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Biomedical subjects

F Luzza

Publications and source records attributed to F Luzza.

42 records · Page 3Linked to original sources

Asynchronous intraventricular recovery as a basis for apparent 'supernormality'.

Various mechanisms have been postulated for the supernormal phase of intraventricular conduction where relatively early impulses are conducted with normal intraventricular conduction and relatively late impulses with abnormal intraventricular conduction. The cases presented here illustrate how asynchronous recovery of conducting tissue may result in fortuitous momentary synchrony early on in the recovery phase with asynchronous conduction properties in the later phases of recovery. This will facilitate potential synchronous conduction early on in the cycle which would result in a normal QRS complex, and potential asynchronous conduction in the later phases which would manifest with a bundle branch block QRS complex.

Aged

Sinoatrial block with complicating sinoatrial reciprocation.

This presentation reflects an atypical manifestation of sinoatrial block in a patient with chronic renal failure and hyperkalemia (7.8 mEq/L). An allorhythmic distribution of P-P intervals permits the interpretation of sinoatrial block complicated by sinoatrial reciprocation.

Electrocardiography

[The retriggerable refractory period: a rare cause of apparent sensing malfunctioning in various types of VVI pacemakers].

The retriggerable Refractory Period (RP) is an anti-interference device that causes prolongation of the RP in the presence of rapid false signals. The device starts functioning when a suprathreshold impulse manifests during the second half of the RP of the pacemaker; in such a case the RP itself is retriggered, i.e., re-starts from the moment in which the retrigger occurs. As a consequence, the time during which the pacer cannot be recycled is prolonged. We report a case of unusual pseudo-malfunction caused by the retriggerable RP observed in a patient paced with a Lit 222 Sorin VVI pacemaker. Spontaneous QRS complexes coupled up to 480 ms appeared as not senses, i.e. did not reset the pacemaker, whereas complexes occurring at 510 ms or more from the spike provoked a normal recycling, and complexes coupled at 490-500 ms resulted in partial recycling. This pattern has been interpreted assuming that a spurious signal (probably an afterpotential) occurs shortly after the paced stimulus. Such a signal falls in the retriggerable RP, resulting in prolongation of the RP. Spontaneous QRS, thus, cannot be sensed until 480 ms from the paced impulse. The chest wall stimulation has clarified the principles governing the functioning of the retriggerable RP. When the RP is retriggered three times in the course of a single pacemaker cycle, the pacer varies its mode of functioning, being the pacing rate increased to a value identical to the magnet rate. Furthermore, the RP is extremely prolonged, occupying the 90% of the pacing interval; only impulses occurring during the last 80 ms, thus, are able to reset the PM.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged

[Reduction of the threshold of myocardial excitability after an extremely long asystolic pause: late phase of "supernormal excitability?].

A patient with a malfunctioning pacemaker due to lead insulation defect is reported. High voltage stimuli were always effective, while when the pulse amplitude was reduced to 3.8 volt stimuli were uneffective except when occurring after extremely long asystolic pauses. An advanced exit block (up to 7:1) thus occurred. Late lowering of the myocardial threshold of excitability could be explained by slow spontaneous diastolic depolarization occurring in myocardial fibers surrounding the tip of the electrode.

Aged

Antibacterial drugs in Crohn's disease.

The evidence of a beneficial role of antibacterial drugs in Crohn's disease is largely empirical. Data accumulate to show that these drugs may well be used as an adjunctive therapy to oral anti-inflammatory drugs. Circumstantial evidence has also been provided that antibacterial drugs are effective in relieving symptoms related to bacterial overgrowth and when used for specific indications such as perianal lesions.

Anti-Bacterial Agents