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Biomedical subjects

F M Burkle

Publications and source records attributed to F M Burkle.

13 recordsLinked to original sources
PubMed1991

Triage of disaster-related neuropsychiatric casualties.

Existing triage algorithms consider, for the most part, only the primary casualty with physical trauma. Algorithms fail to appreciate the primary, secondary, or tertiary neuropsychiatric casualty. Research advances on neuropsychiatric casualties must link with the mandates of emergency medical services and disaster management to improve triage sensitivity and specificity. Early recognition and management of neuropsychiatric casualties will diminish the potential for long-term consequences. Expanded triage algorithm supplements are proposed to improve the recognition of those victims at risk.

Disasters↗
PubMed1988

Isolated axial volvulus of a Meckel's diverticulum.

A 3.5-year-old boy presented twice within 36 hours to an emergency department with worsening abdominal distress. At surgery, an isolated axial volvulus of a Meckel's diverticulum was found. This finding has been reported three times in the last 20 years and has involved only adult patients. Meckel's diverticulum, although uncommon, can be extremely serious. Its presentation and pathophysiology are reviewed.

Adolescent↗
PubMed1987

Plasma atropine concentrations via intravenous, endotracheal, and intraosseous administration.

To date, there have been limited studies on the pharmacokinetics of intravenous atropine and no pharmacokinetic studies on the endotracheal or intraosseous administration of atropine. This study examines the time to peak plasma concentration of atropine following intravenous, endotracheal, and intraosseous administration in anesthetized monkeys using a triple crossover design. Plasma atropine was assayed by a radioreceptor method. The time to peak plasma concentration of atropine was shortest with intravenous administration; and longest with endotracheal administration. The mean plasma concentration of atropine was significantly higher in intravenous administrations than in endotracheal administrations at 0.75 and 2 minutes; compared to that noted in intraosseous administrations, the concentration was significantly higher only at 0.75 minutes. The mean plasma concentration of atropine administered intraosseously was significantly higher than that of endotracheal administrations at 5 minutes and was greater than that of intravenous and endotracheal administrations for the samples collected from 5 to 30 minutes. The endotracheal and intraosseous routes provide alternatives to the intravenous administration of atropine when intravenous access is limited or not available.

Animals↗
PubMed1987

Code organization.

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Emergency Service, Hospital↗
PubMed1986

Late death in tricyclic antidepressant overdose revisited.

We report a late death following the ingestion of amitriptyline. A 46-year-old woman presented to the emergency department with coma, hypotension, tachycardia, and a prolonged QRS interval after the ingestion of a large quantity of Elavil. She was managed with aggressive supportive care, multiple doses of oral charcoal, and charcoal hemoperfusion. The patient's ECG and hemodynamic status returned to normal within 24 hours. Despite an apparent total recovery, she suddenly sustained a cardiorespiratory arrest and died 33 hours after ECG normalization (at 57 hours after admission). This case brings into question the feasibility of ceasing ECG monitoring in tricyclic antidepressant overdoses once the ECG has stabilized, especially in patients with a history of chronic usage. A possible explanation for late sequelae is the myocardial cell binding and depressant effect of preexisting therapeutic TCA medication.

Amitriptyline↗
PubMed1986

Addisonian crisis in an adolescent female: a case report.

Acute adrenal insufficiency is rarely diagnosed in the pediatric age group. In this case report, an 11-year-old female with three previous admissions for dehydration was seen for dehydration and shock. Adrenal insufficiency was considered as a working diagnosis in the emergency department. Rapid intervention with intravenous hydrocortisone and fluid resuscitation resulted in a good outcome.

Acute Disease↗