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F M Baer

Publications and source records attributed to F M Baer.

56 records · Page 4Linked to original sources

MRI assessment of coronary artery disease.

With the application of magnetic resonance imaging (MRI) in clinical cardiology, important tools have been added to the currently available techniques for the evaluation of coronary artery disease (CAD). Technical advantages of MRI in comparison to established imaging techniques are the excellent spatial resolution, the characterization of myocardial tissue and the potential to acquire a three dimensional set of data. This allows the accurate assessment of left ventricular mass and volume and the determination of systolic wall thickening and wall motion abnormalities. Myocardial perfusion, metabolism and inducible myocardial ischemia with the use of pharmacological stress also can be assessed by MRI. Future technical improvements in real-time imaging and development of non-invasive visualization of the coronary arteries and coronary artery bypasses will constitute a considerable progress in clinical cardiology. A particular strength of MRI is the potential to encompass cardiac anatomy, function, perfusion, metabolism and coronary angiography in a single study. The replacement of multiple diagnostic tests with a single MR study allowing to assess different aspects of CAD may have a major impact on cardiovascular health care economics.

Cardiac Volume↗

MRI assessment of myocardial viability: comparison with other imaging techniques.

The identification of dysfunctional but viable myocardium in patients with coronary artery disease with or without a history of myocardial infarction is of paramount clinical importance since viable myocardial areas are most likely to benefit from revascularization, whereas revascularization of scar tissue will not lead to improvement of left ventricular function. In some patients cardiac catheterization itself already provides important clues to the presence of viable myocardium based on the degree of wall motion abnormalities, post-extrasystolic improvement of wall motion, the presence of collateral vessels or persisting angina in a patient with single vessel disease. However, due to the complexity of viability assessment especially in patients with severely depressed left ventricular function and multi-vessel disease, viability tests are usually requested after the results of coronary angiography are known. Among the diagnostic armamentarium to identify viable myocardium the most established techniques are single photon emission computed tomography (SPECT), positron emission tomography (PET) if available and dobutamine stress-echocardiography. With the application of magnetic resonance imaging (MRI) in clinical cardiology an important and exciting diagnostic tool has been added for the prospective identification of viable myocardium for purposes of guiding therapeutic interventions in individual patients. This article reviews comparative studies between MRI and established imaging techniques like PET, SPECT and dobutamine-echocardiography with respect to the assessment of viable myocardium in patients with acute myocardial infarction and chronic coronary artery disease.

Angina Pectoris↗