up, distribution of the radiopharmaceutical was evaluated using a semiquantitative grading system. 131I-MIBG scintigraphy proved to be a non invasive and accurate (95%) diagnostic modality, specific for neuroadrenergic tumors. The treatment with 131I-MIBG was also carried out in 2 malignant pheochromocytomas with encouraging results.

3-Iodobenzylguanidine↗

[Possibility of using 131I-meta-iodobenzylguanidine in the diagnosis of neuroendocrine tumors differing from pheochromocytomas].

The results obtained using 131I-MIBG to diagnose different neuroendocrine tumors in 17 patients are discussed. In 8 of the neuroblastomas studied the examination gave a wide spectrum of scintigraphic results according to the various stages of evolution of the tumors, thus supplying additional useful information for metabolic treatment. Contradictory data were obtained in 5 cases of medullary cancer of the thyroid. The overall results were unexpectedly negative for 2 carcinoid tumors and, as expected, negative for 2 ganglioneuromas. These data confirm that 131I-MIBG is a non invasive, reliable and easy-to-perform technique which is no longer limited to the diagnosis of pheochromocytomas, but can also be used for the diagnosis of other tumors derived from neural crest cells.

3-Iodobenzylguanidine↗

[Peritubal adhesions and hysterosalpingography].

Hysterosalpingography cannot directly show pelvic adhesions due to pelviperitonitis, salpingitis, perimetritis or parametritis. Nevertheless this method is able to evidence an eventual tubal involvement by adhesive tissue. Located pools of contrast medium around the tubae is a well known radiological sign, but not the only nor the most frequently one observed. If the adhesions include the proximal end of the tubae, the contrast pooling may be absent. This paper analyzes, in controlled series of patients with pelvic adhesions, all the hysterosalpingographic signs which can indicate an adhesive tubal involvement.

Adult↗

Hepatic hemangiomas on 33 patients. Evaluation by ultrasound, nuclear medicine, computed tomography and angiography.

33 cases of hepatic hemangioma evaluated by various diagnostic tools (ultrasound, nuclear medicine, computed tomography and angiography) are reported. Nuclear medicine is the least sensitive and specific (only a report of a lacunar area). Ultrasound sensitivity is very high, also for lesions below 2 cm. Specificity initially very low, is now going to increase according to the operator's experience. Computed tomography shows good sensitivity and provides typical signs of hemangiomas, especially in the largest tumors. Angiography was not demonstrated in all cases (2 false-negative in lesions below 2 cm). In fact, in smaller hemangiomas often fibrotic tissue is predominant and vascular anomalies may not appear. When surgery is not performed, ultrasound is recommended as non-invasive follow-up.

Adult↗

Rupture of multiple hepatic adenoma and oral contraceptive use: a case report.

A 38-year-old woman was seen with a hemoperitoneum caused by rupture of a hepatic adenoma of the right lobe. The patient had been taking oral contraceptives for ten years, but discontinued their use three years previously. During the postoperative course a second adenoma of the contralateral lobe, not diagnosed at the first operation, ruptured. The relationship between oral contraceptive use and hepatic cell adenoma is briefly reviewed.

Adenoma↗

Thoracic extramedullary hematopoiesis: evaluation by conventional radiology and computed tomography.

4 cases of extramedullary hematopoiesis (EH) in the posterior mediastinum in patients affected with serious chronic anemia are presented. The contribution of conventional radiology and computed tomography (CT) to the assessment of an exact diagnosis, is discussed. The CT images are above all characterized by the presence of typical bilateral, asymmetrical paravertebral hyperdense masses (about 45 HU). Besides, a striated aspect of the vertebral bodies is common. For a rather sure diagnosis of EH in patients with chronic anemia, a conventional chest X-ray and CT of the thorax is sufficient. Biopsy and thoracotomy should be avoided.

Adult↗

[Uncommon locations of celomic cysts: a possible cause of error in mediastinal radiology (author's transl)].

Five cases of uncommon locations of mediastinal celomic cysts are presented. All cases were surgically proved. The importance of these locations in the differential diagnosis of mediastinal masses is stressed. The evaluation of their inner structure by computerized tomography is, without doubt, the best progress in radiological diagnosis of the mediastinum. This method allows, atraumatically, to confirm or exclude the cystic nature of the lesion in one with its precise spatial localization.

Adult↗